Results 71 to 80 of about 4,132 (206)
Fragmentation characteristics of glycopeptides [PDF]
, 2013 Mass spectrometric analysis of glycopeptides is an emerging strategy for analysis of glycosylation patterns. Here we present an approach using energy resolved collision induced decomposition (CID) spectra to determine structural features of glycopeptides.
Jekő, Anita +6 more
core +1 more source
MoleculesRegular monitoring of patients with a history of hepatitis C virus (HCV) infection is critical for the detection and management of hepatocellular carcinoma (HCC).
Hiroko Shimazaki +7 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Chymase, a mast cell serine protease involved in the generation of multiple cardiovascular factors, such as angiotensin II and endothelin-1 (ET-1), is elevated and participates in tissue degeneration after permanent myocardial infarction (PMI ...
Martin Houde +15 more
doaj +1 more source
Proteomics and glycoproteomics of beer and wine
PROTEOMICS, 2022 AbstractBeer and wine are fermented beverages that contain abundant proteins released from barley or grapes, and secreted from yeast. These proteins are associated with many quality attributes including turbidity, foamability, effervescence, flavour and colour. Many grape proteins and secreted yeast proteins are glycosylated, and barley proteins can be
Shulei Liu +3 more
openaire +4 more sources
Prediction of glycopeptide fragment mass spectra by deep learning
Nature CommunicationsDeep learning has achieved a notable success in mass spectrometry-based proteomics and is now emerging in glycoproteomics. While various deep learning models can predict fragment mass spectra of peptides with good accuracy, they cannot cope with the non ...
Yi Yang, Qun Fang
doaj +1 more source
Progress of metabolomics‐centric multi‐omics research in medicine
iMetaOmics, Volume 3, Issue 2, June 2026.The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang +6 more
wiley +1 more source
Frontiers in Chemistry, 2022 Site-specific N-glycosylation characterization requires intact N-glycopeptide analysis based on suitable tandem mass spectrometry (MS/MS) method. Electron-transfer/higher-energy collisional dissociation (EThcD), stepped collision energy/higher-energy ...
Wenjuan Zeng +13 more
doaj +1 more source
Progress in Natural Products Target Discovery Technology
MedComm, Volume 7, Issue 6, June 2026.Here, we provide a comprehensive overview of current technologies and recent advancements in therapeutic target discovery for natural products. By systematically synthesizing the principles, methodologies, and practical applications of existing experimental and computational strategies, this work provides a more actionable reference framework for ...
Qiyuan Pan +7 more
wiley +1 more source
Hepatology Research, Volume 56, Issue 6, Page 944-955, June 2026.In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki +7 more
wiley +1 more source
Bifunctional Monosaccharides Preferentially Localize to Nuclear Subcompartments
ChemBioChem, Volume 27, Issue 10, 27 May 2026.Bifunctional N‐acetylgalactosamine and N‐acetylglucosamine analogues were generated and used for visualizing the subcellular localization of monosaccharides. Using these probes, we provide direct evidence for partitioning of monosaccharides into highly metabolically active nuclear subcompartments.
Pavel Barahtjan +4 more
wiley +1 more source