Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Dubey, Badri N. +6 more
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Aid conditionalities, international Good Manufacturing Practice standards and local production rights: a case study of local production in Nepal [PDF]
© 2015 Brhlikova et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium ...
A Abdo-Rabbo +47 more
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The application of Good Manufacturing Practice (GMP) can improve quality of products. Good manufacturing practice aim to make a safe product to be consumed. Attitude of food handlers can affect practice of food handlers on production process. The purpose
Maya Amelia, Annis Adi
doaj +1 more source
MicroRNAs affecting the susceptibility of melanoma cells to CD8+ T cell‐mediated cytolysis
Background The regulatory functions of microRNAs (miRNAs) in anti‐tumour immunity have been mainly described in immune effector cells. Since little is known about miRNA effects on the susceptibility of target cells during T cell—target cell interaction ...
Antonino A. Pane +8 more
doaj +1 more source
A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus [PDF]
Generally, the second messenger bis-(3’-5’)-cyclic dimeric GMP (c-di-GMP) regulates the switch between motile and sessile lifestyles in bacteria. Here, we show that c-di-GMP is an essential regulator of multicellular development in the social bacterium ...
A Duerig +87 more
core +3 more sources
Gaussian Message Passing for Overloaded Massive MIMO-NOMA
This paper considers a low-complexity Gaussian Message Passing (GMP) scheme for a coded massive Multiple-Input Multiple-Output (MIMO) systems with Non-Orthogonal Multiple Access (massive MIMO-NOMA), in which a base station with $N_s$ antennas serves $N_u$
Guan, Yong Liang +4 more
core +1 more source
Identification of the YfgF MASE1 domain as a modulator of bacterial responses to aspartate [PDF]
Complex 3'-5'-cyclic diguanylic acid (c-di-GMP) responsive regulatory networks that are modulated by the action of multiple diguanylate cyclases (DGC; GGDEF domain proteins) and phosphodiesterases (PDE; EAL domain proteins) have evolved in many bacteria.
Agasing, A. +3 more
core +1 more source
A Hybrid Model of Integrating Sentiment Analysis and Key Market Indicators for IPO Listing Trend Prediction [PDF]
Initial Public Offerings (IPOs) provide great opportunities for companies to grow and expand, and they allow investors to invest their money wisely to get a decent Return on Investment (ROI) in the short term.
Ashish Garg +2 more
doaj +1 more source
Bacterial rotary export ATPases are allosterically regulated by the nucleotide second messenger cyclic-di-GMP [PDF]
The widespread second messenger molecule cyclic di-GMP (cdG) regulates the transition from motile and virulent lifestyles to sessile, biofilm-forming ones in a wide range of bacteria. Many pathogenic and commensal bacterial-host interactions are known to
Abel +89 more
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Targeted cancer immunotherapy with irradiated, granulocyte–macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that to be
Markus D. Lacher +13 more
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