Results 31 to 40 of about 15,361 (204)

How a Glycoside Hydrolase Recognizes a Helical Polyglucan [PDF]

Structure, 2017
Similarly to other biopolymers, linear polysaccharides can form double- or triple-helical structures. How enzymes recognize and manage this quaternary structure is an unresolved question. In this issue of Structure, Pluvinage et al. (2017) shed light on the structural complementarity between family GH81 glycoside hydrolase and the quaternary structure ...
Bernard Henrissat, Bernard Henrissat, Bernard Henrissat, Marie-Line Garron, Marie-Line Garron   +4 more
openaire   +4 more sources

Curation of characterized glycoside hydrolases of Fungal origin [PDF]

Database, 2011
Fungi produce a wide range of extracellular enzymes to break down plant cell walls, which are composed mainly of cellulose, lignin and hemicellulose. Among them are the glycoside hydrolases (GH), the largest and most diverse family of enzymes active on these substrates.
Murphy, Caitlin, Powlowski, Justin, Wu, Min, Butler, Greg, Tsang, Adrian   +4 more
openaire   +4 more sources

Transcriptome Profiling-Based Analysis of Carbohydrate-Active Enzymes in Aspergillus terreus Involved in Plant Biomass Degradation

Frontiers in Bioengineering and Biotechnology, 2020
Given the global abundance of plant biomass residues, potential exists in biorefinery-based applications with lignocellulolytic fungi. Frequently isolated from agricultural cellulosic materials, Aspergillus terreus is a fungus efficient in secretion of ...
Camila L. Corrêa, Glaucia E. O. Midorikawa, Edivaldo Ximenes Ferreira Filho, Eliane Ferreira Noronha, Gabriel S. C. Alves, Roberto Coiti Togawa, Orzenil Bonfim Silva-Junior, Marcos Mota do Carmo Costa, Priscila Grynberg, Robert N. G. Miller   +9 more
doaj   +1 more source

Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome. [PDF]

PLoS ONE, 2013
Distal gut bacteria play a pivotal role in the digestion of dietary polysaccharides by producing a large number of carbohydrate-active enzymes (CAZymes) that the host otherwise does not produce.
Abdessamad El Kaoutari, Fabrice Armougom, Quentin Leroy, Bernard Vialettes, Matthieu Million, Didier Raoult, Bernard Henrissat   +6 more
doaj   +1 more source

Identification of d-arabinan-degrading enzymes in mycobacteria

Nature Communications, 2023
Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that cleave the d-arabinan core of arabinogalactan, an unusual component of the cell wall of ...
Omar Al-Jourani, Samuel T. Benedict, Jennifer Ross, Abigail J. Layton, Phillip van der Peet, Victoria M. Marando, Nicholas P. Bailey, Tiaan Heunis, Joseph Manion, Francesca Mensitieri, Aaron Franklin, Javier Abellon-Ruiz, Sophia L. Oram, Lauren Parsons, Alan Cartmell, Gareth S. A. Wright, Arnaud Baslé, Matthias Trost, Bernard Henrissat, Jose Munoz-Munoz, Robert P. Hirt, Laura L. Kiessling, Andrew L. Lovering, Spencer J. Williams, Elisabeth C. Lowe, Patrick J. Moynihan   +25 more
doaj   +1 more source

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]

Open Biology, 2016
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Glyn R. Hemsworth, Andrew J. Thompson, Judith Stepper, Łukasz F. Sobala, Travis Coyle, Johan Larsbrink, Oliver Spadiut, Ethan D. Goddard-Borger, Keith A. Stubbs, Harry Brumer, Gideon J. Davies   +10 more
doaj   +1 more source

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature Communications, 2018
Mechanism-based inhibitors of glycoside hydrolases are useful probes for basic research and represent potential drug candidates. Here, the authors present a series of mechanism-based covalent α-galactosidase inhibitors and elucidate the kinetic and ...
Weiwu Ren, Robert Pengelly, Marco Farren-Dai, Saeideh Shamsi Kazem Abadi, Verena Oehler, Oluwafemi Akintola, Jason Draper, Michael Meanwell, Saswati Chakladar, Katarzyna Świderek, Vicent Moliner, Robert Britton, Tracey M. Gloster, Andrew J. Bennet   +13 more
doaj   +1 more source

Discovery of a Kojibiose Hydrolase by Analysis of Specificity-Determining Correlated Positions in Glycoside Hydrolase Family 65

Molecules, 2021
The Glycoside Hydrolase Family 65 (GH65) is an enzyme family of inverting α-glucoside phosphorylases and hydrolases that currently contains 10 characterized enzyme specificities. However, its sequence diversity has never been studied in detail.
Emma De Beul, Alana Jongbloet, Jorick Franceus, Tom Desmet   +3 more
doaj   +1 more source

Purification of glycoside hydrolases from Bacteroides fragilis [PDF]

Applied and Environmental Microbiology, 1980
Six glycoside hydrolases in the culture medium of Bacteroides fragilis--alpha-glucosidase, beta-glucosidase, alpha-galactosidase, beta-galactosidase, beta-N-acetylglucosaminidase, and alpha-L-fucosidase-were systematically purified by ammonium sulfate precipitation, gel filtration chromatography, and density gradient isoelectric focusing.
J O Berg, L Lindqvist, C E Nord
openaire   +3 more sources

A glucotolerant β-glucosidase from the fungus Talaromyces amestolkiae and its conversion into a glycosynthase for glycosylation of phenolic compounds

Microbial Cell Factories, 2020
Background The interest for finding novel β-glucosidases that can improve the yields to produce second-generation (2G) biofuels is still very high. One of the most desired features for these enzymes is glucose tolerance, which enables their optimal ...
Juan Antonio Méndez-Líter, Manuel Nieto-Domínguez, Beatriz Fernández de Toro, Andrés González Santana, Alicia Prieto, Juan Luis Asensio, Francisco Javier Cañada, Laura Isabel de Eugenio, María Jesús Martínez   +8 more
doaj   +1 more source