Results 11 to 20 of about 6,118 (218)
Glycoproteomic and glycomic databases [PDF]
Clinical Proteomics, 2014 Protein glycosylation serves critical roles in the cellular and biological processes of many organisms. Aberrant glycosylation has been associated with many illnesses such as hereditary and chronic diseases like cancer, cardiovascular diseases ...
Daniel Wolozny +7 more
core +4 more sources
Clinical glycoproteomics: methods and diseases
MedCommGlycoproteins, representing a significant proportion of posttranslational products, play pivotal roles in various biological processes, such as signal transduction and immune response.
Yujia Wang +3 more
doaj +3 more sources
A Protein-Centric Strategy Coupled with Match-Between-Run Glycoproteomics Enables Discovery of Robust Site-Specific Glycan Biomarkers for Hepatocellular Carcinoma. [PDF]
Adv Sci (Weinh)In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Liu L +15 more
europepmc +2 more sources
Towards structure-focused glycoproteomics [PDF]
Biochemical Society Transactions, 2021 Facilitated by advances in the separation sciences, mass spectrometry and informatics, glycoproteomics, the analysis of intact glycopeptides at scale, has recently matured enabling new insights into the complex glycoproteome. While diverse quantitative glycoproteomics strategies capable of mapping monosaccharide compositions of N- and O-linked glycans ...
Anastasia Chernykh +2 more
openaire +2 more sources
The Hitchhiker's guide to glycoproteomics [PDF]
Biochemical Society Transactions, 2021 Protein glycosylation is one of the most common post-translational modifications that are essential for cell function across all domains of life. Changes in glycosylation are considered a hallmark of many diseases, thus making glycoproteins important diagnostic and prognostic biomarker candidates and therapeutic targets.
Tiago Oliveira +3 more
openaire +3 more sources
Targeting the glycoproteome [PDF]
Glycoconjugate Journal, 2012 Despite numerous original publications describing the structural complexity of N- and O-linked glycans on glycoproteins, only very few answer the basic question of which particular glycans are linked to which amino acid residues along the polypeptide chain.
Nilsson, Jonas +3 more
openaire +2 more sources
Glycan shield of the ebolavirus envelope glycoprotein GP
Communications Biology, 2022 Site-specific N-, O-, and C-linked glycans are characterized in the ebolavirus envelope glycoprotein GP using mass spectrometry-based glycoproteomics.
Weiwei Peng +9 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2023 N-glycosylation is a key process for various biological functions like protein folding, maturation and sorting for the conventional secretory compartment, cell-cell communication and immune response.
Cristian V. A. Munteanu +3 more
doaj +1 more source
Characterization of Cell Glycocalyx with Mass Spectrometry Methods. [PDF]
, 2019 The cell membrane plays an important role in protecting the cell from its extracellular environment. As such, extensive work has been devoted to studying its structure and function.
Lebrilla, Carlito B +3 more
core +2 more sources
Nanotechnologies in Glycoproteomics [PDF]
Clinical Proteomics, 2014 Protein glycosylation, as an important post-translational modification, is implicated in a number of ailments. Applying proteomic approaches, including mass spectrometry (MS) analyses that have played a significant role in biomarker detection and early diagnosis of diseases, to the study of glycoproteins or glycopeptides will facilitate a deeper ...
Zhao, Hu, Li, Yaojun, Hu, Ye
openaire +2 more sources