Hegemonic structure of basic, clinical and patented knowledge on Ebola research: a US army reductionist initiative [PDF]
Background: In this paper, we present an approach to understand how the basic, clinical and patent knowledge on Ebola is organized and intercommunicated and what leading factor could be shaping the evolution of the knowledge translation process for this disease.
arxiv +1 more source
The basement membrane protein nidogen-1 supports platelet adhesion and activation
The core structure of the extracellular basement membrane is made up of self-assembling networks of collagen and laminin which associate with each other through the bridging adapter proteins including the sulfated monomeric glycoprotein nidogen.
Hari Hara Sudhan Lakshmanan+12 more
doaj +1 more source
Thirty-Two Years of IEEE VIS: Authors, Fields of Study and Citations [PDF]
The IEEE VIS Conference (VIS) recently rebranded itself as a unified conference and officially positioned itself within the discipline of Data Science. Driven by this movement, we investigated (1) who contributed to VIS, and (2) where VIS stands in the scientific world.
arxiv
Structural basis for the shielding function of the dynamic trypanosome variant surface glycoprotein coat [PDF]
The most prominent defence of the unicellular parasite Trypanosoma brucei against the host immune system is a dense coat that comprises a variant surface glycoprotein (VSG). Despite the importance of the VSG family, no complete structure of a VSG has been reported.
arxiv +1 more source
Spatiotemporal Expression of Pregnancy-Specific Glycoprotein Gene rnCGMl in Rat Placenta [PDF]
As a basis towards a better understanding of the role of the pregnancy-specific glycoprotein (PSG) family in the maintenance of pregnancy, detailed investigations are described on the expression of a recently identified rat PSG gene (rnCGM1) at the mRNA ...
Lucas, Kurt+4 more
core +1 more source
Despite significant advances in the treatment of thrombogenic diseases, antiplatelet therapies are still associated with a high bleeding risk. Consequently, potential benefits of preventing thromboembolic events by pharmacological agents need to be ...
Augusto Martins Lima+4 more
semanticscholar +1 more source
Assembly of the Inner Perivitelline Layer, a Homo log of the Mammalian Zona Pellucida: An Immunohistochemical and Ultrastructural Study [PDF]
The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional
Bausek N.+37 more
core +1 more source
A comparative analysis for SARS-CoV-2 [PDF]
COVID-19 has affected the world tremendously. It is critical that biological experiments and clinical designs are informed by computational approaches for time- and cost-effective solutions. Comparative analyses particularly can play a key role to reveal structural changes in proteins due to mutations, which can lead to behavioural changes, such as the
arxiv
Topographical mapping of epitopes on the glycoproteins of murine hepatitis virus-4 (strain JHM): correlation with biological activities. [PDF]
Monoclonal hybridoma antibodies (MAb) of defined polypeptide specificity and biological activity were used in a competition binding assay to identify antibody binding sites (epitopes) on the glycoproteins of murine hepatitis virus-4 strain JHM (MHV-4 ...
Buchmeier, MJ+3 more
core
Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S+8 more
core +3 more sources