Results 31 to 40 of about 187,323 (286)

Aid conditionalities, international Good Manufacturing Practice standards and local production rights: a case study of local production in Nepal [PDF]

, 2015
© 2015 Brhlikova et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium ...
A Abdo-Rabbo, AH Meshkini, Allyson M. Pollock, B Shakya, B Shrestha, DA Grimes, DDA, E Toledo, ES Pinheiro, GAO, H Dixit, HSSP, I Harper, Ian Harper, J Abraham, J-M Guimier, K Losse, K Morimoto, K Timmermans, M Santhosh, Madhusudan Subedi, MHP, Nabin Rawal, P Brhlikova, P Trouiller, P Trouiller, PEPFAR, Petra Brhlikova, PG Mujinja, S Budhathoki, S Chaudhuri, S Hill, S Palaian, Samita Bhattarai, SAWTEE, Thapa, UNCTAD, UNIDO, W Kaplan, WA Kaplan, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO WHO   +47 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

GD2: hopes and challenges for the treatment of pediatric patients with tumors of the central nervous system

npj Precision Oncology
Pediatric Central Nervous System (CNS) tumors are the leading cause of cancer-related death in children, yet effective treatment options remain limited.
Alba Clara Fernández-Rilo, Emmanuel de Billy, Giada Del Baldo, Biagio De Angelis, Sabrina Rossi, Francesca Del Bufalo, Concetta Quintarelli, Franco Locatelli, Angela Mastronuzzi, Maria Vinci   +9 more
doaj   +1 more source

GOOD HYGIENE PRACTICES AS AN IMPORTANT PROGRAM FOR SAFETY OF FINAL PRODUCTS

Food and Environment Safety, 2021
In order to meet the requirements regarding food safety, in addition to the HACCP system, food operators are required to adopt, implement and document Good Hygiene Practice (GMP), Good Manufacturing Practice (GMP), Standard Operating Procedures (SOP) and
Ljubica TRAJKOSKA, Maja TRAJANOSKA, Biljana TRAJKOVSKA, Ljupche KOCHOSKI, Vesna KARAPETKOVA-HRISTOVA   +4 more
doaj  

Ca2+-dependent changes in cyclic GMP levels are not correlated with opening and closing of the light-dependent permeability of toad photoreceptors. [PDF]

, 1982
We have measured the levels of 3',5'-guanosine monophosphate (cyclic GMP) in isolated retinas from toad to investigate their correlation to the opening and closing of the light-dependent permeability of photoreceptors. When Ca2+-induced changes in cyclic
Fain, GL, Woodruff, ML
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

IMPLEMENTASI GMP BERDASAR PADA ISO/TS 22002-1 TERHADAP PRODUKSI IKAN TERI NASI (Stolepherus sp.) DI PT MARINAL INDOPRIMA

Agrointek, 2021
ISO / TS 22002-1 is an excellent document to use as a requirement program in the application of a food safety management system for any food producer or processor. This guideline can be applied at PT.
Sri Handayani, Lorine Tantalu, Rosalia May Nyonya   +2 more
doaj   +1 more source

Inner-gMP and gMP-inner inverses

Hacettepe Journal of Mathematics and Statistics
Solving some systems of operator equations, new kinds of generalized inverses are introduced. Since these new inverses can be expressed by inner and gMP inverses, they are called inner-gMP and gMP-inner inverses. In this way, the concepts of gMP, 1MP and MP1 inverses are generalized.
Dunja Stojanovic, Dijana Mosic
openaire   +2 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Simulation: A Powerful Tool for Training Professional Skills in Cleanrooms

Pharmaceutical Technology in Hospital Pharmacy, 2016
This study presents the conception of a simulator for training and evaluating workers that are going to enter and operate in a cleanroom. First, this article explains the pedagogical engineering process developed in order to conceive this pedagogical ...
Denami Maria
doaj   +1 more source