Results 41 to 50 of about 188,404 (288)

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Simulation: A Powerful Tool for Training Professional Skills in Cleanrooms

open access: yesPharmaceutical Technology in Hospital Pharmacy, 2016
This study presents the conception of a simulator for training and evaluating workers that are going to enter and operate in a cleanroom. First, this article explains the pedagogical engineering process developed in order to conceive this pedagogical ...
Denami Maria
doaj   +1 more source

IMPLEMENTASI ASPEK GMP, SSOP, DAN SISTEM HACCP PADA UMKM ONCOM DAWUAN

open access: yesAgrointek, 2021
Dawuan is a sub-district in Subang Regency, West Java, which is famous for its special food, Oncom. Oncom is one of the typical foods from Java which is a fermented product from the substrate of peanut meal or tofu pulp which has been inoculated with red
Rita Purwasih
doaj   +1 more source

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. [PDF]

open access: yes, 1985
We have previously characterized a monoclonal antibody, S12, that binds only to activated platelets (McEver, R.P., and M.N. Martin, 1984, J. Biol. Chem., 259:9799-9804). It identifies a platelet membrane protein of Mr 140,000, which we have designated as
Bainton, DF   +4 more
core   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan   +14 more
wiley   +1 more source

Pelatihan Good Manufacturing Practice (GMP) pada Usaha Pangan Binaan Universitas Andalas

open access: yesWarta Pengabdian Andalas, 2020
Food business is a very promising, but the products must be safe and worth buying. Good manufacturing practices (GMP) are production practices which considering various aspects, such as preventing food contamination during the production process, and ...
Tivany Edwin   +4 more
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Nanopharmaceutics: Part I—Clinical Trials Legislation and Good Manufacturing Practices (GMP) of Nanotherapeutics in the EU

open access: yesPharmaceutics, 2020
The latest advances in pharmaceutical technology are leading to the development of cutting edged approaches to produce what is now known as the “Holy Grail” of medicine—nanopharmaceutics.
Eliana B. Souto   +8 more
doaj   +1 more source

Improved Lower Bounds on Mutual Information Accounting for Nonlinear Signal-Noise Interaction [PDF]

open access: yes, 2018
In fiber-optic communications, evaluation of mutual information (MI) is still an open issue due to the unavailability of an exact and mathematically tractable channel model.
Agrell, Erik   +4 more
core   +2 more sources

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

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