Characterization of the glutathione redox state in the Golgi apparatus [PDF]
Redox BiologyRedox homeostasis is crucial for cell function, and, in eukaryotic cells, studying it in a compartmentalized way is essential due to the redox variations between different organelles.
Carla Miró-Vinyals +5 more
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The Golgi apparatus: 100 years of progress and controversy. [PDF]
, 1998 Research on the Golgi apparatus has resulted in major advances in understanding its structure and functions, but many important questions remain unanswered.
Farquhar, MG, Palade, GE
core +3 more sources
Bridging the gap between glycosylation and vesicle traffic [PDF]
Frontiers in Cell and Developmental Biology, 2016 Glycosylation is recognised as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus.
Daniel eUngar, Peter eFisher
doaj +4 more sources
Ubiquitin-mediated degradation at the Golgi apparatus [PDF]
Frontiers in Molecular Biosciences, 2023 The Golgi apparatus is an essential organelle of the secretory pathway in eukaryotic cells. It processes secretory and transmembrane proteins and orchestrates their transport to other endomembrane compartments or the plasma membrane.
Lana Buzuk, Doris Hellerschmied
doaj +2 more sources
The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes [PDF]
Scientific ReportsWhite adipocytes are a major component of white adipose tissue (WAT) and help to maintain systemic metabolic homeostasis by storing energy and secreting adipokines. In mice deficient in the protein WWP1 (WW domain-containing E3 ubiquitin protein ligase 1)
Yuka Nozaki +8 more
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MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio [PDF]
eLifeThe reorientation of the Golgi apparatus is crucial for cell migration and is regulated by multipolarity signals. A number of non-centrosomal microtubules anchor at the surface of the Golgi apparatus and play a vital role in the Golgi reorientation, but ...
Peipei Xu +10 more
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A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer [PDF]
Discover OncologyBackground Gastric cancer (GC) remains a significant health burden, calling for the discovery of novel biomarkers. Golgi apparatus, a crucial cellular organelle involved in tumorigenesis, remains underexplored in GC research.
Ruyue Chen +3 more
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The Golgi Apparatus: A Voyage through Time, Structure, Function and Implication in Neurodegenerative Disorders. [PDF]
Cells, 2023 Mohan AG +5 more
europepmc +3 more sources
Biogenesis of specialized lysosomes in differentiated keratinocytes relies on close apposition with the Golgi apparatus [PDF]
Cell Death and DiseaseIntracellular organelles support cellular physiology in diverse conditions. In the skin, epidermal keratinocytes undergo differentiation with gradual changes in cellular physiology, accompanying remodeling of lysosomes and the Golgi apparatus.
Sarmistha Mahanty +8 more
doaj +2 more sources
European Journal of Histochemistry, 2009 The aim of the present investigation was to elucidate whether the Golgi apparatus undergoes photodamage following administration of the fluorogenic substrates Rose Bengal acetate (RBAc) and irradiation at the appropriate wavelength. Human HeLa cells were
C Soldani +5 more
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