Results 181 to 190 of about 26,122 (235)

[Biosynthesis of glycosphingolipids].

Postepy biochemii, 1985
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Glycosphingolipids and atherosclerosis

, 2013
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A novel inositol-containing glycosphingolipid isolated from human peripheral nerve [PDF]

FEBS Letters, 1991
An inositol-phosphate-containing glycosphingolipid, not reported earlier, was isolated from human cauda equina. Structural characterization showed the glycosphingolipid to be inosital-phosphoryl-2(3) galactosylceramide.
Jan-Eric Mansson, J E Mansson, Britt-Marie Rynmark   +2 more
exaly   +2 more sources

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Glycosphingolipids

2021
Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology.In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this ...
Elena, Chiricozzi, Massimo, Aureli, Laura, Mauri, Erika, Di Biase, Giulia, Lunghi, Maria, Fazzari, Manuela, Valsecchi, Emma Veronica, Carsana, Nicoletta, Loberto, Alessandro, Prinetti, Sandro, Sonnino   +10 more
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Salvage pathways in glycosphingolipid metabolism

Biochimie, 2003
In this review, the focus is on the role of salvage pathways in glycosphingolipid, particularly, ganglioside metabolism. Ganglioside de novo biosynthesis, that begins with the formation of ceramide and continues with the sequential glycosylation steps ...
Rosaria Bassi, Laura Riboni, Paola Viani
exaly   +2 more sources

Glycosphingolipids and Insulin Resistance

2011
Glycosphingolipids are structural membrane components, residing largely in the plasma membrane with their sugar-moieties exposed at the cell's surface. In recent times a crucial role for glycosphingolipids in insulin resistance has been proposed. A chronic state of insulin resistance is a rapidly increasing disease condition in Western and developing ...
Aerts, J.M., Boot, R.G., van Eijk, M., Groener, J., Bijl, N., Lombardo, E., Bietrix, F.M., Dekker, N., Groen, A.K., Ottenhof, M., Roomen, C., Aten, J., Serlie, M., Langeveld, M., Wennekes, T., Overkleeft, H.S.   +15 more
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Glycosphingolipid lysosomal storage diseases: therapy and pathogenesis

Neuropathology and Applied Neurobiology, 2002
Paediatric neurodegenerative diseases are frequently caused by inborn errors in glycosphingolipid (GSL) catabolism and are collectively termed the glycosphingolipidoses.
Frances Platt
exaly   +2 more sources

Glycosphingolipids and cell death

Glycoconjugate Journal, 2003
Sphingolipids have been implicated in various cellular processes including growth, cell-cell or ligand-receptor interactions, and differentiation. In addition to their importance as reservoirs of metabolites with important signaling properties, sphingolipids also help provide structural order to plasma membrane lipids and proteins within the bilayer ...
Meryem, Bektas, Sarah, Spiegel
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HPLC of Glycosphingolipids and Phospholipids

2021
This chapter reviews HPLC methodology developed for the analysis of the glycosphingolipids and phospholipids, which are ubiquitious components of biological membranes. The isolation and measurement of glycosphingolipids and phospholipids are essential for many studies on complex biological systems.
R H, McCluer, M D, Ullman, F B, Jungalwala   +2 more
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Biochemistry of glycosphingolipid degradation

Clinica Chimica Acta, 1997
Glycosphingolipids (GSLs) form cell-type-specific patterns on the surface of eukaryotic cells. Degradation of GSLs requires endocytotic membrane flow of plasma membrane-derived GSLs into the lysosomes as the digesting organelles. Recent research focused on the mechanisms leading to selective membrane degradation in the lysosomes and on the mechanism ...
K, Sandhoff, T, Kolter
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