Results 61 to 70 of about 3,095 (176)
MoleculesRegular monitoring of patients with a history of hepatitis C virus (HCV) infection is critical for the detection and management of hepatocellular carcinoma (HCC).
Hiroko Shimazaki +7 more
doaj +1 more source
Frontiers in Chemistry, 2021 Diabetes has become a major public health concern worldwide, most of which are type 2 diabetes (T2D). The diagnosis of T2D is commonly based on plasma glucose levels, and there are no reliable clinical biomarkers available for early detection.
Yang Zhao +12 more
doaj +1 more source
O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
Advanced Science, Volume 13, Issue 37, 3 July 2026.This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
Proteomics and glycoproteomics of beer and wine
PROTEOMICS, 2022 AbstractBeer and wine are fermented beverages that contain abundant proteins released from barley or grapes, and secreted from yeast. These proteins are associated with many quality attributes including turbidity, foamability, effervescence, flavour and colour. Many grape proteins and secreted yeast proteins are glycosylated, and barley proteins can be
Shulei Liu +3 more
openaire +4 more sources
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Mass Spectrometry Reviews, Volume 45, Issue 4, Page 599-623, July/August 2026.Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
MedComm, Volume 7, Issue 7, July 2026.Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
Molecular Oncology, 2022 Primary liver cancer, mainly comprising hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), remains a major global health problem. Although ICC is clinically different from HCC, their molecular differences are still largely unclear.
Jun Li +11 more
doaj +1 more source
Proteoglycan Research, Volume 4, Issue 3, July 2026.ABSTRACT The Ehlers–Danlos syndromes (EDS) are a group of heritable connective tissue disorders, characterized by varying degrees of joint hypermobility, skin hyperextensibility and extracellular matrix defects. Spondylodysplastic type of EDS (spEDS) is a rare type of this group that can be caused by pathogenic variants in the B3GALT6 gene, coding for ...
Noborn Fredrik +6 more
wiley +1 more source
Advanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni +13 more
wiley +1 more source
Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems
Advanced Science, Volume 13, Issue 31, 4 June 2026.A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller +9 more
wiley +1 more source