Results 141 to 150 of about 115,721 (241)

Pituitary Surgery - A Modern Approach /

, 2006
The management of pituitary adenomas and other sellar tumors is one of the most difficult tasks for neurosurgeons and endocrinologists. Optimal treatment requires a multidisciplinary approach; neurological, ophthalmological, and endocrinological tests ...
Laws Jr., E.R.
core  

Absence of Interaction Between 5α‐Reductase Inhibitors and Glucocorticoids on Incidence of Myocardial Infarction in People With Type 2 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9543-9551, October 2026.
ABSTRACT Aims People with Type 2 diabetes experience higher cardiometabolic risk, and both synthetic glucocorticoids and use of 5α‐reductase inhibitors have been individually linked to increased risk of myocardial infarction. We tested whether the increase in risk is exacerbated by co‐prescription of both drugs.
Haolan Tu, Chengsheng Ju, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Scottish Diabetes Research Network Epidemiology Group, Peter Hanlon, Robert Lindsay, David McAllister, John Petrie, Naveed Sattar, Brian Kennon, Sam Philip, Scott Cunningham, Huan Wang, William Berthon, Helen Colhoun, Paul McKeigue, Sarah Wild, Ewan R. Pearson, Li Wei, Ruth Andrew   +20 more
wiley   +1 more source

Ethanolamine plasmalogens increase luteinising hormone pulsatility and are associated with GPR61 expression in bovine gonadotrophin‐releasing hormone neurons

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Ethanolamine plasmalogens increased LH pulse frequency. GPR61 was expressed in GnRH neurons and gonadotrophs, suggesting a role in neuroendocrine regulation. Ethanolamine plasmalogens (EPls), but not choline plasmalogens (CPls), may act via GPR61 expressed in GnRH neurons in the preoptic area and in anterior pituitary gonadotrophs.
Hiroya Kadokawa, Tomoaki Kubo, Kana Kobayashi, Denis Karani Wanjiru, Yvan Bienvenu Niyonzima   +4 more
wiley   +1 more source

Genetic landscape of a neonatal hypogonadotropic hypogonadism series: Novel variants and phenotypic spectrum

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract To describe clinical presentation and genetic findings in a cohort of infants with congenital hypogonadotropic hypogonadism (CHH) diagnosed before 2 years of age. From a large cohort of patients who underwent next‐generation sequencing (NGS) for CHH between 2019 and 2025, we identified all patients tested at ≤2 years of age.
Karine Aouchiche, Laure Van Wormhoudt, Kevin Perge, Joanne Dornberger, Cindy Colson, Marine Delagrange, Clara Leroy, Jennifer Ledmazel, Vanessa Menut, Jessica Benarrous Jaillet, Djamel Bendifallah, Mohamad Hage Chehade, Christelle Dib, Anne Barlier, Thierry Brue, Rachel Reynaud, Alexandru Saveanu   +16 more
wiley   +1 more source

Multi‐Mechanistic Effects of Xylopia aethiopica Fruits on Uterine Fibroids: Insights From In Vivo and In Silico Evidence

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Xylopia aethiopica fruit extract modulates progesterone and estradiol levels in monosodium glutamate‐induced uterine fibroid models. In silico analyses reveal strong binding of its phytochemicals to progesterone, estrogen, VEGFR2, and TGF‐β receptors, indicating multi‐target anti‐fibroid actions involving hormonal regulation, anti‐angiogenesis, and ...
Adedokun Oluwasegun, Ume Ogochukwu, Akinsola Olubiyi, Agada Emmanuel, Adebiyi Omowumi, Idogho Eseoghena, Adedokun Folake, Adekunle Temilade   +7 more
wiley   +1 more source

Melatonin Regulates Growth‐Arrest and DNA‐Damage Genes GADD153, GADD45g and GADD34 in Experimental Varicocele

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT This study aimed to reveal the relationship between experimental varicocele and melatonin levels. Forty adult Wistar albino rats were used in this study. Control (C), Melatonin (M), Varicocele (V), Varicocele+Melatonin (V + M) were planned. Varicocele was created on the first day of the experiment by opening the abdominal area, narrowing the ...
Esra Önal, Numan Baydilli, Derya Karabulut   +2 more
wiley   +1 more source

Rethinking gonadotropin releasing hormone agonist suppression test: why it should be a gonadotropin releasing hormone antagonist suppression test. [PDF]

J Endocr Soc
Munshi R, Coutu Nadeau LP, Dahan MH.
europepmc   +1 more source

GnRH Promotes Gonadotropin Synthesis and Secretion in the Bovine Anterior Pituitary by Inhibiting METTL1-Mediated m7G Modification of FOXO1 mRNA. [PDF]

FASEB J
Xiao Y, Wang BB, Guo HX, Zhang YX, Zhang H, Chen CZ, Jiang H, Zhang Z, Zheng Y, Yuan B.   +9 more
europepmc   +1 more source

Testicular toll with viral intrusion: Molecular insights into the impact of chronic HIV infection on male fertility

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
The molecular mechanisms contributing to impaired fertility in HIV+ males remain poorly defined. Using a human immunodeficiency virus (HIV) transgenic (Tg) rat model, we demonstrate key structural and functional sperm regulators including cation channel of sperm (CatSper)1–4 channels and mitochondrial biogenesis genes were markedly downregulated ...
Tousif Ahmed Hediyal, Elizabeth M. Stone, Omar Shukri, Victoria L. Schaal, Amin Foroughi‐Nezhad, Murali Devanaboyina, Josef S. Crenshaw, Amir Elrefaie, Sree Kolli, Camryn N. Davis, Dinesh Pradhan, Sowmya V. Yelamanchili, Gurudutt Pendyala   +12 more
wiley   +1 more source

Transient gonadotropin suppression by exogenous testosterone decreases INSL3 in early puberty in boys with constitutional delay of growth and puberty. [PDF]

J Endocr Soc
Raivio T, Tanner M, Vaaralahti K, Hero M, Miettinen PJ, Varimo T.   +5 more
europepmc   +1 more source