Results 61 to 70 of about 87,090 (247)

Cellular Chondroitin Sulfate and the Mucin-like Domain of Viral Glycoprotein C Promote Diffusion of Herpes Simplex Virus 1 While Heparan Sulfate Restricts Mobility

open access: yesViruses, 2022
The diffusion of viruses at the cell membrane is essential to reach a suitable entry site and initiate subsequent internalization. Although many viruses take advantage of glycosaminoglycans (GAG) to bind to the cell surface, little is known about the ...
Yara Abidine   +6 more
doaj   +1 more source

Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models

open access: yesScientific Reports, 2014
Angiogenesis, the outgrowth of blood vessels, is crucial in development, disease and regeneration. Studying angiogenesis in vitro remains challenging because the capillary morphogenesis of endothelial cells (ECs) is controlled by multiple exogenous ...
K. Chwalek   +3 more
semanticscholar   +1 more source

Dermal Glycosaminoglycans in Psoriasis

open access: yesJournal of Investigative Dermatology, 1970
Six dermal specimens from active plaques of psoriasis were subjected to biochemical analysis of glycosaminoglycans. The technique used consisted of digestion of the dermal samples with papain and trypsin, uronic acid determination by the carbazol method and identification of hyaluronic acid (HA) and dermatan sulfate (DS) by cellulose acetate ...
T. Piamphongsant   +2 more
openaire   +3 more sources

Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles

open access: yesInternational Journal of Nanomedicine, 2016
Paula Zaman,1 Julia Wang,1 Adam Blau,1 Weiping Wang,2 Tina Li,1 Daniel S Kohane,2 Joseph Loscalzo,1 Ying-Yi Zhang1 1Department of Medicine, Brigham and Women’s Hospital, 2Department of Anesthesiology, Boston Children’s Hospital, Harvard ...
Zaman P   +7 more
doaj  

Adherence of Lactobacillus salivarius to HeLa Cells Promotes Changes in the Expression of the Genes Involved in Biosynthesis of Their Ligands

open access: yesFrontiers in Immunology, 2020
The attachment of a variety of Lactobacilli to the mucosal surfaces is accomplished through the interaction of OppA, a superficial bacterial protein also involved in oligopeptide internalization, and the glycosaminoglycan moiety of the proteoglycans that
Carla Martín   +9 more
doaj   +1 more source

The Circulating Glycosaminoglycan Signature of Respiratory Failure in Critically Ill Adults*

open access: yesJournal of Biological Chemistry, 2014
Background: Endothelial glycocalyx degradation contributes to the pathogenesis of critical illness. Results: Mechanically ventilated subjects exhibited plasma glycocalyx breakdown signatures (glycosaminoglycan fragments) characteristic of direct versus ...
E. Schmidt   +7 more
semanticscholar   +1 more source

Dengue virus infection induces complement factor H but protein remains cell-associated, with changes intracellularly and in cell surface binding

open access: yesExploration of Immunology
Aim: Severe dengue is correlated with a decrease in the circulating complement regulator, factor H (FH) and prior work has shown that dengue virus (DENV) infection induces FH mRNA but not FH protein release.
Joshua G. Dubowsky   +5 more
doaj   +1 more source

Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™

open access: yesBiomolecules, 2013
Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Julie A. Leary   +2 more
doaj   +1 more source

Multiple Glycosaminoglycan-binding Epitopes of Monocyte Chemoattractant Protein-3/CCL7 Enable It to Function as a Non-oligomerizing Chemokine*

open access: yesJournal of Biological Chemistry, 2014
Background: Chemokines oligomerize upon glycosaminoglycans to establish chemokine gradients. Results: Monomeric monocyte chemoattractant protein (MCP)-3/CCL7 has a dense network of glycosaminoglycan-binding epitopes that provide sufficient affinity for ...
Catherina L. Salanga   +5 more
semanticscholar   +1 more source

Age-Related Molecular Polymorphism of the Heterodimeric Proteoglycan Bisdermican

open access: yesThe Scientific World Journal, 2004
Bisdermican (PG760) is a large, heterodimeric, dermatan sulfate proteoglycan found in selected basement membranes, smooth muscle cell layers, and different extracellular matrices.
Martin Götte   +2 more
doaj   +1 more source

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