A genome-wide association study reveals specific transferases as candidate loci for bovine milk oligosaccharides synthesis. [PDF]
, 2019 BackgroundHuman milk oligosaccharides (OS) play a key role in brain and gut microbiota development of the neonate, but the underlying biosynthetic steps of OS in the mammary gland are still largely unknown.
Barile, Daniela +4 more
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Segmentally Variable Genes: A New Perspective on Adaptation [PDF]
, 2004 Genomic sequence variation is the hallmark of life and is key to understanding diversity and adaptation among the numerous microorganisms on earth. Analysis of the sequenced microbial genomes suggests that genes are evolving at many different rates.
Kasif, Simon +2 more
core +4 more sources
Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication
Chemistry – A European Journal, EarlyView.This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin +3 more
wiley +1 more source
Progress on Synthetic Biology for Steviol Glycosides Biosynthesis
Shipin gongye ke-jiStevioside, also known as stevia, is a class of diterpenoids extracted from stevia with high sweetness, low calories, safety and non-toxicity, hypoglycemic, hypotensive, and other physiological characteristics.
Mengyu LIU +7 more
doaj +1 more source
Open Biology, 2021 The dystroglycan (DG) complex plays a pivotal role for the stabilization of muscles in Metazoa. It is formed by two subunits, extracellular α-DG and transmembrane β-DG, originating from a unique precursor via a complex post-translational maturation ...
Maria Giulia Bigotti, Andrea Brancaccio
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Exploration, EarlyView.ABSTRACT Glioblastoma (GBM) is the most aggressive type of primary brain tumor, and its invasive properties contribute significantly to incomplete surgical resection and tumor recurrence. Despite extensive clinical efforts to mitigate GBM invasion, targeted therapies against GBM stem cells (GSCs), which drive invasion, remain incompletely understood ...
Rui Niu +3 more
wiley +1 more source
Chemical and Biocatalytic Routes to Arbutin †
Molecules, 2019 Arbutin (also called β-arbutin) is a natural product occurring in the leaves of a variety of different plants, the bearberries of the Ericaceae and Saxifragaceae families being prominent examples.
Hangyu Zhou +3 more
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Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes. [PDF]
, 1988 We have used mouse mAbs, 3F11 and 06B4, that are specific for highly conserved epitopes of Neisseria gonorrhoeae lipooligosaccharides (LOS) to identify immunochemically similar structures on human erythrocytes. mAb 3F11 agglutinated erythrocytes from all
Griffiss, J, Macher, B, Mandrell, R
core
Targeting UDP-Glycosyltransferase, Glucosamine-6-Phosphate Synthase and Chitin Synthase by Using Bioactive 1,8 Cineole for “Aspergillosis” Fungal Disease Mutilating COVID-19 Patients: Insights from Molecular Docking, Pharmacokinetics and In-vitro Studies [PDF]
, 2022 Arun Dev Sharma, Inderjeet Kaur
openalex +1 more source
Processivity in Bacterial Glycosyltransferases [PDF]
ACS Chemical Biology, 2019 Extracellular polysaccharides and glycoproteins of pathogenic bacteria assist in adherence, autoaggregation, biofilm formation, and host immune system evasion. As a result, considerable research in the field of glycobiology is dedicated to study the composition and function of glycans associated with virulence, as well as the enzymes involved in their ...
Liubov Yakovlieva, Marthe T. C. Walvoort
openaire +3 more sources