Results 21 to 30 of about 3,095 (176)
Glycoproteomic and glycomic databases [PDF]
Clinical Proteomics, 2014 Protein glycosylation serves critical roles in the cellular and biological processes of many organisms. Aberrant glycosylation has been associated with many illnesses such as hereditary and chronic diseases like cancer, cardiovascular diseases, neurological disorders, and immunological disorders. Emerging mass spectrometry (MS) technologies that enable
Baycin Hizal, Deniz +7 more
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GlypNirO: An automated workflow for quantitative N- and O-linked glycoproteomic data analysis
Beilstein Journal of Organic Chemistry, 2020 Mass spectrometry glycoproteomics is rapidly maturing, allowing unprecedented insights into the diversity and functions of protein glycosylation. However, quantitative glycoproteomics remains challenging.
Toan K. Phung +2 more
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Ion Mobility-Mass Spectrometry and its Applications in Protein Glycosylation Research [PDF]
Zhipu Xuebao, 2022 Glycosylation is one of the most important post-translational modifications (PTM), mediating physiological processes like cell adhesion, cell proliferation, cell signaling, and immune responses.
FU Bin1, LIANG Yu-ying1, LU Hao-jie1,2
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Microarrays in Glycoproteomics Research [PDF]
Clinics in Laboratory Medicine, 2009 Microarrays have been extremely useful for investigating binding interactions among diverse types of molecular species, with the main advantage being the ability to examine many interactions using small amounts of samples and reagents. Microarrays are increasingly being used to advance research in the field of glycobiology. Several types of microarrays
Tingting, Yue, Brian B, Haab
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Towards structure-focused glycoproteomics [PDF]
Biochemical Society Transactions, 2021 Facilitated by advances in the separation sciences, mass spectrometry and informatics, glycoproteomics, the analysis of intact glycopeptides at scale, has recently matured enabling new insights into the complex glycoproteome. While diverse quantitative glycoproteomics strategies capable of mapping monosaccharide compositions of N- and O-linked glycans ...
Anastasia Chernykh +2 more
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N-glycoproteins in Plant Cell Walls: A Survey
Plants, 2022 Cell walls are an extracellular compartment specific to plant cells, which are not found in animal cells. Their composition varies between cell types, plant species, and physiological states.
Hélène San Clemente, Elisabeth Jamet
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Differential Glycosite Profiling—A Versatile Method to Compare Membrane Glycoproteomes
Molecules, 2021 Glycosylation is the most prevalent and varied form of post-translational protein modifications. Protein glycosylation regulates multiple cellular functions, including protein folding, cell adhesion, molecular trafficking and clearance, receptor ...
Malwina Michalak +8 more
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JIMD Reports, 2022 The spondylodysplastic type of Ehlers–Danlos syndrome (spEDS) is caused by genetic defects in the B4GALT7 or B3GALT6 genes both deranging the biosynthesis of the glycosaminoglycan linkage region of chondroitin/dermatan sulfate and heparan sulfate ...
Mahnaz Nikpour +7 more
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Frontiers in Immunology, 2023 The clinical success of immune-checkpoint inhibitors (ICI) in both resected and metastatic melanoma has confirmed the validity of therapeutic strategies that boost the immune system to counteract cancer.
Chad Pickering +20 more
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Glycoproteomics in neurodegenerative diseases [PDF]
Mass Spectrometry Reviews, 2009 AbstractProtein glycosylation regulates protein function and cellular distribution. Additionally, aberrant protein glycosylations have been recognized to play major roles in human disorders, including neurodegenerative diseases. Glycoproteomics, a branch of proteomics that catalogs and quantifies glycoproteins, provides a powerful means to ...
Hwang, Hyejin +17 more
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