Results 31 to 40 of about 956,222 (367)
Positioning the Golgi Apparatus [PDF]
Cell, 2004 Ríos et al. (2004) report in this issue that the Golgi protein GMAP-210 is sufficient to confer pericentrosomal positioning and recruits gamma-tubulin and associated microtubule-nucleating ring complex proteins to Golgi membranes. The results raise the possibility that short microtubules emanate from the Golgi to mediate its organization and ...
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Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling
FEBS Letters, 2019 In addition to the classical functions of the Golgi in membrane transport and glycosylation, the Golgi apparatus of mammalian cells is now recognised to contribute to the regulation of a range of cellular processes, including mitosis, DNA repair, stress ...
Prajakta Kulkarni-Gosavi +2 more
semanticscholar +1 more source
Predicting Sub-Golgi Apparatus Resident Protein With Primary Sequence Hybrid Features
IEEE Access, 2020 The Golgi apparatus is a significant membrane-bound organelle of eukaryotic cells that is made up of a series of flattened, stacked pouches (called cisternae).
Chunyu Wang +3 more
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The spinal muscular atrophy disease protein SMN is linked to the Golgi network. [PDF]
PLoS ONE, 2012 Proximal spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by deficiency of the ubiquitous Survival of Motor Neuron (SMN) protein. SMN has been shown to be transported in granules along the axon and moved through cytoskeletal elements.
Chen-Hung Ting +5 more
doaj +1 more source
Visualization of secretory cargo transport within the Golgi apparatus
Journal of Cell Biology, 2019 To describe trafficking of secretory cargo within the Golgi apparatus, the cisternal maturation model predicts that Golgi cisternae change their properties from cis to trans while cargo remains in the cisternae.
Kazuo Kurokawa +7 more
semanticscholar +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1998 The plant Golgi apparatus has an important role in protein glycosylation and sorting, but is also a major biosynthetic organelle that synthesises large quantities of cell wall polysaccharides. This is reflected in the organisation of the Golgi apparatus as numerous individual stacks of cisternae that are dispersed through the cell.
Paul Dupree, D. Janine Sherrier
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The Golgi Apparatus: Morphology and Function with Recent Facts
Bezmiâlem Science, 2019 At the center of the secretory pathway, the Golgi complex ensures correct processing and sorting of cargos towards their final destination sites which are the cytoplasm, plasma membrane, and endosome-lysosome system.
Mukaddes Eşrefoğlu
doaj +1 more source
GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues. [PDF]
PLoS ONE, 2012 The Golgi apparatus is the main site of glycan biosynthesis in eukaryotes. Better understanding of the membrane topology of the proteins and enzymes involved can impart new mechanistic insights into these processes.
Casper Søgaard +6 more
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Glycan processing in the Golgi -- optimal information coding and constraints on cisternal number and enzyme specificity [PDF]
eLife 2022, 2020 Many proteins that undergo sequential enzymatic modification in the Golgi cisternae are displayed at the plasma membrane as cell identity markers. The modified proteins, called glycans, represent a molecular code. The fidelity of this glycan code is measured by how accurately the glycan synthesis machinery realises the desired target glycan ...
arxiv +1 more source
Chemical Science, 2017 The targeting and long-term imaging of the Golgi apparatus have been realized via l-cysteine functionalized nanoprobes.
R. Li +9 more
semanticscholar +1 more source