Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi +6 more
wiley +1 more source
Protocol to identify the signaling network of nucleotide second messengers in Shigella sonnei. [PDF]
Cui B, Chen X, Wang M, Deng Y.
europepmc +1 more source
The use of edible insects in human food
Abstract The world population is expected to reach approximately 10 billion people by 2050, which will significantly increase global food demand and may lead to agricultural shortages and a higher risk of food insecurity. In this context, this review discusses the potential of insects as alternative sources of animal protein, addressing their ...
Pamela Barroso de Oliveira +5 more
wiley +1 more source
Personalized, digitally designed 3D-Printed protein substitutes: Advancing medical food for PKU patients. [PDF]
Marcello F +5 more
europepmc +1 more source
Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia +3 more
wiley +1 more source
Impact of facility based versus home based growth monitoring and promotion programs on child nutritional status in rural Bangladesh. [PDF]
Hossain M +6 more
europepmc +1 more source
Early Autonomic Burden in Prodromal Parkinson's Disease Predicts Cognitive Impairment
Abstract Background Autonomic dysfunction is a known contributor to cognitive impairment in Parkinson's disease (PD), but its impact during prodromal stage is unknown. Objective The aim was to determine whether early autonomic burden predicts incident cognitive impairment in prodromal PD.
A. Enrique Martinez‐Nunez +5 more
wiley +1 more source
Multi-omic profiling and preclinical efficacy of fratricide-driven, unedited CD7 CAR-T cells in T-cell leukemia. [PDF]
Freile JÁ +18 more
europepmc +1 more source
Perspective: Depression in Persons with Parkinson's Disease
Abstract Depression is a prevalent and disabling syndrome characterized by sustained sadness and/or anhedonia, as well as cognitive and physical symptoms. In Parkinson's disease (PD), depression is both common and clinically challenging due to overlapping symptoms and complex etiologic interactions. Major depressive disorder occurs in approximately 17%
Albert F.G. Leentjens +1 more
wiley +1 more source
Regulatory, ethical, and clinical barriers to exosome use in interventional pain medicine. [PDF]
Bourcier AJ, Kirkor ZM.
europepmc +1 more source

