Results 111 to 120 of about 6,118 (218)

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]

, 2018
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn, Hsieh, Hsiao-Wu, Park, Simon S   +2 more
core   +1 more source

A Computational and Chemical Design Strategy for Manipulating Glycan‐Protein Recognition

Advanced Science
Glycans are complex biomolecules that encode rich information and regulate various biological processes, such as fertilization, host‐pathogen binding, and immune recognition, through interactions with glycan‐binding proteins.
Qiang Zhu, Didi Geng, Jingchao Li, Jinqiu Zhang, Haofan Sun, Zhiya Fan, Jiahui He, Ninghui Hao, Yinping Tian, Liuqing Wen, Tiehai Li, Weijie Qin, Xiakun Chu, Yong Wang, Wen Yi   +14 more
doaj   +1 more source

Metabolic reprogramming of murine cardiomyocytes during autophagy requires the extracellular nutrient sensor decorin. [PDF]

, 2018
The extracellular matrix is a master regulator of tissue homeostasis in health and disease. Here we examined how the small, leucine-rich, extracellular matrix proteoglycan decorin regulates cardiomyocyte metabolism during fasting in vivo.
Gubbiotti, Maria A., Hoek, Jan B., Iozzo, Renato V., Rodeck, Ulrich, Seifert, Erin L.   +4 more
core   +1 more source

IgG subclass-specific N-glycosylation differentiates HRCT subtypes in idiopathic inflammatory myopathies-associated ILD

Frontiers in Immunology
IntroductionIdiopathic inflammatory myopathies (IIMs) frequently involve interstitial lung disease (ILD), a major contributor to morbidity and mortality. However, the immunological heterogeneity across radiologic ILD subtypes remains poorly defined. This
Tong Wu, Tong Wu, Yanhong Li, Yanhong Li, Yingying Ling, Yubin Luo, Yinlan Wu, Yinlan Wu, Jing Zhao, Lu Cheng, Chunyu Tan, Yong Zhang, Yong Zhang, Yi Liu, Yi Liu, Yi Liu   +15 more
doaj   +1 more source

UniCarbKB: building a knowledge platform for glycoproteomics [PDF]

, 2017
The UniCarb KnowledgeBase (UniCarbKB; http://unicarbkb.org) offers public access to a growing, curated database of information on the glycan structures of glycoproteins.
Akune, Yukie, Aoki-Kinoshita, Kiyoko F., Campbell, Matthew P., Gasteiger, Elisabeth, Lisacek, Frederique, Mariethoz, Julien, Packer, Nicolle H., Peterson, Robyn   +7 more
core  

glycoproteomics

Citation: 'glycoproteomics' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09822 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology
Circulating tumor cells (CTCs) are cancer cells that detach from the original site and reach the bloodstream. The most aggressive CTCs survive various immune system attacks and initiate metastasis formation.
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
doaj   +1 more source

Glycomics and glycoproteomics.

SEIBUTSU BUTSURI KAGAKU, 2006
In glycoproteomics, key structural issues, protein identification, locations of glycosylation sites, and the glycosylation site microheterogeneity, should be evaluated in a large number of glycoproteins. To this end, a simple and efficient method, utilizing hydrophilic binding of carbohydrate matrixes such as cellulose and Sepharose to oligosaccharides,
openaire   +2 more sources

Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification

Frontiers in Molecular Biosciences
Sulfated N-glycans from human immunoglobulin A (IgA) were recently discovered via glycomic approaches. However, their site-specific description is still pending.
Frania J. Zuniga-Banuelos, Frania J. Zuniga-Banuelos, Greta Lemke, Greta Lemke, Marcus Hoffmann, Udo Reichl, Udo Reichl, Erdmann Rapp, Erdmann Rapp   +8 more
doaj   +1 more source

Glycoproteomics: New Technology Developments and Applications Provide Renewed Interest in Glycoproteins [PDF]

, 2008

core   +1 more source