Results 81 to 90 of about 3,095 (176)

Glycomics and glycoproteomics.

SEIBUTSU BUTSURI KAGAKU, 2006
In glycoproteomics, key structural issues, protein identification, locations of glycosylation sites, and the glycosylation site microheterogeneity, should be evaluated in a large number of glycoproteins. To this end, a simple and efficient method, utilizing hydrophilic binding of carbohydrate matrixes such as cellulose and Sepharose to oligosaccharides,
openaire   +2 more sources

Glycoproteins and glycoproteomics in pancreatic cancer

World Journal of Gastroenterology, 2016
Aberrations in protein glycosylation and polysaccharides play a pivotal role in pancreatic tumorigenesis, influencing cancer progression, metastasis, immuno-response and chemoresistance. Abnormal expression in sugar moieties can impact the function of various glycoproteins, including mucins, surface receptors, adhesive proteins, proteoglycans, as well ...
Pan, Sheng, Brentnall, Teresa A, Chen, Ru   +2 more
openaire   +2 more sources

Mapping the O‐glycoproteome using site‐specific extraction of O‐linked glycopeptides (EXoO)

Molecular Systems Biology, 2018
Protein glycosylation is one of the most abundant post‐translational modifications. However, detailed analysis of O‐linked glycosylation, a major type of protein glycosylation, has been severely impeded by the scarcity of suitable methodologies.
Weiming Yang, Minghui Ao, Yingwei Hu, Qing Kay Li, Hui Zhang   +4 more
doaj   +1 more source

IgG subclass-specific N-glycosylation differentiates HRCT subtypes in idiopathic inflammatory myopathies-associated ILD

Frontiers in Immunology
IntroductionIdiopathic inflammatory myopathies (IIMs) frequently involve interstitial lung disease (ILD), a major contributor to morbidity and mortality. However, the immunological heterogeneity across radiologic ILD subtypes remains poorly defined. This
Tong Wu, Tong Wu, Yanhong Li, Yanhong Li, Yingying Ling, Yubin Luo, Yinlan Wu, Yinlan Wu, Jing Zhao, Lu Cheng, Chunyu Tan, Yong Zhang, Yong Zhang, Yi Liu, Yi Liu, Yi Liu   +15 more
doaj   +1 more source

Sustainable Phosphorylated Cellulose Nanocrystals: A Dual‐Affinity Platform for High‐Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides

Advanced Science
Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li, Wuming Fan, Xuyang Yue, Dongdong Wang, Xiangyu Tang, Zhuo Zhang, Yonggui Wang, Yanjun Xie, Mingliang Ye, Hongqiang Qin   +9 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology
Circulating tumor cells (CTCs) are cancer cells that detach from the original site and reach the bloodstream. The most aggressive CTCs survive various immune system attacks and initiate metastasis formation.
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
doaj   +1 more source

Immunoglobulin A carries sulfated and O-acetylated N-glycans primarily at the tailpiece site – strategies for site-specific N-glycan identification

Frontiers in Molecular Biosciences
Sulfated N-glycans from human immunoglobulin A (IgA) were recently discovered via glycomic approaches. However, their site-specific description is still pending.
Frania J. Zuniga-Banuelos, Frania J. Zuniga-Banuelos, Greta Lemke, Greta Lemke, Marcus Hoffmann, Udo Reichl, Udo Reichl, Erdmann Rapp, Erdmann Rapp   +8 more
doaj   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Proteomic Analysis of Extracellular Vesicles Identifies CDCP1 as Critical Metastasis‐Related Glycoprotein in Lung Cancer

Journal of Extracellular Vesicles
Lung cancer is the most prevalent malignancy worldwide, with the majority of fatalities attributed to metastasis. Recent studies have demonstrated the pivotal role of extracellular vesicles (EVs) and glycoproteins in tumor progression.
Lu Zhang, Yan Wu, Suntao Li, Miao Guo, Jiaqi Zhao, Chengxi Cao, Yan Zhang, Hua Xiao   +7 more
doaj   +1 more source

Glycoproteomics: protein modifications for versatile functions [PDF]

The EMBO Reports, 2005
Reiko T, Lee, Gordan, Lauc, Yuan C, Lee
openaire   +2 more sources