Electrophysiological and morphological evidence for synchronized GnRH pulse generator activity among Kisspeptin/neurokinin B/dynorphin A (KNDy) neurons in goats. [PDF]
Neurons in the arcuate nucleus (ARC) that concomitantly express kisspeptin, neurokinin B (NKB) and dynorphin A are termed KNDy neurons and are likely candidates for the intrinsic gonadotropin-releasing hormone (GnRH) pulse generator.
Wakabayashi Y +4 more
europepmc +4 more sources
Progesterone-Mediated Inhibition of the GnRH Pulse Generator: Differential Sensitivity as a Function of Sleep Status. [PDF]
Kim SH +7 more
europepmc +3 more sources
Kisspeptin, neurokinin B, and dynorphin act in the arcuate nucleus to control activity of the GnRH pulse generator in ewes. [PDF]
Goodman RL +9 more
europepmc +3 more sources
Definition of the hypothalamic GnRH pulse generator in mice. [PDF]
Clarkson J +10 more
europepmc +4 more sources
OR09-02 Chemogenetic Manipulation Of Brainstem Noradrenergic Neurons Modulates The Activity Of The Kisspeptin GnRH Pulse Generator In Mice [PDF]
Disclosure: S. Vas: None. M. Ruiz-Cruz: None. S. Han: None. S. Hwa-Yeo: None. A.E. Herbison: None. The kisspeptin neurons in the arcuate nucleus (ARNKISS) represent the GnRH pulse generator that drives pulsatile luteinizing hormone secretion.
Szilvia Vas +4 more
europepmc +2 more sources
Characterization of GnRH Pulse Generator Activity in Male Mice Using GCaMP Fiber Photometry. [PDF]
Kisspeptin neurons located in the hypothalamic arcuate nucleus are thought to represent the GnRH pulse generator responsible for driving pulsatile LH secretion.
S. Han +3 more
semanticscholar +2 more sources
Electrophysiological approach to the hypothalamic GnRH pulse generator. [PDF]
The hypothalamic GnRH pulse generator that regulates intermittent GnRH discharge into the pituitary portal circulation and thereby modulates pulsatile secretion of LH has been recognized as a key determinant of the reproductive function in mammals. Thus,
Y. Mori, T. Tanaka
semanticscholar +2 more sources
The hypothalamic GnRH pulse generator: multiple regulatory mechanisms. [PDF]
Krsmanovic LZ +4 more
europepmc +3 more sources
GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice [PDF]
Kisspeptin neurons in the arcuate nucleus of the hypothalamus generate GnRH pulses, and act as critical initiators of functional gonadotrophin secretion, and reproductive competency.
G. Lass +9 more
semanticscholar +2 more sources
KNDy neurons as the GnRH pulse generator: Recent studies in ruminants. [PDF]
Nestor CC +4 more
europepmc +2 more sources

