Results 111 to 120 of about 4,132 (206)

Identification of potential biomarkers of oral squamous cell carcinoma using integrated proteomics and glycoproteomics and glycoproteomics analyses / Wong Yin Ling

open access: yes, 2020
Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades.
Wong, Yin Ling
core  

Databases and Bioinformatic Tools for Glycobiology and Glycoproteomics

open access: yes, 2020
Glycosylation plays critical roles in various biological processes and is closely related to diseases. Deciphering the glycocode in diverse cells and tissues offers opportunities to develop new disease biomarkers and more effective recombinant ...
Xiaokun Hong   +4 more
core   +1 more source

Multi Omics Applications in Biological Systems

open access: yesCurrent Issues in Molecular Biology
Traditional methodologies often fall short in addressing the complexity of biological systems. In this regard, system biology omics have brought invaluable tools for conducting comprehensive analysis.
Cristian D. Gutierrez Reyes   +9 more
doaj   +1 more source

Glycoproteomics analysis of complement factor H and its complement-regulatory function during Streptococcus pneumoniae-associated hemolytic uremic syndrome

open access: yesFrontiers in Immunology
Hemolytic uremic syndrome caused by an invasive Streptococcus pneumoniae infection (SP-HUS) is a rare and severe disease that primarily affects children under two years of age.
Laura M. Baas   +16 more
doaj   +1 more source

Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics

open access: yes, 2014
Purpose: Extracellular proteins are easily accessible, which presents a subproteome of molecular targets that have high diagnostic and therapeutic potential.
Zhang, Hui   +27 more
core   +1 more source

Population-level analysis of glycoprotein glycoforms

open access: yesmAbs
The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations – variants sharing a protein backbone but ...
Alejandro Gomez Toledo   +8 more
doaj   +1 more source

Application Progress of Chemoenzymatic Labeling-Assisted Mass Spectrometry in Protein Glycosylation Analysis

open access: yesZhipu Xuebao
Protein glycosylation is one of the most abundant and structurally diverse post-translational modifications (PTMs) in eukaryotic systems. Unlike template-driven biosynthesis, glycosylation is synergistically regulated by multiple glycosyltransferases ...
Chen-yang ZHAO, Zhong-hua LI, Hao-jie LU
doaj   +1 more source

IgG subclass-specific N-glycosylation differentiates HRCT subtypes in idiopathic inflammatory myopathies-associated ILD

open access: yesFrontiers in Immunology
IntroductionIdiopathic inflammatory myopathies (IIMs) frequently involve interstitial lung disease (ILD), a major contributor to morbidity and mortality. However, the immunological heterogeneity across radiologic ILD subtypes remains poorly defined. This
Tong Wu   +15 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology
Circulating tumor cells (CTCs) are cancer cells that detach from the original site and reach the bloodstream. The most aggressive CTCs survive various immune system attacks and initiate metastasis formation.
Doryan Masmoudi   +3 more
doaj   +1 more source

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