Abstract Glomerular podocytes play a key role in the pathogenesis of diabetic kidney disease (DKD). Recent studies suggest that natriuretic peptides (NPs) are podocyte protective. The beneficial effects of NPs are inhibited by the removal of NPs from the circulation by the NP clearance receptor (NPRC).
Liming Wang +4 more
wiley +1 more source
Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade +2 more
wiley +1 more source
Engineering and evaluation of precision-glycosylated clickable albumin nanoplatform for targeting the tumor microenvironment. [PDF]
Park JY +11 more
europepmc +1 more source
Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology
Two proposed sequence of events for thyroxine formation in patients expressing mutant thyroglobulin. (A) (1) TSH stimulation drives expression of misfolded TG. (2) Unremitting ER stress. (3) Stress‐induced cell death. (4) Dead thyrocytes release their contents. (5) The contents become iodinated. (6) Forming thyroxine.
Crystal Young, Peter Arvan
wiley +1 more source
Lactate dehydrogenase-to-albumin ratio for the severity of coronary artery disease in acute myocardial infarction: A retrospective study. [PDF]
Wu H, Wu Z, Xin Y, Jiang X, Guo C.
europepmc +1 more source
Predictive role and clinical correlation of copeptin in patients with type 2 diabetes mellitus associated nephropathy approaching end-stage renal disease. [PDF]
Noor T, Kiran Z, Khan MT, Hanif F.
europepmc +1 more source
Protein deglycosylation can drastically affect the cellular uptake [PDF]
Ghazaryan, A. +2 more
core +2 more sources
Association Between Abdominal Obesity and Hyperuricemia in Peruvian Adults with Type 2 Diabetes Mellitus. [PDF]
Peralta-Vera FG +5 more
europepmc +1 more source
Albumin orchestrates a natural host defence mechanism against mucormycosis. [PDF]
Pikoulas A +40 more
europepmc +1 more source
Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy. [PDF]
Fukao Y +9 more
europepmc +1 more source

