Results 51 to 60 of about 44,908 (222)

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Antikaon condensation in neutron stars

, 2000
We investigate the condensation of charged $K^-$ meson and neutral $\bar K^0$ meson in dense neutron star matter. Calculations are performed in relativistic mean field models in which both the baryon-baryon and (anti)kaon-baryon interactions are mediated
Bandyopadhyay, Debades, Greiner, Walter, International School for Advanced Studies, Trieste (Italy), Pal, Subrata   +3 more
core   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source

Ganglioside-monosialic acid (GM1) for prevention of chemotherapy-induced peripheral neuropathy: a meta-analysis with trial sequential analysis

BMC Cancer, 2021
Background Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect that largely remains an unresolved clinical issue, leading to long-term morbidity.
Shaoyong Wu, Xiaohui Bai, Caixia Guo, Zhimei Huang, Handong Ouyang, Jingxiu Huang, Weian Zeng   +6 more
doaj   +1 more source

The Ganglioside Monosialotetrahexosylganglioside Protects Auditory Hair Cells Against Neomycin-Induced Cytotoxicity Through Mitochondrial Antioxidation: An in vitro Study

Frontiers in Cellular Neuroscience, 2021
Neomycin is a common ototoxic aminoglycoside antibiotic that causes sensory hearing disorders worldwide, and monosialotetrahexosylganglioside (GM1) is reported to have antioxidant effects that protect various cells.
Yujin Li, Yujin Li, Ao Li, Ao Li, Ao Li, Chao Wang, Xin Jin, Yaoting Zhang, Ling Lu, Ling Lu, Ling Lu, Shou-Lin Wang, Xia Gao, Xia Gao, Xia Gao   +14 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Raft microdomain localized in the luminal leaflet of inner membrane complex of living Toxoplasma gondii

European Journal of Cell Biology, 2021
Membrane microdomains or rafts, sterol- and sphingolipid-rich microdomains in the plasma membrane have been studied extensively in mammalian cells. Recently, rafts were found to mediate virulence in a variety of parasites, including Toxoplasma gondii ...
Rikako Konishi, Yuna Kurokawa, Kanna Tomioku, Tatsunori Masatani, Xuenan Xuan, Akikazu Fujita   +5 more
doaj   +1 more source

Very wide range tunable CMOS/bipolar current mirrors with voltage clamped input [PDF]

, 1999
In low power current mode signal processing circuits it is often necessary to use current mirrors to replicate and amplify/attenuate current signals and clamp the voltage of nodes with high parasitic capacitances so that the smallest currents do not ...
Andreou, Andreas G., Linares Barranco, Bernabé, Serrano Gotarredona, María Teresa   +2 more
core   +1 more source

Supercritical Angle Fluorescence and Raman Techniques in Biophotonics

Laser &Photonics Reviews, EarlyView.
Supercritical angle fluorescence (SAF) microscopy and supercritical angle Raman (SAR) spectroscopy have emerged as powerful tools in the field of biophotonics, enabling high‐resolution imaging and spectroscopy of biological specimens near interfaces. This review article provides a comprehensive overview of the principles, techniques, applications, and ...
Subir Das, Nathalia Simea Münch, Stefan Seeger   +2 more
wiley   +1 more source

Physics input for modelling superfluid neutron stars with hyperon cores

, 2014
Observations of massive ($M \approx 2.0~M_\odot$) neutron stars (NSs), PSRs J1614-2230 and J0348+0432, rule out most of the models of nucleon-hyperon matter employed in NS simulations.
Gusakov, M. E., Haensel, P., Kantor, E. M.   +2 more
core   +1 more source