Results 1 to 10 of about 75,593 (176)

Ubiquitin-mediated degradation at the Golgi apparatus [PDF]

Frontiers in Molecular Biosciences, 2023
The Golgi apparatus is an essential organelle of the secretory pathway in eukaryotic cells. It processes secretory and transmembrane proteins and orchestrates their transport to other endomembrane compartments or the plasma membrane.
Lana Buzuk, Doris Hellerschmied
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The Preparation of Golgi Apparatus-Targeted Polymer Dots Encapsulated with Carbon Nanodots of Bright Near-Infrared Fluorescence for Long-Term Bioimaging [PDF]

Molecules, 2023
As a vital organelle in eukaryotic cells, the Golgi apparatus is responsible for processing and transporting proteins in cells. Precisely monitoring the status of the Golgi apparatus with targeted fluorescence imaging technology is of enormous importance
Yiping Lu, Wei Song, Zhiquan Tang, Wenru Shi, Shumei Gao, Jun Wu, Yuan Wang, Hu Pan, Yangang Wang, Hong Huang   +9 more
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The effects of WWP1 overexpression on the golgi apparatus stress response and proteoglycan production in adipocytes [PDF]

Scientific Reports
White adipocytes are a major component of white adipose tissue (WAT) and help to maintain systemic metabolic homeostasis by storing energy and secreting adipokines. In mice deficient in the protein WWP1 (WW domain-containing E3 ubiquitin protein ligase 1)
Yuka Nozaki, Fumika Suwa, Kazuhiro Furuya, Masahiro Komeno, Shunsuke Hoshino, Yuhei Mizunoe, Kyohei Higashi, Masaki Kobayashi, Yoshikazu Higami   +8 more
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Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver

Journal of Lipid Research, 1969
It has been proposed that particles within tubules and vesicles of the Golgi apparatus of liver cells are precursors of very low density lipoproteins in blood plasma. To characterize these particles we isolated a cell fraction rich in Golgi apparatus and
Robert W. Mahley, Robert L. Hamilton, Virgil S. LeQuire   +2 more
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Characterization of the glutathione redox state in the Golgi apparatus [PDF]

Redox Biology
Redox homeostasis is crucial for cell function, and, in eukaryotic cells, studying it in a compartmentalized way is essential due to the redox variations between different organelles.
Carla Miró-Vinyals, Sarah Emmert, Gina Grammbitter, Alex Jud, Tobias Kockmann, Pablo Rivera-Fuentes   +5 more
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The organization and function of the Golgi apparatus in dendrite development and neurological disorders [PDF]

Genes and Diseases, 2023
Dendrites are specialized neuronal compartments that sense, integrate and transfer information in the neural network. Their development is tightly controlled and abnormal dendrite morphogenesis is strongly linked to neurological disorders.
Meilan Chen, Lu Xu, Yi Wu, Peter Soba, Chun Hu   +4 more
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MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio [PDF]

eLife
The reorientation of the Golgi apparatus is crucial for cell migration and is regulated by multipolarity signals. A number of non-centrosomal microtubules anchor at the surface of the Golgi apparatus and play a vital role in the Golgi reorientation, but ...
Peipei Xu, Rui Zhang, Zhengrong Zhou, Honglin Xu, Yuejia Li, Mengge Yang, Ruifan Lin, Yingchun Wang, Xiahe Huang, Qi Xie, Wenxiang Meng   +10 more
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Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner [PDF]

Cell Communication and Signaling, 2023
Background Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species H2O2 is one of the virulence factors of Streptococcus pneumoniae. The Golgi apparatus is essential for the inflammatory response
Björn Klabunde, André Wesener, Wilhelm Bertrams, Stephan Ringshandl, Luke D. Halder, Evelyn Vollmeister, Bernd Schmeck, Birke J. Benedikter   +7 more
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Golgi Apparatus Target Proteins in Gastroenterological Cancers: A Comprehensive Review of GOLPH3 and GOLGA Proteins [PDF]

Cells, 2023
The Golgi apparatus plays a central role in protein sorting, modification and trafficking within cells; its dysregulation has been implicated in various cancers including those affecting the GI tract.
Sandica Bucurica, Laura Gaman, Mariana Jinga, Andrei Adrian Popa, Florentina Ionita-Radu   +4 more
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A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer [PDF]

Discover Oncology
Background Gastric cancer (GC) remains a significant health burden, calling for the discovery of novel biomarkers. Golgi apparatus, a crucial cellular organelle involved in tumorigenesis, remains underexplored in GC research.
Ruyue Chen, Zengwu Yao, Lixin Jiang, Jinchen Hu   +3 more
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