Results 161 to 170 of about 85,742 (348)

Biomaterials‐Involved Construction of Extracellular Matrices for Tumor Blockade Therapy

open access: yesExploration, EarlyView.
Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells,
Jinfeng Sun   +4 more
wiley   +1 more source

Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

open access: yesIbrain, EarlyView.
Polysaccharide‐based nanoparticles offer versatile platforms for drug delivery and immune modulation in neurodegenerative diseases. This review highlights their potential in treating Alzheimer's, Parkinson's, and multiple sclerosis, focusing on targeted delivery and neuroinflammation.
Leto‐Aikaterini Tziveleka   +5 more
wiley   +1 more source

Synthetic biology for medical biomaterials

open access: yesInterdisciplinary Medicine, EarlyView.
Synthetic biology platform has been utilized to produce a variety of medical biomaterials (MBMs), such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs), hyaluronic acid (HA), collagen (COL), poly(β‐malic acid) (PMLA), poly‐γ‐glutamic acid (γ‐PGA), alginate (ALG), chitosan (CS), bacterial cellulose (BC), and antimicrobial peptides (AMPs).
Tao Xu   +4 more
wiley   +1 more source

Statin-exposed vascular smooth muscle cells secrete proteoglycans with decreased binding affinity for LDL

open access: yesJournal of Lipid Research, 2003
Retention of LDL in the artery intima is mediated by extracellular matrix proteoglycans and plays an important role in the initiation of atherosclerosis.
C. Daniel Meyers   +3 more
doaj  

Effects of glucocorticoids on chondrocytes and cartilage [PDF]

open access: yes, 2018
OBJECTIVE: Osteoarthritis (OA) is a leading cause of disability worldwide. This disease is characterized by the inflammation and degradation of the cartilage and surrounding tissue in a joint. The disease manifests as either a result of years of wear and
Wallace, Chelsey
core  

Glycosaminoglycans Metabolism

open access: yesBiochemistry Research International, 2012
VIOLA, MANUELA   +3 more
openaire   +4 more sources

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang   +12 more
wiley   +1 more source

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