Results 191 to 200 of about 214,335 (315)

ER-Golgi dysfunction and vesicular transport alterations in rheumatoid arthritis immune cells. [PDF]

Front Immunol
Shi Y, Zhang W, Li C, Liu F, Yin L, Liu D, Hong X, Zeng Z, Li H, Dai Y, Tang D, Gong W.   +11 more
europepmc   +1 more source

Enzymatic Prenylation of Proteins and Peptides: From Cysteine S‐Prenylation to Tryptophan‐Selective Biocatalysis

Chemistry – A European Journal, EarlyView.
This review highlights biocatalytic prenylation as a versatile strategy for tailoring the functional properties of peptides and proteins. By comparing branched isoprenoids with linear lipids, we illustrate how specific prenyl architectures modulate the behaviors of lipidated proteins within membrane environments.
Daisuke Fujinami, Hikari Ozawa, Sohei Ito   +2 more
wiley   +1 more source

Built different: ER cisternae formed by the Arabidopsis Lunapark proteins differ in ultrastructure and affect ER-Golgi transport. [PDF]

New Phytol
Pain C, Spatola Rossi T, Field N, Mata C, Candeo A, Ali MW, Moreira-Leite F, Botchway SW, Brandizzi F, Kriechbaumer V.   +9 more
europepmc   +1 more source

Organelle‐Resolved Tetrazine‐trans‐Cyclooctene Click Chemistry for Cargo Delivery and Release

Chemistry – A European Journal, EarlyView.
Bioorthogonal click chemistry tools provide a means for specific intracellular conjugation of molecules. In this study, we used reactive tetrazine (Tz) and TCO moieties for labeling of organelles and organelle‐specific delivery and activation of doxorubicin prodrugs.
Oleh Durydivka, Marek Chovanec, Rastislav Dzijak, Michal Rahm, Jachym Hrusak, Paul E. Reyes‐Gutierrez, Milan Vrabel   +6 more
wiley   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

Stress-induced proteome remodeling at the Golgi-endosome interface. [PDF]

J Cell Sci
Simon G, Pol SA, Dendusic M, Schulze N, Stupia S, Koci M, Buzuk L, Thier B, Steinbach P, Trinh H, Schillinger J, Ninck S, Kaschani F, Kaiser M, Ehrmann M, Paschen A, Hellerschmied D.   +16 more
europepmc   +1 more source

Making Two out of One: Kinesin Motors Driving Plant Cell Division

Cytoskeleton, EarlyView.
ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley   +1 more source

TMEM87A suppresses ferroptosis and increases cancer immunotherapy resistance by maintaining the Golgi apparatus pH homeostasis. [PDF]

Nat Cancer
Li J, Zhou Y, Li X, Yin S, Gao Y, Shang H, Lai Y, Yang L, Xue Y, Li X, Li Y, Chang Z, Chen J, Cheng X, Zhang X, Chu Q, Lu F, Wang W.   +17 more
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

LRRK2 regulates ArfGAP1 membrane localization, activity and neuronal integrity via phosphorylation within its lipid-sensing ALPS2 motif. [PDF]

Front Mol Neurosci
Islam MS, Cóppola-Segovia V, Musso A, Moore DJ.   +3 more
europepmc   +1 more source