Farquhar MG, Palade GE: The Golgi apparatus: 100 years of progress and controversy.Trends Cell Biol 1998, 8:2-10.Nelson WJ: W(h)ither the Golgi during mitosis?J Cell Biol 2000, 149:243-248.Palade GE: Intracellular aspects of the process of protein secretion.Science 1975, 189:347-388.Rothman JE, Wieland FT: Protein sorting by transport vesicles.Science ...
Ben Short, Francis A. Barr
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A distinct Golgi-targeting mechanism of dGM130 in Drosophila neurons
GM130 is a matrix protein that is conserved in metazoans and involved in the architecture of the Golgi apparatus. In neurons, Golgi apparatus and dendritic Golgi outposts (GOs) have different compartmental organizations, and GM130 localization is present
Guo Cheng+5 more
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A SNARE geranylgeranyltransferase essential for the organization of the Golgi apparatus
Protein prenylation is essential for many cellular processes including signal transduction, cytoskeletal reorganization, and membrane trafficking. Here, we identify a novel type of protein prenyltransferase, which we named geranylgeranyltransferase type ...
R. Shirakawa+13 more
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The asymmetrical structure of Golgi apparatus membranes revealed by in situ atomic force microscope. [PDF]
The Golgi apparatus has attracted intense attentions due to its fascinating morphology and vital role as the pivot of cellular secretory pathway since its discovery.
Haijiao Xu+5 more
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C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles. [PDF]
The Golgi apparatus is an intracellular compartment necessary for post-translational modification, sorting and transport of proteins. It plays a key role in mitotic entry through the Golgi mitotic checkpoint. In order to identify new proteins involved in
Vincent Fraisier+12 more
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An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning. [PDF]
The elaboration of dendrites in neurons requires secretory trafficking through the Golgi apparatus, but the mechanisms that govern Golgi function in neuronal morphogenesis in the brain have remained largely unexplored.
Nadia Litterman+7 more
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Decoupling polarization of the Golgi apparatus and GM1 in the plasma membrane.
Cell polarization is a process of coordinated cellular rearrangements that prepare the cell for migration. GM1 is synthesized in the Golgi apparatus and localized in membrane microdomains that appear at the leading edge of polarized cells, but the ...
Blaine Bisel+3 more
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Cytoplasmic dynein and its regulatory proteins in Golgi pathology in nervous system disorders
The Golgi apparatus is a dynamic organelle involved in processing and sorting of lipids and proteins. In neurons, the Golgi apparatus is important for the development of axons and dendrites and maintenance of their highly polarized morphology.
Dick eJaarsma, Casper eHoogenraad
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Retro-2 alters Golgi structure
Retro-2 directly interacts with an ER exit site protein, Sec16A, inhibiting ER exit of a Golgi tSNARE, Syntaxin5, which results in rapid re-distribution of Syntaxin5 to the ER. Recently, it was shown that SARS-CoV-2 infection disrupts the Golgi apparatus
Xihua Yue+7 more
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Positioning the Golgi Apparatus [PDF]
Ríos et al. (2004) report in this issue that the Golgi protein GMAP-210 is sufficient to confer pericentrosomal positioning and recruits gamma-tubulin and associated microtubule-nucleating ring complex proteins to Golgi membranes. The results raise the possibility that short microtubules emanate from the Golgi to mediate its organization and ...
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