Results 41 to 50 of about 665,601 (180)

Microwave-Assisted Synthesis of Andrographolide Analogues as Potent β-Glycosidase Inhibitors

open access: yesSynOpen, 2018
Andrographolide, a bioactive compound isolated from Andrographis paniculata exhibits multiple pharmacological activities, including anti-HIV, antiplatelet aggregation, hepatic lipid peroxidation protective, hepatoprotective, choleretic, and anticancer ...
Masood ur Rahman   +4 more
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

open access: yesAnimal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen   +7 more
wiley   +1 more source

Exploring architectures displaying multimeric presentations of a trihydroxypiperidine iminosugar

open access: yesBeilstein Journal of Organic Chemistry, 2015
The synthesis of new multivalent architectures based on a trihydroxypiperidine α-fucosidase inhibitor is reported herein. Tetravalent and nonavalent dendrimers were obtained by means of the click chemistry approach involving the copper azide-alkyne ...
Camilla Matassini   +5 more
doaj   +1 more source

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra   +4 more
wiley   +1 more source

Synthesis of Halogenated-4-Nitrophenyl 2-deoxy-2-halogeno-pyranosides via -Halogenosuccinimide Activated Glucal

open access: yesNatural Product Communications, 2018
Reaction of 3,4,6-tri- O -acetyl-D-glucal with silver 4-nitrophenolate in the presence of N -iodosuccinimide and N -bromosuccinimide produced (2,6-dihalo-4-nitro)phenyl 2-halo-2-deoxy-α-D-glycopyranosides.
Chieri Inoue   +4 more
doaj   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

open access: yesChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi   +2 more
wiley   +1 more source

Post-print de Current Chemical Biosynthetic Pathways to Glycosidase Inhibitors

open access: yes, 2020
Glycosidase inhibitors are important compounds that can interfere with ...
Tomás Tejero   +3 more
core  

Evaluation of biochemical and histological indices of the pulp intactix teeth in the experimental conditions pulphyperthermia

open access: yesКубанский научный медицинский вестник, 2014
The article presents the results of experimental studies on the activity of acid lysosomal field of glycosidase inhibition (β-glucuronidase, β-glucosidase and β-N-acetylglucosaminidase) and their influence on the function of cells of the pulp in the ...
A. G. Sirak   +5 more
doaj  

Effects of Sponge-Derived Alkaloids on Activities of the Bacterial α-D-Galactosidase and Human Cancer Cell α-N-Acetylgalactosaminidase

open access: yesBiomedicines, 2021
During a search for glycosidase inhibitors among marine natural products, we applied an integrated in vitro and in silico approach to evaluate the potency of some aaptamines and makaluvamines isolated from marine sponges on the hydrolyzing activity of α ...
Natalia Utkina   +6 more
doaj   +1 more source

Dietary Artificial Sweeteners: From Chemical Transformation in Food to Gut Microbial Processing

open access: yesChemFoodChem, EarlyView.
This review article unites classical and recent findings on the stability of artificial sweeteners in food. The focus is on ten sweeteners approved in the European Union: their chemical stability during processing and storage, individual degradation products, and their interactions with the intestinal microbiota.
Jürgen Lassak, Michael Hellwig
wiley   +1 more source

Home - About - Disclaimer - Privacy