Results 21 to 30 of about 175,484 (260)
Glycosylation and behavioral symptoms in neurological disorders
Translational Psychiatry, 2023 Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is a complex post-translational modification that plays a crucial role in cellular function.
Prajitha Pradeep +2 more
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Current Research in Pharmacology and Drug Discovery, 2022 Dysregulated surface glycoproteins play an important role in tumor cell proliferation and progression. Abnormal glycosylation of these glycoproteins may activate tumor signal transduction and lead to tumor development.
Ziyuan Gao +6 more
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Intramolecular glycosylation [PDF]
Beilstein Journal of Organic Chemistry, 2017 Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major hurdle that chemists experience.
Xiao G. Jia, Alexei V. Demchenko
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Linchuang shenzangbing zazhi, 2021 As one of the most important post-translational modifications, glycosylation plays a significant role in the functions of proteins.N-glycosylation exerts critical effects in different biological processes among various forms of glycosylation, whereas ...
任伟夫, 边琪
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Glycosylation site alteration in the evolution of influenza A (H1N1) viruses. [PDF]
PLoS ONE, 2011 Influenza virus typically alters protein glycosylation in order to escape immune pressure from hosts and hence to facilitate survival in different host environments.
Shisheng Sun +4 more
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Frontiers in Cellular and Infection Microbiology, 2018 The major structural envelope (E) protein of Japanese encephalitis virus (JEV) facilitates cellular binding/entry and is the primary target of neutralizing antibodies.
Jian-Jong Liang +3 more
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Quantitative Analyses Reveal Novel Roles for
mBio, 2019 In eukaryotes, glycosylation plays a role in proteome stability, protein quality control, and modulating protein function; however, similar studies in bacteria are lacking.
Sherif Abouelhadid +8 more
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Cold Spring Harbor Perspectives in Biology, 2011 Glycosylation is a very common modification of protein and lipid, and most glycosylation reactions occur in the Golgi. Although the transfer of initial sugar(s) to glycoproteins or glycolipids occurs in the ER or on the ER membrane, the subsequent addition of the many different sugars that make up a mature glycan is accomplished in the Golgi.
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New insight into protein glycosylation in the development of Alzheimer’s disease
Cell Death Discovery, 2023 Alzheimer’s disease (AD) is a chronic neurodegenerative disease that seriously endangers the physical and mental health of patients, however, there are still no effective drugs or methods to cure this disease up to now.
Jingwei Zhao, Minglin Lang
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Getting Sugar Coating Right! The Role of the Golgi Trafficking Machinery in Glycosylation
Cells, 2021 The Golgi is the central organelle of the secretory pathway and it houses the majority of the glycosylation machinery, which includes glycosylation enzymes and sugar transporters. Correct compartmentalization of the glycosylation machinery is achieved by
Zinia D’Souza +3 more
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