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Glycosaminoglycans and Neuroprotection
2011Glycosaminoglycans (GAGs) are basic building blocks of the ground substance of the extracellular matrix and present at the cellular level as an important component of the glycocalyx covering the cell membrane. In addition to the general role of GAGs in maintaining the integrity of the cell and extracellular matrix by retaining water, certain GAGs ...
B, Dudas, K, Semeniken
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Glycosaminoglycan microarrays for studying glycosaminoglycan–protein systems
Carbohydrate PolymersMore than 3000 proteins are now known to bind to glycosaminoglycans (GAGs). Yet, GAG-protein systems are rather poorly understood in terms of selectivity of recognition, molecular mechanism of action, and translational promise. High-throughput screening (HTS) technologies are critically needed for studying GAG biology and developing GAG-based ...
John E, Chittum +2 more
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Therapeutic Applications of Glycosaminoglycans
Current Medicinal Chemistry, 2006Complex polysaccharides, hyaluronic acid or hyaluronan (HA), keratan sulfate (KS), chondroitin sulfates (CSs) and heparin (Hep)/heparan sulfate (HS), are a class of ubiquitous molecules exhibiting a wide range of biological functions. They are widely distributed as glycosaminoglycans (GAGs) sidechains of proteoglycans (PGs) in the extracellular matrix ...
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Glycosaminoglycan Interaction Networks and Databases
Current Opinion in Structural Biology, 2022Sylvie Ricard-Blum, Serge Perez
exaly
Glycosaminoglycans in Tissue Engineering: A Review
Biomolecules, 2021Alyssa Panitch, Harkanwalpreet Sodhi
exaly