Results 151 to 160 of about 52,375 (251)

Podocyte specific knockout (KO) of the natriuretic peptide clearance receptor (NPRC) attenuates diabetic kidney disease (DKD)

open access: yesPhysiological Reports, Volume 14, Issue 9, May 2026.
Abstract Glomerular podocytes play a key role in the pathogenesis of diabetic kidney disease (DKD). Recent studies suggest that natriuretic peptides (NPs) are podocyte protective. The beneficial effects of NPs are inhibited by the removal of NPs from the circulation by the NP clearance receptor (NPRC).
Liming Wang   +4 more
wiley   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade   +2 more
wiley   +1 more source

Engineering and evaluation of precision-glycosylated clickable albumin nanoplatform for targeting the tumor microenvironment. [PDF]

open access: yesTheranostics
Park JY   +11 more
europepmc   +1 more source

Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Two proposed sequence of events for thyroxine formation in patients expressing mutant thyroglobulin. (A) (1) TSH stimulation drives expression of misfolded TG. (2) Unremitting ER stress. (3) Stress‐induced cell death. (4) Dead thyrocytes release their contents. (5) The contents become iodinated. (6) Forming thyroxine.
Crystal Young, Peter Arvan
wiley   +1 more source

Association Between Abdominal Obesity and Hyperuricemia in Peruvian Adults with Type 2 Diabetes Mellitus. [PDF]

open access: yesClin Med Insights Endocrinol Diabetes
Peralta-Vera FG   +5 more
europepmc   +1 more source

Albumin orchestrates a natural host defence mechanism against mucormycosis. [PDF]

open access: yesNature
Pikoulas A   +40 more
europepmc   +1 more source

Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy. [PDF]

open access: yesNephrol Dial Transplant
Fukao Y   +9 more
europepmc   +1 more source

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