Results 21 to 30 of about 238,453 (256)

Glycosylation of HDL-Associated Proteins and Its Implications in Cardiovascular Disease Diagnosis, Metabolism and Function

Frontiers in Cardiovascular Medicine, 2022
High-density lipoprotein (HDL) particles, long known for their critical role in the prevention of cardiovascular disease (CVD), were recently identified to carry a wide array of glycosylated proteins, and the importance of this glycosylation in the ...
Eduardo Z. Romo, Angela M. Zivkovic
doaj   +1 more source

Analysis of N-Glycosylation Sites in HIV glycoprotein 160 [PDF]

, 2011
HIV infection is a condition caused by the human immunodeficiency virus. The condition gradually destroys the immune system, which makes it harder for the body to fight infections. HIV presents a complex knot for scientists to unravel.
Rajendra Mandage
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Glycosylation and the global virome [PDF]

, 2022
The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features.
Cassandra, Pegg, Benjamin, Neely, Colin, Carlson, Gregory, Albery, Benjamin, Schulz   +4 more
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SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. [PDF]

, 2010
N-linked glycosylation is the most frequent modification of secreted and membrane-bound proteins in eukaryotic cells, disruption of which is the basis of the congenital disorders of glycosylation (CDGs).
Hudson H. Freeze, Silhavy, J.L., Christian R.H. Raetz, Al-Gazali, Lihadh, Swistun, Dominika, Dusica Babovic-Vuksanovic, Guan, Z., Blümel, Peter, Sykut-Cegielska, J., Hans van Bokhoven, Bokhoven, J.H.L.M. van, Ludwig Lehle, Lehle, Ludwig, Wevers, R.A., Al-Gazali, L., Houliston, S., Dobyns, W.B., Bassam R. Ali, Lefeber, D.J., Ali, Bassam R., Raetz, Christian R.H., Dirk J. Lefeber, Guan, Ziqiang, Ron A. Wevers, Hans Hombauer, Maciej Adamowicz, Jolanta Sykut-Cegielska, Stephanie L. Bielas, Ng, B.G., Freeze, H.H., Ewa Swiezewska, Wevers, Ron A., William B. Dobyns, Gleeson, Joseph G., Bobby G. Ng, Cantagrel, Vincent, Ng, Bobby G., Swiezewska, Ewa, Lefeber, Dirk J., De Brouwer, Arjan P., Houliston, Scott, Adamowicz, M., Silhavy, Jennifer L., Lihadh Al-Gazali, Ziqiang Guan, Éva Morava, Dobyns, William B., Adamowicz, Maciej, Morava, E., Babovic-Vuksanovic, Dusica, Raetz, C.R., Vincent Cantagrel, Lehle, L., Hombauer, H., Scott Houliston, Freeze, Hudson H., Jennifer L. Silhavy, Swistun, D., Blumel, P., Babovic-Vuksanovic, D., Cantagrel, V., Gleeson, J.G., Peter Blümel, Sykut-Cegielska, Jolanta, Arjan P. De Brouwer, Morava, Éva, Joseph G. Gleeson, Brouwer, A.P.M. de, van Bokhoven, Hans, Swiezewska, E., Hombauer, Hans, Dominika Swistun, Bielas, S.L., Ali, B.R., Bielas, Stephanie L.   +74 more
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Abnormal sialylation and fucosylation of saliva glycoproteins: Characteristics of lung cancer-specific biomarkers

Current Research in Pharmacology and Drug Discovery, 2022
Dysregulated surface glycoproteins play an important role in tumor cell proliferation and progression. Abnormal glycosylation of these glycoproteins may activate tumor signal transduction and lead to tumor development.
Ziyuan Gao, Mingming Xu, Shuang Yue, Huang Shan, Jun Xia, Junhong Jiang, Shuang Yang   +6 more
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Impact of Yeast Glycosylation Pathway on Cell Integrity and Morphology, Glycosylation, Stefana Petrescu (Ed.), ISBN: 978-953-51-0771-2, InTech, Available from: http://www.intechopen.com/books/glycosylation/impact-of-yeast-glycosylation-pathway-on-cell-integrity-and-morphology [PDF]

, 2012
Protein glycosylation is a multi step reaction, well conserved in the eukaryotic cells. In N-glycosylation reactions dolichyl phosphate (DolP) serves as a lipid acceptor of sugar residues forming DolPPGlcNAc2Man9Glc3.
Palamarczyk, Grazyna, Juchimiuk, Mateusz, Pasikowska, Monika, Janik, Anna, Orłowski, Jacek, Kruszewska, Joanna S.   +5 more
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Sugar activation and glycosylation in Plasmodium [PDF]

, 2015
TKS thanks previous funding from the Wellcome Trust (093228), SUSLA and BBSRC, and current funding from MRC (MR/M020118/1) and European Community’s Seventh Framework Programme under grant agreement No. 602773 (Project KINDRED). MC, JAR and LI are members
Smith, Terry K., Smith, Terry K, Izquierdo Lázaro, Luis, João A. Rodrigues, Rodrigues, João A., Cova, Marta, Marta Cova, Terry K. Smith, Izquierdo, Luis, Luis Izquierdo, Smith, Terry K; id_orcid   +10 more
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LINC00173 promotes Wilms’ tumor progression through MGAT1-mediated MUC3A N-glycosylation

, 2022
Recent studies have unveiled that LINC00173 promotes small cell lung cancer progression. However, LINC00173 has not been studied in Wilms’ tumor (WT).
Qingliang Zhu (12484975), Deming Zhan (12484978), Haoliang Xue (6033464), Yongguo Yang (11021152), Yankun Chong (12484981), Peng Zhu (277243)   +5 more
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DataSheet_1_PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy.docx

, 2022
Immune checkpoint therapy (ICT) with a monoclonal antibody (MAb) against programmed cell death protein 1 (PD-1) is a powerful clinical treatment for tumors.
Dan Lu (135836), Xiaopeng Ma (7843616), Dongli Ma (636809), Zepeng Xu (12176441), Min Jiang (56794), Kefang Liu (7024136), Ding Zhang (179432), George F. Gao (30860), Juanhua He (12176444), Shuguang Tan (4708243), Yan Chai (4708252)   +10 more
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A Chemoenzymatic Strategy toward Understanding O-GlcNAc Glycosylation in the Brain [PDF]

, 2007
Posttranslational modification to proteins represents a fundamental mechanism by which protein function is extended and elaborated. In the brain, modifications such as phosphorylation play critical roles in mediating neuronal communication and ...
Khidekel, Nelly
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