Results 11 to 20 of about 406,798 (331)
Glycosylation of viral proteins: Implication in virus–host interaction and virulence
Virulence, 2022 Glycans are among the most important cell molecular components. However, given their structural diversity, their functions have not been fully explored. Glycosylation is a vital post-translational modification for various proteins.
Tingting Feng +6 more
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Glycosylation and behavioral symptoms in neurological disorders
Translational Psychiatry, 2023 Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is a complex post-translational modification that plays a crucial role in cellular function.
Prajitha Pradeep +2 more
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Computational analysis reveals non-consensus N-glycosylation sequons in antibody Fab region [PDF]
mAbsProtein glycosylation at asparagine typically occurs at a consensus motif. However, recent studies have reported instances of N-glycosylation at non-consensus sites, though the mechanisms and implications of these atypical modifications remain unclear ...
Baiyu Qiu +3 more
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Glycosylation in neuroinflammation: mechanisms, implications, and therapeutic strategies for neurodegenerative diseases [PDF]
Translational NeurodegenerationNeuroinflammation is a key pathological mechanism underlying neurodegenerative diseases, and intricately interacts with protein glycosylation. Emerging evidence suggests that aberrant glycosylation disrupts immune homeostasis, activates microglia, and ...
Shenglan Cheng, Bo Xiao, Zhaohui Luo
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The Intersection of Glycosylation and Ferroptosis in Cancer [PDF]
AntioxidantsFerroptosis, an iron-dependent form of regulated cell death characterized by lipid peroxidation, has emerged as a critical mechanism in cancer biology and therapy.
Jihan Kim, Junghyun Kim, Man S. Kim
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Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases [PDF]
Gastroenterology, 2020 Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate their structure and function. Glycans modify proteins required for regulation of immune cells, and alterations have been associated with inflammatory conditions.
Callewaert, Nico +6 more
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O-GlcNAcylation of RIPK1 rescues red blood cells from necroptosis
Frontiers in Immunology, 2023 Necroptosis is a type of cell death with excessive inflammation and organ damage in various human diseases. Although abnormal necroptosis is common in patients with neurodegenerative, cardiovascular, and infectious diseases, the mechanisms by which O ...
Junghwa Seo +16 more
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Role of Sialyl-O-Acetyltransferase CASD1 on GD2 Ganglioside O-Acetylation in Breast Cancer Cells
Cells, 2021 The O-acetylated form of GD2, almost exclusively expressed in cancerous tissues, is considered to be a promising therapeutic target for neuroectoderm-derived tumors, especially for breast cancer.
Sumeyye Cavdarli +8 more
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Frontiers in Immunology, 2021 Post-translational modifications, including O-GlcNAcylation, play fundamental roles in modulating cellular events, including transcription, signal transduction, and immune signaling.
Junghwa Seo +24 more
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Biomedicines, 2022 Non-alcoholic fatty liver disease (NAFLD) is the major cause of chronic liver disease, yet cost-effective and non-invasive diagnostic tools to monitor the severity of the disease are lacking.
Kwang Seob Lee +6 more
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