Results 41 to 50 of about 4,441 (208)

Glycoproteomics in neurodegenerative diseases [PDF]

Mass Spectrometry Reviews, 2009
AbstractProtein glycosylation regulates protein function and cellular distribution. Additionally, aberrant protein glycosylations have been recognized to play major roles in human disorders, including neurodegenerative diseases. Glycoproteomics, a branch of proteomics that catalogs and quantifies glycoproteins, provides a powerful means to ...
Hwang, Hyejin, Zhang, Jianpeng, Chung, Kathryn A., Leverenz, James B., Zabetian, Cyrus P., Peskind, Elaine R., Jankovic, Joseph, Su, Zhen, Hancock, Aneeka M., Pan, Catherine, Montine, Thomas J., Pan, Sheng, Nutt, John, Albin, Roger L., Gearing, Marla, Beyer, Richard P., Shi, Min, Zhang, Jing   +17 more
openaire   +3 more sources

N-glycoproteins in Plant Cell Walls: A Survey

Plants, 2022
Cell walls are an extracellular compartment specific to plant cells, which are not found in animal cells. Their composition varies between cell types, plant species, and physiological states.
Hélène San Clemente, Elisabeth Jamet
doaj   +1 more source

Differential Glycosite Profiling—A Versatile Method to Compare Membrane Glycoproteomes

Molecules, 2021
Glycosylation is the most prevalent and varied form of post-translational protein modifications. Protein glycosylation regulates multiple cellular functions, including protein folding, cell adhesion, molecular trafficking and clearance, receptor ...
Malwina Michalak, Martin Simon Kalteis, Aysel Ahadova, Matthias Kloor, Mark Kriegsmann, Katharina Kriegsmann, Uwe Warnken, Dominic Helm, Jürgen Kopitz   +8 more
doaj   +1 more source

Glycoproteomics and clinical applications [PDF]

PROTEOMICS – Clinical Applications, 2010
AbstractGlycosylation is the most structurally complicated and diverse type of protein modifications. Protein glycosylation has long been recognized to play fundamental roles in many biological processes, as well as in disease genesis and progression. Glycoproteomics focuses on characterization of proteins modified by carbohydrates.
Yuan, Tian, Hui, Zhang
openaire   +2 more sources

Glycosaminoglycan linkage region of urinary bikunin as a potentially useful biomarker for β3GalT6‐deficient spondylodysplastic Ehlers–Danlos syndrome

JIMD Reports, 2022
The spondylodysplastic type of Ehlers–Danlos syndrome (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate ...
Mahnaz Nikpour, Fredrik Noborn, Jonas Nilsson, Tim Van Damme, Olivier Kaye, Delfien Syx, Fransiska Malfait, Göran Larson   +7 more
doaj   +1 more source

Plasma glycoproteomic biomarkers identify metastatic melanoma patients with reduced clinical benefit from immune checkpoint inhibitor therapy

Frontiers in Immunology, 2023
The clinical success of immune-checkpoint inhibitors (ICI) in both resected and metastatic melanoma has confirmed the validity of therapeutic strategies that boost the immune system to counteract cancer.
Chad Pickering, Paul Aiyetan, Gege Xu, Alan Mitchell, Rachel Rice, Yana G. Najjar, Joseph Markowitz, Joseph Markowitz, Lisa M. Ebert, Lisa M. Ebert, Lisa M. Ebert, Michael P. Brown, Michael P. Brown, Michael P. Brown, Gonzalo Tapia-Rico, Dennie Frederick, Xin Cong, Daniel Serie, Klaus Lindpaintner, Flavio Schwarz, Genevieve M. Boland   +20 more
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Serum Glycoproteomic Alterations in Patients with Diabetic Retinopathy

Proteomes, 2020
The precise molecular mechanisms of diabetic retinopathy (DR) pathogenesis are unclear, and treatment options are limited. There is an urgent need to discover and develop novel therapeutic targets for the treatment of this disease.
Ashok Sharma, James Cox, Joshua Glass, Tae Jin Lee, Sai Karthik Kodeboyina, Wenbo Zhi, Lane Ulrich, Zachary Lukowski, Shruti Sharma   +8 more
doaj   +1 more source

N-glycoproteomics of brain synapses and synaptic vesicles

, 2023
R scripts for N-glycoproteomics ...
Bradberry, Mazdak
core   +1 more source

Recent advances in glycoinformatic platforms for glycomics and glycoproteomics

, 2020
Protein glycosylation is the most complex and prevalent post-translation modification in terms of the number of proteins modified and the diversity generated. To understand the functional roles of glycoproteins it is important to gain an insight into the
Abrahams, Jodie L., Campbell, Matthew P, Járvás, Gábor, Zhou, Yaoqi, Taherzadeh, Ghazaleh, Abrahams, Jodie L, Guttman, András   +6 more
core   +1 more source

A Perspective on Extracellular Vesicles Proteomics

Frontiers in Chemistry, 2017
Increasing attention has been given to secreted extracellular vesicles (EVs) in the past decades, especially in the portrayal of their molecular cargo and role as messengers in both homeostasis and pathophysiological conditions.
Livia Rosa-Fernandes, Victória Bombarda Rocha, Victor Corasolla Carregari, Andrea Urbani, Andrea Urbani, Giuseppe Palmisano, Giuseppe Palmisano   +6 more
doaj   +1 more source