Angewandte Chemie - International Edition, 2021 Golgi apparatus is emerging as a key signaling hub of cells and an important target for cancer therapy, but there are few approaches for targeting Golgi and selectively killing cancer cells.
Jiaqing Wang, Hongjian He, Meihui Yi
exaly +2 more sources
Adaptation of the Golgi Apparatus in Cancer Cell Invasion and Metastasis
Frontiers in Cell and Developmental Biology, 2021 The Golgi apparatus plays a central role in normal cell physiology by promoting cell survival, facilitating proliferation, and enabling cell-cell communication and migration.
Sarah Bui +5 more
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Ubiquitin-mediated degradation at the Golgi apparatus [PDF]
Frontiers in Molecular Biosciences, 2023 The Golgi apparatus is an essential organelle of the secretory pathway in eukaryotic cells. It processes secretory and transmembrane proteins and orchestrates their transport to other endomembrane compartments or the plasma membrane.
Lana Buzuk, Doris Hellerschmied
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The Preparation of Golgi Apparatus-Targeted Polymer Dots Encapsulated with Carbon Nanodots of Bright Near-Infrared Fluorescence for Long-Term Bioimaging [PDF]
Molecules, 2023 As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with targeted fluorescence imaging technology is of enormous importance
Yiping Lu +9 more
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The Golgi apparatus in neurorestoration [PDF]
Journal of Neurorestoratology, 2019 The central role of the Golgi apparatus in critical cellular processes such as the transport, processing, and sorting of proteins and lipids has placed it at the forefront of cell science.
Jianyang Liu +5 more
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The endoplasmic reticulum-resident chaperone heat shock protein 47 protects the Golgi apparatus from the effects of O-glycosylation inhibition. [PDF]
PLoS ONE, 2013 The Golgi apparatus is important for the transport of secretory cargo. Glycosylation is a major post-translational event. Recognition of O-glycans on proteins is necessary for glycoprotein trafficking.
Shingo Miyata +4 more
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The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes [PDF]
Scientific ReportsWhite adipocytes are a major component of white adipose tissue (WAT) and help to maintain systemic metabolic homeostasis by storing energy and secreting adipokines. In mice deficient in the protein WWP1 (WW domain-containing E3 ubiquitin protein ligase 1)
Yuka Nozaki +8 more
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The centrosome–Golgi apparatus nexus [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2014 A shared feature among all microtubule (MT)-dependent processes is the requirement for MTs to be organized in arrays of defined geometry. At a fundamental level, this is achieved by precisely controlling the timing and localization of the nucleation events that give rise to new MTs. To this end, MT nucleation is restricted to specific subcellular sites
R. Rios
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Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver
Journal of Lipid Research, 1969 It has been proposed that particles within tubules and vesicles of the Golgi apparatus of liver cells are precursors of very low density lipoproteins in blood plasma. To characterize these particles we isolated a cell fraction rich in Golgi apparatus and
Robert W. Mahley +2 more
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Characterization of the glutathione redox state in the Golgi apparatus [PDF]
Redox BiologyRedox homeostasis is crucial for cell function, and, in eukaryotic cells, studying it in a compartmentalized way is essential due to the redox variations between different organelles.
Carla Miró-Vinyals +5 more
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