Results 111 to 120 of about 4,441 (208)

Glycomics and glycoproteomics.

SEIBUTSU BUTSURI KAGAKU, 2006
In glycoproteomics, key structural issues, protein identification, locations of glycosylation sites, and the glycosylation site microheterogeneity, should be evaluated in a large number of glycoproteins. To this end, a simple and efficient method, utilizing hydrophilic binding of carbohydrate matrixes such as cellulose and Sepharose to oligosaccharides,
openaire   +2 more sources

A Computational and Chemical Design Strategy for Manipulating Glycan‐Protein Recognition

Advanced Science
Glycans are complex biomolecules that encode rich information and regulate various biological processes, such as fertilization, host‐pathogen binding, and immune recognition, through interactions with glycan‐binding proteins.
Qiang Zhu, Didi Geng, Jingchao Li, Jinqiu Zhang, Haofan Sun, Zhiya Fan, Jiahui He, Ninghui Hao, Yinping Tian, Liuqing Wen, Tiehai Li, Weijie Qin, Xiakun Chu, Yong Wang, Wen Yi   +14 more
doaj   +1 more source

Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics [PDF]

, 2014
Purpose: Extracellular proteins are easily accessible, which presents a subproteome of molecular targets that have high diagnostic and therapeutic potential.
Zhang, Hui, Koganti, Tejaswi, Modesti, Alessandra, Yuan Tian, Kristine DeLeon‐Pennell, Yonggang Ma, Laura Pietrovito, Deleon-Pennell, Kristine, Aiyetan, Paul, Ma, Yonggang, Hui Zhang, Hicks, Chindo, Chindo Hicks, Ganesh V. Halade, Cannon, Presley, Presley Cannon, Merry L. Lindsey, Yao, Zhihao, Shah, Punit, Punit Shah, Paul Aiyetan, Halade, Ganesh V., Tian, Yuan, Lindsey, Merry L., Alessandra Modesti, Zhihao Yao, Pietrovito, Laura, Tejaswi Koganti   +27 more
core   +1 more source

Mapping the O‐glycoproteome using site‐specific extraction of O‐linked glycopeptides (EXoO)

Molecular Systems Biology, 2018
Protein glycosylation is one of the most abundant post‐translational modifications. However, detailed analysis of O‐linked glycosylation, a major type of protein glycosylation, has been severely impeded by the scarcity of suitable methodologies.
Weiming Yang, Minghui Ao, Yingwei Hu, Qing Kay Li, Hui Zhang   +4 more
doaj   +1 more source

IgG subclass-specific N-glycosylation differentiates HRCT subtypes in idiopathic inflammatory myopathies-associated ILD

Frontiers in Immunology
IntroductionIdiopathic inflammatory myopathies (IIMs) frequently involve interstitial lung disease (ILD), a major contributor to morbidity and mortality. However, the immunological heterogeneity across radiologic ILD subtypes remains poorly defined. This
Tong Wu, Tong Wu, Yanhong Li, Yanhong Li, Yingying Ling, Yubin Luo, Yinlan Wu, Yinlan Wu, Jing Zhao, Lu Cheng, Chunyu Tan, Yong Zhang, Yong Zhang, Yi Liu, Yi Liu, Yi Liu   +15 more
doaj   +1 more source

Structural and functional glycosphingolipidomics by glycoblotting with aminooxy-functionalized gold nanoparticle [PDF]

, 2008
Glycosphingolipids (GSLs) synthesized in Golgi apparatus by sequential transfer of sugar residues to a ceramide lipid anchor are ubiquitously distributing on vertebrate plasma membranes.
Midori Abe, Noriko Nagahori, Shin-Ichiro Nishimura   +2 more
core  

Sustainable Phosphorylated Cellulose Nanocrystals: A Dual‐Affinity Platform for High‐Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides

Advanced Science
Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li, Wuming Fan, Xuyang Yue, Dongdong Wang, Xiangyu Tang, Zhuo Zhang, Yonggui Wang, Yanjun Xie, Mingliang Ye, Hongqiang Qin   +9 more
doaj   +1 more source

Identification of potential biomarkers of oral squamous cell carcinoma using integrated proteomics and glycoproteomics and glycoproteomics analyses

, 2020
Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades.
Wong, Yin Ling
core  

Identification of potential biomarkers of oral squamous cell carcinoma using integrated proteomics and glycoproteomics and glycoproteomics analyses / Wong Yin Ling

, 2020
Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades.
Wong, Yin Ling
core  

Advances in LC-MS/MS-based glycoproteomics: Getting closer to system-wide site-specific mapping of the N- and O-glycoproteome

, 2014
Site-specific structural characterization of glycoproteins is important for understanding the exact functional relevance of protein glycosylation. Resulting partly from the multiple layers of structural complexity of the attached glycans, the system-wide
Packer, Nicolle H., Thaysen-Andersen, Morten   +1 more
core   +1 more source