Results 11 to 20 of about 175,061 (321)

Survival of the glycosylated

open access: yeseLife, 2021
Osteocalcin is a bone matrix protein that acts like a hormone when it reaches the blood, and has different effects in mice and humans.
Harry C Blair, Paul H Schlesinger
openaire   +4 more sources

Differential Effects of D-Galactose Supplementation on Golgi Glycosylation Defects in TMEM165 Deficiency

open access: yesFrontiers in Cell and Developmental Biology, 2022
Glycosylation is a ubiquitous and universal cellular process in all domains of life. In eukaryotes, many glycosylation pathways occur simultaneously onto proteins and lipids for generating a complex diversity of glycan structures.
Zoé Durin   +7 more
doaj   +1 more source

Involvement of ST6Gal I‐mediated α2,6 sialylation in myoblast proliferation and differentiation

open access: yesFEBS Open Bio, 2020
Myogenesis is a physiological process which involves the proliferation of myoblasts and their differentiation into multinucleated myotubes, which constitute the future muscle fibers.
Caroline Vergé   +5 more
doaj   +1 more source

Opportunities and Challenges of Bacterial Glycosylation for the Development of Novel Antibacterial Strategies

open access: yesFrontiers in Microbiology, 2021
Glycosylation is a ubiquitous process that is universally conserved in nature. The various products of glycosylation, such as polysaccharides, glycoproteins, and glycolipids, perform a myriad of intra- and extracellular functions.
Liubov Yakovlieva   +2 more
doaj   +1 more source

Innovative Metrics for Reporting and Comparing the Glycan Structural Profile in Biotherapeutics

open access: yesMolecules, 2023
Glycosylation is a critical quality attribute in biotherapeutics, impacting properties such as protein stability, solubility, clearance rate, efficacy, immunogenicity, and safety.
Renato Mastrangeli   +2 more
doaj   +1 more source

Glycosylation of viral proteins: Implication in virus–host interaction and virulence

open access: yesVirulence, 2022
Glycans are among the most important cell molecular components. However, given their structural diversity, their functions have not been fully explored. Glycosylation is a vital post-translational modification for various proteins.
Tingting Feng   +6 more
doaj   +1 more source

Glycosylation modification patterns reveal distinct tumor metabolism and immune microenvironment landscape in lower-grade gliomas

open access: yesFrontiers in Cell and Developmental Biology, 2022
Glycosylation alterations, a key driver throughout tumorigenesis and tumor progression, could regulate the microenvironment and immune response as well as lead to harmful metabolism and cell signaling.
Guihua Tang   +3 more
doaj   +1 more source

Intramolecular glycosylation [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2017
Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major hurdle that chemists experience.
Xiao G. Jia, Alexei V. Demchenko
openaire   +3 more sources

Patient and observer reported outcome measures to evaluate health-related quality of life in inherited metabolic diseases: a scoping review

open access: yesOrphanet Journal of Rare Diseases, 2018
Background Health-related Quality of Life (HrQoL) is a multidimensional measure, which has gained clinical and social relevance. Implementation of a patient-centred approach to both clinical research and care settings, has increased the recognition of ...
Carlota Pascoal   +8 more
doaj   +1 more source

Glycosylation of HDL-Associated Proteins and Its Implications in Cardiovascular Disease Diagnosis, Metabolism and Function

open access: yesFrontiers in Cardiovascular Medicine, 2022
High-density lipoprotein (HDL) particles, long known for their critical role in the prevention of cardiovascular disease (CVD), were recently identified to carry a wide array of glycosylated proteins, and the importance of this glycosylation in the ...
Eduardo Z. Romo, Angela M. Zivkovic
doaj   +1 more source

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