Results 111 to 120 of about 665,601 (180)

Expeditious Synthesis of Tri- and Tetrahydroxyazepanes from d-(−)-Quinic Acid as Potent Glycosidase Inhibitors

, 2016
Several new stereoisomers of 3,4,6-trihydroxyazepanes and 7-hydroxymethyl-3,4,5-trihydroxyazepanes as well as known 3,4,5-trihydroxyazepanes were synthesized as potent glycosidase inhibitors from d-(−)-quinic acid in an efficient manner.
Chun-Hung Lin (296934), Shiou-Ting Li (151752), Tzenge-Lien Shih (2490730), Cheng-Fan Chiang (2490733), Ru-Ying Yang (2490727)   +4 more
core   +1 more source

Expeditious Synthesis of Tri- and Tetrahydroxyazepanes from d-(−)-Quinic Acid as Potent Glycosidase Inhibitors

, 2009
Several new stereoisomers of 3,4,6-trihydroxyazepanes and 7-hydroxymethyl-3,4,5-trihydroxyazepanes as well as known 3,4,5-trihydroxyazepanes were synthesized as potent glycosidase inhibitors from D-(-)-quinic acid in an efficient manner.
Shih, Tzenge-lien; Yang, Ru-ying; Li, Shiou-ting; Chiang, Cheng-fan; Lin, Chun-hung, Shih, Tzenge-lien; Lin, Chun-hung   +1 more
core   +1 more source

Effective α-glycosidase inhibitors based on polyphenolic benzothiazole heterocycles

α-Glycosidase inhibition is one of the main approaches to treat Diabetes mellitus. Polyphenolic moieties are known to be responsible for yielding exhibit potent α-glycosidase inhibitory effects.
SEYHAN, GÖKÇE, Sevimli, Esra, Köksoy, Baybars, BARUT, BURAK, AKKAYA, DİDEM, SARI, SUAT   +5 more
core   +1 more source

Convergent, stereoselective syntheses of the glycosidase inhibitors broussonetines C, O and P

, 2009
The first syntheses of the polyhydroxylated alkaloids (iminosugars) broussonetines O and P, glycosidase inhibitors of the pyrrolidine class, have been performed in a convergent, stereocontrolled way from d-serine as the chiral starting material.
Falomir, Eva, Murga, Juan, Ribés Vidal, Celia, Marco, J. Alberto, Carda, Miguel, Celia Ribes, Miguel Carda, Juan Murga, J. Alberto Marco, Eva Falomir   +9 more
core   +1 more source

Chiron approaches to polyhydroxylated piperidines: promising glycosidase inhibitors

ARKIVOC, 2002
Dilip D. Dhavale, Vijaya N. Desai, Nabendu N. Saha, Jayant N. Tilekar   +3 more
doaj   +1 more source

From Sugars to Sugar Mimics:Stereoselective synthesis of aminocyclopentanols as glycosidase inhibitors

, 2005
The mechanism of enzymatic cleavage of glycosides has been continuously under debate and design of new glycosidase inhibitors has been based on structural similarity of putative intermediates or transition states.
Lundt, Inge
core  

Effect of α-glycosidase inhibitors from endophytic fungus Alternaria destruens on survival and development of insect pest Spodoptera litura Fab. and fungal phytopathogens. [PDF]

Sci Rep, 2019
Kaur J, Sharma A, Sharma M, Kumari Manhas R, Kaur S, Kaur A.   +5 more
europepmc   +1 more source

The chemistry of antipredator defense by secondary compounds in neotropical lepidoptera: facts, perspectives and caveats

Journal of the Brazilian Chemical Society, 2000
Chemical defense against predation in butterflies and moths has been studied since nineteenth century. A classical example is that of the larvae of the monarch butterfly Danaus plexippus, which feed on leaves of Asclepias curassavica (Asclepiadaceae ...
Trigo José R.
doaj  

Direct Stereoselective Aziridination of Cyclohexenols with 3-Amino-2-(trifluoromethyl)quinazolin-4(3H)-one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors. [PDF]

European J Org Chem, 2019
Artola M, Wouters S, Schröder SP, de Boer C, Chen Y, Petracca R, van den Nieuwendijk AMCH, Aerts JMFG, van der Marel GA, Codée JDC, Overkleeft HS.   +10 more
europepmc   +1 more source

From Mechanism-Based Retaining Glycosidase Inhibitors to Activity-Based Glycosidase Profiling. [PDF]

J Am Chem Soc
Artola M, Aerts JMFG, van der Marel GA, Rovira C, Codée JDC, Davies GJ, Overkleeft HS.   +6 more
europepmc   +1 more source