Results 71 to 80 of about 85,805 (344)

Norfloxacin-Loaded Electrospun Scaffolds: Montmorillonite Nanocomposite vs. Free Drug

open access: yesPharmaceutics, 2020
Infections in nonhealing wounds remain one of the major challenges. Recently, nanomedicine approach seems a valid option to overcome the antibiotic resistance mechanisms.
Angela Faccendini   +10 more
doaj   +1 more source

Melittin-Related Peptides Interfere with Sandfly Fever Naples Virus Infection by Interacting with Heparan Sulphate

open access: yesMicroorganisms, 2023
Emerging viruses pose an important global public health challenge, and early action is needed to control their spread. The Bunyaviridae family contains a great number of arboviruses which are potentially pathogenic for humans.
Annalisa Chianese   +7 more
doaj   +1 more source

Glycosaminoglycans in Scleroderma and Scleredema

open access: yesJournal of Investigative Dermatology, 1972
Skin from 6 patients with scleroderma, 3 with scleredema and 5 normal controls were subjected to qualitative and quantitative analysis of glycosaminoglycans. Glycosaminoglycans were identified by cetylpyridinium chloride-salt fractionation and by cellulose acetate electrophoresis.
Jerome S. Perlish, Raul Fleischmajer
openaire   +3 more sources

Advances in glycosaminoglycan detection

open access: yesMolecular Genetics and Metabolism, 2020
Glycosaminoglycans (GAGs) are negatively charged long linear (highly sulfated) polysaccharides consisting of repeating disaccharide units that are expressed on the surfaces of all nucleated cells. The expression of GAGs is required for embryogenesis, regulation of cell growth and proliferation, maintenance of tissue hydration, and interactions of the ...
Hironori Kobayashi   +4 more
openaire   +4 more sources

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

open access: yesAdvanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs   +17 more
wiley   +1 more source

An At-Risk Population Screening Program for Mucopolysaccharidoses by Measuring Urinary Glycosaminoglycans in Taiwan

open access: yesDiagnostics, 2019
Background: The mucopolysaccharidoses (MPSs) are a group of rare lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) and which eventually cause progressive damage to various tissues and organs.
Hsiang-Yu Lin   +11 more
doaj   +1 more source

Heparin and Heparin-Based Drug Delivery Systems: Pleiotropic Molecular Effects at Multiple Drug Resistance of Osteosarcoma and Immune Cells

open access: yesPharmaceutics, 2022
One of the main problems of modern health care is the growing number of oncological diseases both in the elderly and young population. Inadequately effective chemotherapy, which remains the main method of cancer control, is largely associated with the ...
Natalia Todosenko   +5 more
doaj   +1 more source

Dermal Glycosaminoglycans in Psoriasis

open access: yesJournal of Investigative Dermatology, 1970
Six dermal specimens from active plaques of psoriasis were subjected to biochemical analysis of glycosaminoglycans. The technique used consisted of digestion of the dermal samples with papain and trypsin, uronic acid determination by the carbazol method and identification of hyaluronic acid (HA) and dermatan sulfate (DS) by cellulose acetate ...
T. Piamphongsant   +2 more
openaire   +3 more sources

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

open access: yesAdvanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer   +8 more
wiley   +1 more source

Antithrombotics from the Sea: Polysaccharides and Beyond

open access: yesMarine Drugs, 2019
Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide ...
Francisca Carvalhal   +5 more
doaj   +1 more source

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