Results 71 to 80 of about 116,862 (285)

INVESTIGATION OF ANTICOAGULATION PROPERTIES OF SULFATED GLYCOSAMINOGLYCAN MIMETICS [PDF]

, 2017
INVESTEGATION OF ANTICOAGULATION PROPERTIES OF SULFATED GLYCOSAMINOGLYCAN MIMETICS By Elsamani Ismail Abdelfadiel, MS A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University ...
Abdelfadiel, Elsamani I
core   +1 more source

Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]

, 2006
To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Corps, AN, Costa, ML, Hazleman, BL, Movin, T, Riley, GP, Robinson, AHN   +5 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Mast cell clones: a model for the analysis of cellular maturation. [PDF]

, 1982
Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H, Der Simonian, H, Dvorak, AM, Dvorak, HF, Galli, SJ, Goldin, JM, Ishizaka, T, Marcum, JA, Nabel, G, Pyne, K, Rosenberg, RD   +10 more
core   +2 more sources

Matrix Tropism Influences Endometriotic Cell Attachment Patterns

Advanced Functional Materials, EarlyView.
The influence of substrate stiffness and multicellular coculture on endometriotic cell attachment to extracellular matrix‐laden microarrayed islands is reported. This model investigates early endometriotic cell attachment, aiming to capture “lesion initiation events”.
Hannah S. Theriault, Hannah R.C. Kimmel, Alison C. Nunes, Allison L. Paxhia, Sarah Hashim, Kathryn B.H. Clancy, Gregory H. Underhill, Brendan A.C. Harley   +7 more
wiley   +1 more source

Confined compression of collagen hydrogels [PDF]

, 2013
Reconstituted collagen hydrogels are often used for in vitro studies of cell-matrix interaction and as scaffolds for tissue engineering. Understanding the mechanical and transport behaviours of collagen hydrogels is therefore extremely important, albeit ...
Busby, Grahame A., Grant, M. Helen, MacKay, Simon P., Riches, Philip E.   +3 more
core   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Overview of the Mechanisms that May Contribute to the Non-Redundant Activities of Interferon-Inducible CXC Chemokine Receptor 3 Ligands

Frontiers in Immunology, 2018
The inflammatory chemokines CXCL9, CXCL10, and CXCL11 are predominantly induced by interferon (IFN)-γ and share an exclusive chemokine receptor named CXC chemokine receptor 3 (CXCR3).
Mieke Metzemaekers, Vincent Vanheule, Rik Janssens, Sofie Struyf, Paul Proost   +4 more
doaj   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source