Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, Volume 16, Issue 2, Page 243-251, February 2026.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion [PDF]
, 2019 Aberrant display of the truncated core1 O-glycan T-antigen is a common feature of human cancer cells that correlates with metastasis. Here we show that T-antigen in Drosophila melanogaster macrophages is involved in their developmentally programmed ...
Aebi +154 more
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Frontiers in Endocrinology, 2018 O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation occurs in a wide range of diseases, including cancer, diabetes, and ...
Nathan J. Cox +5 more
doaj +1 more source
GOLPH2 expression may serve as diagnostic marker in seminomas [PDF]
, 2010 : BACKGROUND: GOLPH2 (Golgi phosphoprotein 2) is a novel Golgi membrane protein. Despite its unknown physiologic function, however, it has been proposed as a biomarker for hepatocellular and prostate carcinoma due to its upregulation in those cancer ...
Florian R Fritzsche +25 more
core +1 more source
Towards an automated analysis of bacterial peptidoglycan structure. [PDF]
, 2016 Peptidoglycan (PG) is an essential component of the bacterial cell envelope. This macromolecule consists of glycan chains alternating N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides containing nonstandard amino acids ...
A Atrih +18 more
core +2 more sources
Mapping the O‐glycoproteome using site‐specific extraction of O‐linked glycopeptides (EXoO)
Molecular Systems Biology, 2018 Protein glycosylation is one of the most abundant post‐translational modifications. However, detailed analysis of O‐linked glycosylation, a major type of protein glycosylation, has been severely impeded by the scarcity of suitable methodologies.
Weiming Yang +4 more
doaj +1 more source
Site-Specific Glycoprofiles of HDL-Associated ApoE are Correlated with HDL Functional Capacity and Unaffected by Short-Term Diet. [PDF]
, 2019 Since high-density lipoprotein (HDL) glycoprofiles are associated with HDL functional capacity, we set out to determine whether diet can alter the glycoprofiles of key HDL-associated proteins, including ApoE, a potent driver of chronic disease risk.
Beals, Elizabeth +8 more
core
A novel mass spectrometric strategy "bEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli [PDF]
, 2016 © The Author(s) 2016. The attachment of sugars to proteins via side-chain oxygen atoms (O-linked glycosylation) is seen in all three domains of life.
Boysen, A +5 more
core +2 more sources
Glycans and glycosaminoglycans in neurobiology: key regulators of neuronal cell function and fate [PDF]
, 2018 The aim of the present study was to examine the roles of l-fucose and the glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate (CS/DS) with selected functional molecules in neural tissues.
Hayes, Anthony J., Melrose, James
core +2 more sources
The SIB Swiss Institute of Bioinformatics’ resources : focus on curated databases [PDF]
, 2015 The SIB Swiss Institute of Bioinformatics provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry.
Anisimova, Maria +3 more
core +1 more source