Results 41 to 50 of about 26,122 (235)

Glycosphingolipids: synthesis and functions [PDF]

FEBS Journal, 2013
Glycosphingolipids (GSLs) comprise a heterogeneous group of membrane lipids formed by a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans can be linked to tens of different ceramide molecules, giving rise to an astonishing variety of structurally different compounds, each of which has the potential for a specific ...
D'Angelo G, Capasso S, Sticco L, Russo D
openaire   +2 more sources

glycosphingolipid biosynthesis-html

, 2014
unigenes mapped to glycosphingolipid ...
Karen Fugate (480954)
core   +1 more source

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide. [PDF]

, 2005
peer reviewedAlzheimer disease is associated with extracellular deposits of amyloid beta-peptides in the brain. Amyloid beta-peptides are generated by proteolytic processing of the beta-amyloid precursor protein by beta- and gamma-secretases.
Sandhoff, Konrad, Walter, Jochen, HENEKA, Michael, Prager, Kai, Tamboli, Irfan Y, Barth, Esther   +5 more
core   +1 more source

ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species

Journal of Lipid Research, 2021
The cytosolic-oriented glucosylceramide (GlcCer) synthase is enigmatic, requiring nascent GlcCer translocation to the luminal Golgi membrane to access glycosphingolipid (GSL) anabolic glycosyltransferases. The mechanism by which GlcCer is flipped remains
Monique Budani, Christiane Auray-Blais, Clifford Lingwood   +2 more
doaj   +1 more source

glycosphingolipid biosynthesis-ganglio series

, 2014
unigenes mapped to glycosphingolipid biosynthesis-ganglio ...
Karen Fugate (480954)
core   +1 more source

glycosphingolipid biosynthesis-ganglio series-html

, 2014
unigenes mapped to glycosphingolipid biosynthesis-ganglio ...
Karen Fugate (480954)
core   +1 more source

Glycosphingolipid antigens and cancer therapy [PDF]

, 1997
Specific types of glycosphingolipid (GSL), which are chemically detectable in normal cells, are more highly expressed in tumors. The high level of expression on the surfaces of tumor cells causes an antibody response to these GSLs, which can therefore be
Zhang, Yongmin, Sen-Itiroh Hakomori, Hakomori, Sen-Itiroh, Yongmin Zhang   +3 more
core   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Shock Waves Enhance Expression of Glycosphingolipid Tumor Antigen on Renal Cell Carcinoma: Dynamics of Physically Unmasking Hidden Intracellular Markers Independent of Gene-Signaling Pathways

Biomedicines, 2022
Antigens associated with tumors have proven valuable in cancer immunotherapy. Their insufficient expression in the majority of tumors, however, limits their potential value as therapeutic markers.
Nushin Hosano, Zahra Moosavi-Nejad, Makoto Satoh, Hamid Hosano   +3 more
doaj   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source