Results 41 to 50 of about 44,908 (222)

GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson\u27s Disease. [PDF]

, 2019
While GM1 may interact with α-synuclein in vitro to inhibit aggregation, the ability of GM1 to protect against α-synuclein toxicity in vivo has not been investigated.
Aras, Radha, Brotchie, Jonathan M., Koprich, James B., Schneider, Jay S., Singh, Vikrant, Williams, Courtney K.   +5 more
core   +1 more source

CTBPro: A Next‐Generation Cholera Toxin Subunit B‐Based Neuroanatomical Tracer With Superior Brightness, Stability, and Sensitivity for Enhanced Neural Circuit Mapping

Advanced Science, EarlyView.
CTBPro is a next‐generation cholera toxin B–based tracer engineered by fusing CTB to the ultra‐stable fluorescent protein mBaojin. Exhibiting markedly enhanced molar brightness, CTBPro enables high‐fidelity neuronal labeling across multiple administration routes.
Xinghua Quan, Yude Lou, Huiqi Xie, Yifei Wang, Yanzhe Zhang, Yiran Ge, Linhe Yang, Xiaoxuan Zhang, Qingmiao Zhou, Huaizong Shen, Longxing Cao, Xin Jin, Jie‐Min Jia   +12 more
wiley   +1 more source

A simple, nonenzymatic method for desialylating polysialylated ganglio-N-tetraose series gangliosides to produce GM1

Journal of Lipid Research, 1999
Dowex-50W-H+ was used to catalyze the highly selective desialylation of polysialylated ganglio-N-tetraose series gangliosides to yield primarily GM1. High performance thin-layer chromatographic analysis of recovered lipid indicated that 60–70% of the ...
Cara-Lynne Schengrund, Pavol Kováč
doaj   +1 more source

Transition of $\rho \rightarrow \pi \gamma$ in Lattice QCD

, 2015
With the ongoing experimental interest in exploring the excited hadron spectrum, evaluations of the matrix elements describing the formation and decay of such states via radiative processes provide us with an important connection between theory and ...
Kamleh, Waseem, Leinweber, Derek B., Mahbub, M. Selim, Menadue, Benjamin J., Owen, Benjamin J.   +4 more
core   +1 more source

Electromagnetic properties of the Delta(1232) and decuplet baryons in the self-consistent SU(3) chiral quark-soliton model [PDF]

, 2008
We examine the electromagnetic properties of the Delta(1232) resonance within the self-consistent chiral quark-soliton model. In particular we present the Delta form factors of the vector-current GE0, GE2 and GM1 for a momentum-transfer range of $Q^{2 ...
A. Blotz, A. J. Buchmann, Antonio Silva, K. Goeke, Marc Vanderhaeghen, R. G. Edwards, Tim Ledwig, V. de Alfaro   +7 more
core   +2 more sources

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Cholesterol accelerates the binding of Alzheimer’s beta-amyloid peptide to ganglioside GM1 through a universal hydrogen-bond-dependent sterol tuning of glycolipid conformation.

Frontiers in Physiology, 2013
Age-related alterations of membrane lipids in brain cell membranes together with high blood cholesterol are considered as major risk factors for Alzheimer’s disease. Yet the molecular mechanisms by which these factors increase Alzheimer’s risk are mostly
Jacques eFantini, Nouara eYahi, Nicolas eGarmy   +2 more
doaj   +1 more source

Vesicular Ganglioside GM1 From Breast Tumor Cells Stimulated Epithelial-to-Mesenchymal Transition of Recipient MCF-10A Cells

Frontiers in Oncology, 2022
Small extracellular vesicles (sEVs) are a type of membrane structure secreted by cells, which are involved in physiological and pathological processes by participating in intercellular communication.
Qilong Ma, Dinghao Zhuo, Feng Guan, Xiang Li, Xiaomin Yang, Xiaomin Yang, Zengqi Tan   +6 more
doaj   +1 more source

Human Agency Drivers for Eco‐Innovation: The Role of Environmental Entrepreneurship Orientation and Green Human Resource Management

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines how human agency drives eco‐innovation by analyzing the mediating role of green human resource management (HRM) in the relationship between environmental entrepreneurship orientation (EEO) and eco‐innovation. By integrating resource orchestration theory with the Ability–Motivation–Opportunity (AMO) framework, the study ...
Ana Labella‐Fernández, Diego A. Vazquez‐Brust, Javier Martínez‐del‐Río, Rui Yang   +3 more
wiley   +1 more source

A relativistic quark model for the Omega- electromagnetic form factors

, 2009
We compute the Omega- electromagnetic form factors and the decuplet baryon magnetic moments using a quark model application of the Covariant Spectator Theory.
Franz Gross, G. Ramalho, G. Ramalho, Greiner Muller, K. Tsushima, M. I. Krivoruchenko, M. I. Krivoruchenko, S. Sahu, S. S. Gershtein, S. S. Gershtein, V. Drach   +10 more
core   +1 more source