Results 41 to 50 of about 956,222 (367)
Membrane Trafficking in the Yeast Saccharomyces cerevisiae Model [PDF]
International Journal of Molecular Sciences, MDPI, 2015, 16 (1),
pp.1509 - 1525, 2018 The yeast Saccharomyces cerevisiae is one of the best characterized eukaryotic models. The secretory pathway was the first trafficking pathway clearly understood mainly thanks to the work done in the laboratory of Randy Schekman in the 1980s. They have isolated yeast sec mutants unable to secrete an extracellular enzyme and these SEC genes were ...
arxiv +1 more source
Chaos may enhance expressivity in cerebellar granular layer [PDF]
Neural Networks, Volume 136, April 2021, Pages 72-86, 2020 Recent evidence suggests that Golgi cells in the cerebellar granular layer are densely connected to each other with massive gap junctions. Here, we propose that the massive gap junctions between the Golgi cells contribute to the representational complexity of the granular layer of the cerebellum by inducing chaotic dynamics.
arxiv +1 more source
Golgi Dynamics: The Morphology of the Mammalian Golgi Apparatus in Health and Disease
Front. Cell Dev. Biol., 2019 In vertebrate cells the Golgi consists of individual stacks fused together into a compact ribbon structure. The function of the ribbon structure of the Golgi has only begun to be appreciated (De Matteis et al., 2008; Gosavi and Gleeson, 2017; Wei and ...
Christian Makhoul +2 more
semanticscholar +1 more source
The Stack of the Golgi Apparatus.
Archives of Histology and Cytology, 2002 One hundred years have passed since the discovery of "the internal reticular apparatus" by Camillo GOLGI. Investigations into the structure and function of the "Golgi apparatus" have raised more and more challenging issues for cell biologists. After long debate, many new findings have accumulated in the last 10 years as a result of the availability of ...
Shohei Yamashina, Hideaki Tamaki
openaire +4 more sources
eLife, 2016 The membrane-bound transcription factor ATF6α is activated by proteolysis during endoplasmic reticulum (ER) stress. ATF6α target genes encode foldases, chaperones, and lipid biosynthesis enzymes that increase protein-folding capacity in response to ...
Ciara M. Gallagher, P. Walter
semanticscholar +1 more source
The riddle of the plant vacuolar sorting receptors [PDF]
Protoplasma 226 (12/2005) 103-8, 2006 Proteins synthesized on membrane-bound ribosomes are sorted at the Golgi apparatus level for delivery to various cellular destinations: the plasma membrane or the extracellular space, and the lytic vacuole or lysosome. Sorting involves the assembly of vesicles, which preferentially package soluble proteins with a common destination.
arxiv +1 more source
Nature Communications, 2016 The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins.
Seongju Lee, Jaerak Chang, C. Blackstone
semanticscholar +1 more source
Branched Actin Maintains Acetylated Microtubule Network in the Early Secretory Pathway
Cells, 2021 In the early secretory pathway, the delivery of anterograde cargoes from the endoplasmic reticulum (ER) exit sites (ERES) to the Golgi apparatus is a multi-step transport process occurring via the ER-Golgi intermediate compartment (IC, also called ERGIC).
Azumi Yoshimura +3 more
doaj +1 more source
A multi-species model with interconversion, chipping and injection [PDF]
Phys. Rev. E 84, 031106 (2011), 2011 Motivated by the phenomenology of transport through the Golgi apparatus of cells, we study a multi-species model with boundary injection of one species of particle, interconversion between the different species of particle, and driven diffusive movement of particles through the system by chipping of a single particle from a site.
arxiv +1 more source
Targeting of proteins to the Golgi apparatus [PDF]
Glycoconjugate Journal, 1994 The Golgi apparatus maintains a highly organized structure in spite of the intense membrane traffic which flows into and out of this organelle. Resident Golgi proteins must have localization signals to ensure that they are targeted to the correct Golgi compartment and not swept further along the secretory pathway.
Rohan D. Teasdale +3 more
openaire +4 more sources