Results 41 to 50 of about 28,465 (236)

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]

Open Biology, 2016
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Glyn R. Hemsworth, Andrew J. Thompson, Judith Stepper, Łukasz F. Sobala, Travis Coyle, Johan Larsbrink, Oliver Spadiut, Ethan D. Goddard-Borger, Keith A. Stubbs, Harry Brumer, Gideon J. Davies   +10 more
doaj   +1 more source

Uncovering the molecular mechanisms of lignocellulose digestion in shipworms [PDF]

, 2018
Lignocellulose forms the structural framework of woody plant biomass and represents the most abundant carbon source in the biosphere. Turnover of woody biomass is a critical component of the global carbon cycle, and the enzymes involved are of increasing
Bates, Rachel, Besser, Katrin, Bruce, Neil Charles, Cragg, Simon M., Dowle, Adam, Elias, Luisa, Li, Yi, McQueen Mason, Simon John, Pesante, Giovanna, Rathbone, Deborah Ann, Sabbadin, Federico, Shipway, J Reuben, Stark, Meg, Steele-King, Clare G.   +13 more
core   +3 more sources

GH97 is a new family of glycoside hydrolases, which is related to the α-galactosidase superfamily

BMC Genomics, 2005
Background As a rule, about 1% of genes in a given genome encode glycoside hydrolases and their homologues. On the basis of sequence similarity they have been grouped into more than ninety GH families during the last 15 years.
Naumoff Daniil G
doaj   +1 more source

Hydration of vinyl ether groups by unsaturated glycoside hydrolases and their role in bacterial pathogenesis [PDF]

, 2008
Many pathogenic microorganisms invade mammalian and/or plant cells by producing polysaccharide-degrading enzymes (lyases and hydrolases). Mammalian glycosaminoglycans and plant pectins that form part of the cell surface matrix are typical targets for ...
Bunzo Mikami, Kousaku Murata, Takafumi Itoh, Wataru Hashimoto, Yukie Maruyama   +4 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Ratoon Season Rice Reduces Methane Emissions by Limiting Acetic Acid Transport to the Rhizosphere and Inhibiting Methanogens

Advanced Science, EarlyView.
This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou, Hailong Xu, Bin Qin, Chaojie Lan, Jinying Li, Bianhong Zhang, Huabin Zhang, Chunlin Guo, Hongfei Chen, Zhongming Fang, Quanzhi Zhao, Wenfei Wang, Changxun Fang, Zhixing Zhang, Wenxiong Lin   +14 more
wiley   +1 more source

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

Nature Communications, 2018
Mechanism-based inhibitors of glycoside hydrolases are useful probes for basic research and represent potential drug candidates. Here, the authors present a series of mechanism-based covalent α-galactosidase inhibitors and elucidate the kinetic and ...
Weiwu Ren, Robert Pengelly, Marco Farren-Dai, Saeideh Shamsi Kazem Abadi, Verena Oehler, Oluwafemi Akintola, Jason Draper, Michael Meanwell, Saswati Chakladar, Katarzyna Świderek, Vicent Moliner, Robert Britton, Tracey M. Gloster, Andrew J. Bennet   +13 more
doaj   +1 more source

Proteome readjustments in the apoplastic space of Arabidopsis thaliana ggt1 mutant leaves exposed to UV-B radiation [PDF]

, 2015
Ultraviolet-B radiation acts as an environmental stimulus, but in high doses it has detrimental effects on plant metabolism. Plasma membranes represent a major target for ROS generated by this harmful radiation.
ARRIGONI, GIORGIO, FABREGA PRATS, MARTA, GIARETTA, SABRINA, Leonard Ebinezer Barnabas, MASI, ANTONIO, PIVATO, MICAELA, PRASAD, DINESH, Syed M. M. Mehdi, TRENTIN, ANNA RITA   +8 more
core   +2 more sources

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Gut Microbe‐Driven Resistance Mechanisms in Propylea Japonica: Insights from Horizontal Gene Transfer and Oxidative Phosphorylation

Advanced Science, EarlyView.
Acinetobacter regulates dinotefuran tolerance in Propylea japonica by mediating the expression of the horizontally transferred gene PjDUF1. Abstract Insect–microbial symbiont relationships are widespread in nature and often involve lateral gene transfer.
Ningbo HuangFu, Xiangzhen Zhu, Zhijuan Tang, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Jinjie Cui, Zhaojiang Guo, Junyu Luo, Xueke Gao   +10 more
wiley   +1 more source