Results 71 to 80 of about 4,441 (208)
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Glycoproteomics: A Balance between High-Throughput and In-Depth Analysis [PDF]
, 2017 Glycoproteomics is an important subdiscipline of proteomics. Mass spectrometry (MS)-based glycoproteomics has relied so far on two levels of analysis, targeting either the released glycans or digested glycopeptides.
Heck, Albert J R +4 more
core +2 more sources
Proteomics and glycoproteomics of beer and wine
PROTEOMICS, 2022 AbstractBeer and wine are fermented beverages that contain abundant proteins released from barley or grapes, and secreted from yeast. These proteins are associated with many quality attributes including turbidity, foamability, effervescence, flavour and colour. Many grape proteins and secreted yeast proteins are glycosylated, and barley proteins can be
Shulei Liu +3 more
openaire +4 more sources
European Journal of Pain, Volume 30, Issue 8, September 2026.ABSTRACT Background Altered immunoglobulin G (IgG) glycosylation was implicated in various conditions, but its role in fibromyalgia (FM) remains unclear. This study investigated IgG glycosylation patterns in FM patients and associations between glycosylation changes and clinical profiles.
Ling‐Cheng Kung +4 more
wiley +1 more source
Frontiers in Pharmacology, 2018 Chymase, a mast cell serine protease involved in the generation of multiple cardiovascular factors, such as angiotensin II and endothelin-1 (ET-1), is elevated and participates in tissue degeneration after permanent myocardial infarction (PMI ...
Martin Houde +15 more
doaj +1 more source
Bioengineering, 2020 Comprehensive analysis of the glycoproteome is critical due to the importance of glycosylation to many aspects of protein function. The tremendous complexity of this post-translational modification, however, makes it difficult to adequately characterize ...
Joseph L. Mertz +7 more
doaj +1 more source
Expanding the Chondroitin Sulfate Glycoproteome — But How Far?
Frontiers in Cell and Developmental Biology, 2021 Chondroitin sulfate proteoglycans (CSPGs) are found at cell surfaces and in connective tissues, where they interact with a multitude of proteins involved in various pathophysiological processes.
Fredrik Noborn +5 more
doaj +1 more source
Comparative glycoproteomics: approaches and applications [PDF]
Briefings in Functional Genomics and Proteomics, 2008 Glycosylation plays fundamental roles in controlling various biological processes. Therefore, glycosylation analysis has become an important target for proteomic research and has great potential for clinical applications. With the continuous development and refinement of glycoprotein isolation methods, increasing attention has been directed to the ...
Xin, Wei, Lingjun, Li
openaire +2 more sources
Prediction of glycopeptide fragment mass spectra by deep learning
Nature CommunicationsDeep learning has achieved a notable success in mass spectrometry-based proteomics and is now emerging in glycoproteomics. While various deep learning models can predict fragment mass spectra of peptides with good accuracy, they cannot cope with the non ...
Yi Yang, Qun Fang
doaj +1 more source
Frontiers in Chemistry, 2021 Diabetes has become a major public health concern worldwide, most of which are type 2 diabetes (T2D). The diagnosis of T2D is commonly based on plasma glucose levels, and there are no reliable clinical biomarkers available for early detection.
Yang Zhao +12 more
doaj +1 more source