Results 151 to 160 of about 175,061 (321)
Interference with glycosylation of glycoproteins. Inhibition of formation of lipid-linked oligosaccharides in vivo [PDF]
, 1979 R. Datema, Ralph Τ. Schwarz
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Contemporary Perspectives on Chronic Renal Disorders
Chronic Diseases and Translational Medicine, EarlyView.ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok +5 more
wiley +1 more source
Macromolecular Bioscience, Volume 22, Issue 12, December 2022., 2022 The combination of solid phase polymer synthesis and enzymatic sialyation is used to yield multivalent stereoselective 3′‐sialyllactose‐presenting macromolecules. The one pot reaction using synthetase NmCSS and sialyltransferase PmST1 is suitable to transfer sialic acid to either glycan acceptors, such as lactose, but as shown now in this study also to
Patrick B. Konietzny +6 more
wiley +1 more source
Glucodensity Functional Profiles Outperform Traditional Continuous Glucose Monitoring Metrics [PDF]
arXivContinuous glucose monitoring (CGM) data has revolutionized the management of type 1 diabetes, particularly when integrated with insulin pumps to mitigate clinical events such as hypoglycemia. Recently, there has been growing interest in utilizing CGM devices in clinical studies involving healthy and diabetes populations.
arxiv
Formation of 2-Deoxyglucose-Containing Lipid-Linked Oligosaccharides. Interference with Glycosylation of Glycoproteins [PDF]
, 1978 R. Datema, Ralph Τ. Schwarz
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Chemistry – A European Journal, EarlyView.Staphylococcus aureus serotype 1 is a highly virulent pathogen and the capsular polysaccharide (CP1) has been shown to play an important role in virulence and be a target for opsonic antibodies. We here describe the synthesis of a set of CP1 oligosaccharides, varying in length and with different taurination patterns. Abstract Staphylococcus aureus is a
Kitt Emilie Østerlid +4 more
wiley +1 more source
A general language model for peptide identification [PDF]
arXivAdvances in peptide identification are revolutionizing our ability to decipher protein functions and accelerate therapeutic discovery. We present PDeepPP, a deep learning framework that integrates pretrained protein language models with parallel transformer-CNN architectures, achieving state-of-the-art performance in peptide characterization tasks. The
arxiv
Carbohydrate Synthesis is Entering the Data‐Driven Digital Era
Chemistry – A European Journal, EarlyView.The outcome of glycosylations, essential for glycochemistry, is difficult to predict due to its intricate mechanism and the influence of protective groups. Recent advances illustrate that integrating digital tools like automation, computational modelling, and data management drives progress in the carbohydrate synthesis field.
Eric T. Sletten +3 more
wiley +1 more source
The Orthoester Glycosylation Method. Variations in the Anomeric Composition of the Product with Aglycone Basicity in the Two-Step Procedure. [PDF]
, 1976 Per J. Garegg +5 more
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Rapid Stereochemical Analysis of Glycosylations in Flow by Ion Mobility Spectrometry
Chemistry – A European Journal, EarlyView.Glycans are complex molecules that are challenging to synthesize and analyze due to their diverse structures. Stereoselective glycosylation is crucial for efficient synthesis, influenced by activators, leaving groups, solvents, temperature, and concentration.
Jakob B. Wolf +11 more
wiley +1 more source