Results 41 to 50 of about 75,593 (176)

Evidence for a Golgi-to-endosome protein sorting pathway in Plasmodium falciparum.

open access: yesPLoS ONE, 2014
During the asexual intraerythrocytic stage, the malaria parasite Plasmodium falciparum must traffic newly-synthesized proteins to a broad array of destinations within and beyond the parasite's plasma membrane.
Priscilla Krai   +2 more
doaj   +1 more source

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

open access: yesMolecular Systems Biology, 2012
The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia   +5 more
doaj   +1 more source

Fluid-membrane tethers: minimal surfaces and elastic boundary layers [PDF]

open access: yes, 2002
Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation of a tether in terms of the classical soap-film problem, which is applied to the case of a membrane disk under ...
arxiv   +1 more source

The neuronal Golgi in neural circuit formation and reorganization

open access: yesFrontiers in Neural Circuits
The Golgi apparatus is a central hub in the intracellular secretory pathway. By positioning in the specific intracellular region and transporting materials to spatially restricted compartments, the Golgi apparatus contributes to the cell polarity ...
Naoki Nakagawa, Naoki Nakagawa
doaj   +1 more source

An Age-dependent Feedback Control Model for Calcium and Reactive Oxygen Species in Yeast Cells [PDF]

open access: yesarXiv, 2022
Calcium and reactive oxygen species (ROS) interact with each other and play an important role in cell signaling networks. Based on the existing mathematical models, we develop an age-dependent feedback control model to simulate the interaction. The model consists of three subsystems: cytosolic calcium dynamics, ROS generation from the respiratory chain
arxiv  

ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation

open access: yesScientific Reports, 2023
Amyotrophic lateral sclerosis (ALS) is a severely debilitating neurodegenerative condition that is part of the same disease spectrum as frontotemporal dementia (FTD).
Audrey M. G. Ragagnin   +22 more
doaj   +1 more source

Golgi defect as a major contributor to lysosomal dysfunction

open access: yesFrontiers in Cell and Developmental Biology
The Golgi apparatus plays a crucial role in lysosome biogenesis and the delivery of lysosomal enzymes, essential for maintaining cellular homeostasis and ensuring cell survival. Deficiencies in Golgi structure and function can profoundly impact lysosomal
Sarah R. Akaaboune, Yanzhuang Wang
doaj   +1 more source

Preferred states of the apparatus [PDF]

open access: yesPramana-Journal of Physics, Vol 78(2) , 2012 , pp 175-186, 2012
A simple one dimensional model for the system-apparatus interaction is analyzed. The system is a spin-1/2 particle, and its position and momentum degrees constitutes the apparatus. An analysis involving only unitary Schrodinger dynamics illustrates the nature of the correlations established in the system-apparatus entangled state. It is shown that even
arxiv   +1 more source

Quantum Information in a Distributed Apparatus [PDF]

open access: yesFound.Phys.28:1005-1012,1998, 1998
We investigate the information provided about a specified distributed apparatus of n units in the measurement of a quantum state. It is shown that, in contrast to such measurement of a classical state, which is bounded by log (n+1) bits, the information in a quantum measurement is bounded by 3.7 x n^(1/2) bits.
arxiv   +1 more source

Disruption of the Golgi Apparatus and Contribution of the Endoplasmic Reticulum to the SARS-CoV-2 Replication Complex

open access: yesViruses, 2021
A variety of immunolabeling procedures for both light and electron microscopy were used to examine the cellular origins of the host membranes supporting the SARS-CoV-2 replication complex. The endoplasmic reticulum has long been implicated as a source of
Ted Hackstadt   +8 more
doaj   +1 more source

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