Results 181 to 190 of about 214,335 (315)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Secretion of the HBV small surface antigen is driven by an ER autophagic pathway. [PDF]

Hepatol Commun
Cao H, Krueger E, Chen J, Yang H, Chia JJ, Beran RK, Tam J, Kornyeyev D, Holdorf MM, McNiven MA.   +9 more
europepmc   +1 more source

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

BMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao, Xiangwei Lv, Miaomiao Zhang, Jiayi Liu, Yun Chen, Yunna Li, Gaoyuan Liu, Fuming Yang, Ziqiang Han, Yunyun Wei   +9 more
wiley   +1 more source

Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway. [PDF]

PLoS Pathog
Caddell TM, Mulloy RP, Corcoran JA, Pringle ES, McCormick C.   +4 more
europepmc   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Reversible Holmes Tremor due to Middle Cerebral Artery Giant Aneurysm

Tremor and Other Hyperkinetic Movements, 2019
Tino Emanuele Poloni, Alberto Galli, Arenn Faye Carlos, Emanuela Riva, Valentina Medici, Annalisa Davin, Antonio Guaita, Mauro Ceroni   +7 more
doaj   +1 more source

ATP7A-fibulin-4 complex delivers copper in the Golgi to activate LOX in renal fibrosis. [PDF]

JCI Insight
Zhou W, Zheng Y, Liu Y, Liu J, Liu Y, Niu Y, Yu Y, Zhang X, Zhang Y, Yu C.   +9 more
europepmc   +1 more source

trans-Golgi retention of a plasma membrane protein : mutations in the cytoplasmic domain of the asialoglycoprotein receptor subunit h1 result in trans-Golgi retention [PDF]

, 1995
J M Wahlberg, M Spiess, F Reymond, Wahlberg, J. M., Simmen, T., Spiess, M., I Geffen, Reymond, F., T Simmen, Geffen, I.   +9 more
core   +1 more source

β‐1,4‐galactosyltransferase 1 inhibitors modulate cellular N‐glycan profiles

Biotechnology Progress, EarlyView.
Graphical representation of the study workflow used to investigate the effects of known in vitro galactosyltransferase inhibitors on cell culture performance and recombinant IgG galactosylation. Abstract N‐glycosylation is a key post‐translational modification of proteins influencing their physicochemical properties as well as biological activity. This
Jaka Kranjc, Stane Pajk, Marko Anderluh, Anja Pišlar, Matjaž Brinc   +4 more
wiley   +1 more source

Correction: Conventional and neuropsychological criteria for mild cognitive impairment show similar prognostic value for dementia across 12 years in a non-clinical setting

Scientific Reports
Simone Galati, Michele Rossi, Federica Del Signore, Giulia Locatelli, Antonio Guaita, Elena Rolandi   +5 more
doaj   +1 more source