Results 11 to 20 of about 255,241 (301)
Glycosylation and behavioral symptoms in neurological disorders
Translational Psychiatry, 2023 Glycosylation, the addition of glycans or carbohydrates to proteins, lipids, or other glycans, is a complex post-translational modification that plays a crucial role in cellular function.
Prajitha Pradeep +2 more
doaj +2 more sources
Glycosylation of viral proteins: Implication in virus–host interaction and virulence
Virulence, 2022 Glycans are among the most important cell molecular components. However, given their structural diversity, their functions have not been fully explored. Glycosylation is a vital post-translational modification for various proteins.
Tingting Feng +6 more
doaj +2 more sources
Glycosylation in health and disease
Nature Reviews Nephrology, 2019 The glycome describes the complete repertoire of glycoconjugates composed of carbohydrate chains, or glycans, that are covalently linked to lipid or protein molecules.
Colin Reily +2 more
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Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading?
Cancer Cell, 2019 This review provides insights on the impact of glycosylation in cancer biology and its influence in the current approaches of targeted cancer therapies in the clinical setting.
Stefan Mereiter +2 more
exaly +2 more sources
Glycosylation in cancer: mechanisms and clinical implications
Nature Reviews Cancer, 2015 Salome S Pinho, Celso A Reis
exaly +2 more sources
Glycosylation as a dynamic regulator of RLR and cGAS-STING innate immune signalling pathways [PDF]
Communications BiologyInnate immune sensing by RIG-I-like receptors (RLRs) and the cGAS-STING pathway is tightly regulated by glycosylation. This review summarizes how distinct glycosylation modalities shape antiviral signaling at multiple levels.
Jie Tong +3 more
doaj +2 more sources
Current Biology, 2019 Eichler introduces the diversity of protein glycosylations and the roles of these modifications in regulating protein function.
J. Eichler
semanticscholar +3 more sources
Vertebrate protein glycosylation: diversity, synthesis and function
Nature Reviews Molecular Cell Biology, 2012 Kelley W Moremen +2 more
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O-GlcNAcylation of RIPK1 rescues red blood cells from necroptosis
Frontiers in Immunology, 2023 Necroptosis is a type of cell death with excessive inflammation and organ damage in various human diseases. Although abnormal necroptosis is common in patients with neurodegenerative, cardiovascular, and infectious diseases, the mechanisms by which O ...
Junghwa Seo +16 more
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Role of Sialyl-O-Acetyltransferase CASD1 on GD2 Ganglioside O-Acetylation in Breast Cancer Cells
Cells, 2021 The O-acetylated form of GD2, almost exclusively expressed in cancerous tissues, is considered to be a promising therapeutic target for neuroectoderm-derived tumors, especially for breast cancer.
Sumeyye Cavdarli +8 more
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