Results 71 to 80 of about 44,908 (222)
Frontiers in Physiology, 2017 Driven by interactions between lipids and proteins, biological membranes display lateral heterogeneity that manifests itself in a mosaic of liquid-ordered (Lo) or raft, and liquid-disordered (Ld) or non-raft domains with a wide range of different ...
Sami Rissanen +13 more
doaj +1 more source
Advanced Science, 2021 Several signaling processes in the plasma membrane are intensified by ceramides that are formed by sphingomyelinase‐mediated hydrolysis of sphingomyelin.
Hyun‐Ro Lee, Siyoung Q. Choi
doaj +1 more source
Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients
Journal of Pharmacy and Pharmacology, 2015 Abstract Objectives GM1-gangliosidosis is an inherited disorder characterized by the accumulation of GM1-gangliosides in many tissues and organs, particularly in the brain. Currently, there is no treatment available for patients with ganglioside storage diseases. Therefore, we investigated the effects
Yuki, Maeda +13 more
openaire +2 more sources
Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Non-radial Oscillation Modes of Compact Stars with a Crust [PDF]
, 2017 Oscillation modes of isolated compact stars can, in principle, be a fingerprint of the equation of state (EoS) of dense matter. We study the non-radial high-frequency l=2 spheroidal modes of neutron stars and strange quark stars, adopting a two-component
Flores, C. Vasquez +2 more
core +3 more sources
DADA Enhances CD8+ T Cell Stemness to Improve Anti‐Tumor Immunity and Immunotherapy Efficacy
Advanced Science, Volume 13, Issue 26, 8 May 2026.Diisopropylamine dichloroacetate (DADA) enhances CD8+ T cell stemness by improving OXPHOS and mitochondrial fitness in a PDK1‐depenpendent manner. This metabolic shift strengthens CD8+ T cell anti‐tumor immunity, improves responses to PD‐1 blockade, and endows CAR‐T cells with prolonged persistence and resistance to terminal exhaustion, highlighting a ...
Mingyue Bi +12 more
wiley +1 more source
The Role of Lipid Environment in Ganglioside GM1-Induced Amyloid β Aggregation
Membranes, 2020 Ganglioside GM1 is the most common brain ganglioside enriched in plasma membrane regions known as lipid rafts or membrane microdomains. GM1 participates in many modulatory and communication functions associated with the development, differentiation, and ...
Vladimir Rudajev, Jiri Novotny
doaj +1 more source
Brain and Behavior, Volume 16, Issue 5, May 2026.Chronic inflammatory demyelinating polyneuropathy is an autoimmune disorder causing demyelination, leading to distal weakness, sensory loss, and autonomic dysfunction. Immune activation triggers macrophage‐mediated myelin damage and conduction failure.
Ayesha Khan +11 more
wiley +1 more source
Stem Cell ResearchGM1 gangliosidosis (GM1) is a rare autosomal recessive neurogenerative lysosomal storage disease characterized by deficiency of beta-galactosidase (β-gal) and intralysosomal accumulation of GM1 ganglioside and other glycoconjugates.
Allisandra K. Rha +5 more
doaj +1 more source
A CMOS Q-Enhancement Bandpass-Filter For Use In Paging Receivers [PDF]
, 1998 Paging receivers often have to work in a dense\ud signal environment. This poses high demands on the preselection\ud filter. One of the most difficult aspects is the large\ud image rejection demand, which only can be satisfied by use\ud of a narrow-band ...
Eikenbroek, J.W.Th. +3 more
core +2 more sources