High-throughput imaging method for direct assessment of GM1 ganglioside levels in mammalian cells
Data in Brief, 2016 GM1-gangliosidosis is an inherited autosomal recessive disorder caused by mutations in the gene GLB1, which encodes acid β-galactosidase (β-gal). The lack of activity in this lysosomal enzyme leads to accumulation of GM1 gangliosides (GM1) in cells.
Walter Acosta +3 more
doaj +1 more source
Anti-Inflammatory Effects of GM1 Ganglioside on Endotoxin-Induced Uveitis in Rats
Biomolecules, 2022 Exogenous ganglioside GM1 has been reported to exert an immunomodulatory effect. We investigated the anti-inflammatory effect of GM1 ganglioside on endotoxin-induced uveitis (EIU) in rats and RAW 264.7 macrophages.
Tzu-Heng Weng +2 more
doaj +1 more source
Molecules, 2014 A new ganglioside transformed strain isolated from soil was identified as Cellulosimicrobium sp. 21. It produced a sialidase which transformed polysialo-gangliosides GD1 and GT1 into a monosialoterahexosylganglioside, i.e., ganglioside GM1. The sialidase
Yan Zheng +7 more
doaj +1 more source
Ceramide structure dictates glycosphingolipid nanodomain assembly and function
Nature Communications, 2021 Gangliosides such as GM1 present in the outer leaflet of the plasma membrane of eukaryotic cells are essential for many cellular functions and pathogenic interactions.
Senthil Arumugam +10 more
doaj +1 more source
Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells [PDF]
BMB Reports, 2012 Gangliosides play important roles in the control of severalbiological processes, including proliferation and transmembranesignaling. In this study, we demonstrate the effect ofganglioside GM1 on the proliferation of mouse inducedpluripotent stem cells ...
Young-Kug Choo
doaj
Color Superconductivity in Compact Stars and Gamma Ray Bursts [PDF]
, 2003 We study the effects of color superconductivity on the structure and formation of compact stars. We show that it is possible to satisfy most of recent observational boundaries on masses and radii if a diquark condensate forms in a hybrid or a quark star.
Drago, A., Lavagno, A., Pagliara, G.
core +3 more sources
Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance [PDF]
, 2016 Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus of glycoprotein and glycolipid acceptors.
Aja, Susan +7 more
core +1 more source
Pathophysiology of Ganglioside GM1 in Ischemic Stroke: Ganglioside GM1: A Critical Review [PDF]
Cell Transplantation, 2019 Ganglioside GM1 is a member of the ganglioside family which has been used in many countries and is thought of as a promising alternative treatment for preventing several neurological diseases, including cerebral ischemic injury. The therapeutic effects of GM1 have been proved both in neonates and in adults following ischemic brain damage; however, its
Zhang, Wenchao +5 more
openaire +4 more sources
A study of the N to Delta transition form factors in full QCD
, 2005 The N to Delta transition form factors GM1, GE2 and GC2 are evaluated using dynamical MILC configurations and valence domain wall fermions at three values of quark mass corresponding to pion mass 606 MeV, 502 MeV and 364 MeV on lattices of spatial size ...
Alexandrou, Constantia +7 more
core +1 more source
Complex of GM1- and GD1a-like lipo-oligosaccharide mimics GM1b, inducing anti-GM1b antibodies. [PDF]
PLoS ONE, 2015 Molecular mimicry between Campylobacter jejuni lipo-oligosaccharides (LOSs) and human gangliosides GM1 and GD1a induces the production of anti-GM1 and anti-GD1a antibodies, and the development of Guillain-Barré syndrome.
Michiaki Koga +3 more
doaj +1 more source