Results 91 to 100 of about 665,601 (180)

Bacterial sialidases subvert the complement system through desialylation

Protein Science, Volume 35, Issue 11, November 2026.
Abstract Bacterial sialidases (neuraminidases) are widely studied virulence factors, yet their impact on the complement system, a central component of innate immunity, remains poorly understood. Here, we investigate the effects of six sialidases from five human pathogens, including Bacteroides fragilis, Clostridium perfringens, Tannerella forsythia ...
Kurni Kurniyati, Nicholas D. Clark, Qin Fu, Sheng Zhang, Weigang Qiu, Michael G. Malkowski, Chunhao Li   +6 more
wiley   +1 more source

Anticholinergic, antidiabetic and antioxidant activities of cinnamon (cinnamomum verum) bark extracts: polyphenol contents analysis by LC-MS/MS

International Journal of Food Properties, 2019
Ethanolic (EEC) and aqueous (WEC) extracts of cinnamon (Cinnamomum verum) were evaluated for their antioxidant profiles by eight distinguished bioanalytical antioxidant methods.
Ilhami Gulcin, Ruya Kaya, Ahmet C. Goren, Hulya Akincioglu, Meryem Topal, Zeynebe Bingol, Kader Cetin Çakmak, Sevim B. Ozturk Sarikaya, Lokman Durmaz, Saleh Alwasel   +9 more
doaj   +1 more source

Design and synthesis of phenoxymethybenzoimidazole incorporating different aryl thiazole-triazole acetamide derivatives as α-glycosidase inhibitors. [PDF]

Mol Divers, 2022
Nasli Esfahani A, Iraji A, Alamir A, Moradi S, Asgari MS, Hosseini S, Mojtabavi S, Nasli-Esfahani E, Faramarzi MA, Bandarian F, Larijani B, Hamedifar H, Hajimiri MH, Mahdavi M.   +13 more
europepmc   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Synthesis of D- and L-erythro 1,5-dithiopent-1-enopyranoside sulfonium salts and their evaluation as glycosidase inhibitors

, 2009
A series of sulfonium salts derived from 1,5-dithiopent-1-enopyranosides was prepared in a three-step sequence from protected D- and L-erythrofuranoses.
Muzard, Murielle, Bello, Claudia, Plantier-Royon, Richard, Buchotte, Marie, Vogel, Pierre, Floquet, Nicolas, Murielle Muzard, Pierre Vogel, Nicolas Floquet, Richard Plantier-Royon, Marie Buchotte, Claudia Bello   +11 more
core   +1 more source

Synthesis and Cytotoxic Evaluation of 1H-1,2,3-Triazol-1-ylmethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-diones

Anais da Academia Brasileira de Ciências, 2018
The 1,2-naphthoquinone compound was previously considered active against solid tumors. Moreover, glycosidase inhibitors such as 1,2,3-1H triazoles has been pointed out as efficient compounds in anticancer activity studies.
INGRID C. CHIPOLINE, EVELYNE ALVES, PAOLA BRANCO, LETICIA V. COSTA-LOTUFO, VITOR F. FERREIRA, FERNANDO C. DA SILVA   +5 more
doaj   +1 more source

Studies on synthetic and naturally occurring glycosidase inhibitors from mushrooms. [PDF]

, 1994
Fung Pik Ha.Thesis (M.Phil.)--Chinese University of Hong Kong, 1994.Includes bibliographical references (leaves 116-121).Acknowledgments --- p.iTable of Contents --- p.iiList of Figures --- p.vList of Tables --- p.xAbstract --- p.xiChapter Chapter I

core  

Synthesis of Sulfonium Sulfate Analogues of Disaccharides and Their Conversion to Chain-Extended Homologues of Salacinol: New Glycosidase Inhibitors

, 2016
Four chain extended homologues of salacinol, a naturally occurring glycosidase inhibitor, were prepared for evaluation as inhibitors of glucosidase enzymes involved in the breakdown of carbohydrates.
Blair D. Johnston (1853404), Henrik H. Jensen (1652155), B. Mario Pinto (28519)   +2 more
core   +2 more sources

Features of low-temperature storage of streptomyces strains - producers of glycosidaz inhibitors

Пищевые системы, 2019
The aim of the work is to study the inhibitory activity of the Streptomyces lucensis VKPM Ac-1743 and Streptomyces violaceus VKPM Ac-1734 strains stored at –18 °C in a 15 % glycerol solution and in a 0.9 % sodium chloride solution.The object of the study
A. A. Printseva, N. Yu. Sharova, T. V. Vybornova, B. S. Manzhieva   +3 more
doaj   +1 more source

Structural studies of the beta-glycosidase from Sulfolobus solfataricus in complex with covalently and noncovalently bound inhibitors

, 2004
Transition-state mimicry is increasingly important both to understand enzyme mechanism and to direct the synthesis of putative therapeutic agents. X-ray crystallography is able to provide vital information on the interactions between an enzyme and the ...
Ducros, V M A, PERUGINO, GIUSEPPE, Ducros, Valérie M. A, Hoos, R, Vasella, A, Hoos, Roland, ROSSI, MOSE', Gloster, T M, Roberts, Shirley, MORACCI, Marco, Roberts, S, Vasella, Andrea, Davies, Gideon J., Davies, G J, Moracci, M, Gloster, Tracey M, Rossi, M, Perugino, G, Moracci M, Gloster TM, Roberts S, Rossi M, Davies GJ, Hoos R, Perugino G, Ducros VM, Vasella A   +26 more
core   +1 more source