Re-defining the Golgi complex in Plasmodium falciparum using the novel Golgi marker PfGRASP [PDF]
Plasmodium falciparum, the causative agent of malaria, relies on a sophisticated protein secretion system for host cell invasion and transformation.
Cowman, Alan F. +6 more
core +1 more source
Predicting Sub-Golgi Apparatus Resident Protein With Primary Sequence Hybrid Features
The Golgi apparatus is a significant membrane-bound organelle of eukaryotic cells that is made up of a series of flattened, stacked pouches (called cisternae).
Chunyu Wang +3 more
doaj +1 more source
The spinal muscular atrophy disease protein SMN is linked to the Golgi network. [PDF]
Proximal spinal muscular atrophy (SMA) is a neurodegenerative disorder caused by deficiency of the ubiquitous Survival of Motor Neuron (SMN) protein. SMN has been shown to be transported in granules along the axon and moved through cytoskeletal elements.
Chen-Hung Ting +5 more
doaj +1 more source
Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver
It has been proposed that particles within tubules and vesicles of the Golgi apparatus of liver cells are precursors of very low density lipoproteins in blood plasma. To characterize these particles we isolated a cell fraction rich in Golgi apparatus and
Robert W. Mahley +2 more
doaj +1 more source
Form and function of the Golgi apparatus: scaffolds, cytoskeleton and signalling
In addition to the classical functions of the Golgi in membrane transport and glycosylation, the Golgi apparatus of mammalian cells is now recognised to contribute to the regulation of a range of cellular processes, including mitosis, DNA repair, stress ...
Prajakta Kulkarni-Gosavi +2 more
semanticscholar +1 more source
GO-PROMTO illuminates protein membrane topologies of glycan biosynthetic enzymes in the Golgi apparatus of living tissues. [PDF]
The Golgi apparatus is the main site of glycan biosynthesis in eukaryotes. Better understanding of the membrane topology of the proteins and enzymes involved can impart new mechanistic insights into these processes.
Casper Søgaard +6 more
doaj +1 more source
Visualization of secretory cargo transport within the Golgi apparatus
To describe trafficking of secretory cargo within the Golgi apparatus, the cisternal maturation model predicts that Golgi cisternae change their properties from cis to trans while cargo remains in the cisternae.
Kazuo Kurokawa +7 more
semanticscholar +1 more source
Protein trafficking through the endosomal system prepares intracellular parasites for a home invasion [PDF]
Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the apical secretory micronemes and rhoptries of apicomplexan parasites
A Fomovska +54 more
core +2 more sources
The Golgi Apparatus: Morphology and Function with Recent Facts
At the center of the secretory pathway, the Golgi complex ensures correct processing and sorting of cargos towards their final destination sites which are the cytoplasm, plasma membrane, and endosome-lysosome system.
Mukaddes Eşrefoğlu
doaj +1 more source
The targeting and long-term imaging of the Golgi apparatus have been realized via l-cysteine functionalized nanoprobes.
R. Li +9 more
semanticscholar +1 more source

