Results 41 to 50 of about 4,132 (206)
Differential Glycosite Profiling—A Versatile Method to Compare Membrane Glycoproteomes
Molecules, 2021 Glycosylation is the most prevalent and varied form of post-translational protein modifications. Protein glycosylation regulates multiple cellular functions, including protein folding, cell adhesion, molecular trafficking and clearance, receptor ...
Malwina Michalak +8 more
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JIMD Reports, 2022 The spondylodysplastic type of Ehlers–Danlos syndrome (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate ...
Mahnaz Nikpour +7 more
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Frontiers in Immunology, 2023 The clinical success of immune-checkpoint inhibitors (ICI) in both resected and metastatic melanoma has confirmed the validity of therapeutic strategies that boost the immune system to counteract cancer.
Chad Pickering +20 more
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Glycoproteomics and clinical applications [PDF]
PROTEOMICS – Clinical Applications, 2010 AbstractGlycosylation is the most structurally complicated and diverse type of protein modifications. Protein glycosylation has long been recognized to play fundamental roles in many biological processes, as well as in disease genesis and progression. Glycoproteomics focuses on characterization of proteins modified by carbohydrates.
Yuan, Tian, Hui, Zhang
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N-glycoproteomics of brain synapses and synaptic vesicles
, 2023 R scripts for N-glycoproteomics ...
Bradberry, Mazdak
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Serum Glycoproteomic Alterations in Patients with Diabetic Retinopathy
Proteomes, 2020 The precise molecular mechanisms of diabetic retinopathy (DR) pathogenesis are unclear, and treatment options are limited. There is an urgent need to discover and develop novel therapeutic targets for the treatment of this disease.
Ashok Sharma +8 more
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Recent advances in glycoinformatic platforms for glycomics and glycoproteomics
, 2020 Protein glycosylation is the most complex and prevalent post-translation modification in terms of the number of proteins modified and the diversity generated. To understand the functional roles of glycoproteins it is important to gain an insight into the
Abrahams, Jodie L. +6 more
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A Perspective on Extracellular Vesicles Proteomics
Frontiers in Chemistry, 2017 Increasing attention has been given to secreted extracellular vesicles (EVs) in the past decades, especially in the portrayal of their molecular cargo and role as messengers in both homeostasis and pathophysiological conditions.
Livia Rosa-Fernandes +6 more
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Frontiers in Immunology, 2021 Deciphering the glycosylation of the viral envelope (Env) glycoprotein is critical for evaluating viral escape from the host’s immune response and developing vaccines and antiviral drugs.
Yong Zhang +14 more
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A high-resolution N-glycoproteome landscape of aging mouse ovary
Redox BiologyOvarian aging typically precedes the decline of other organ systems, yet its molecular mechanisms remain poorly understood. Glycosylation as one of the most important protein modifications has been especially unexplored in this context.
Yongqi Wu +11 more
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