Results 151 to 160 of about 126,611 (274)

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Transient gonadotropin suppression by exogenous testosterone decreases INSL3 in early puberty in boys with constitutional delay of growth and puberty. [PDF]

J Endocr Soc
Raivio T, Tanner M, Vaaralahti K, Hero M, Miettinen PJ, Varimo T.   +5 more
europepmc   +1 more source

Novel Compound Heterozygous RECQL4 Pathogenic Variants and Associated Phenotypes in a Chinese Patient With Rothmund‐Thomson Syndrome: Case Report and Literature Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
A Chinese patient with Rothmund‐Thomson syndrome type 2 carried compound heterozygous RECQL4 variants, including a novel frameshift variant c.2053del (p.Asp685Thrfs*5). The patient also presented with gynecomastia and low testosterone, a previously unreported endocrine phenotype.
Yuanyuan Wang, Lulu Li, Chunjiao Zheng, Min Li, Qian Yu   +4 more
wiley   +1 more source

Multi-omics reveals the pituitary-mediated neuroendocrine mechanisms during the transition from the onset-of-birth to the laying period in Wanxi white geese. [PDF]

Poult Sci
Li XJ, Yuan X, Chen S, Hou MM, Ren M, Li SH.   +5 more
europepmc   +1 more source

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang, Junxian Zhao, Fangxia Zou, Wanglin Jiang, Jianzhao Zhang, Pengfei Yu, Liang Ye, Xiaolin Sun, Chunmei Li, Jingwei Tian   +9 more
wiley   +1 more source

LHCGR phamacodynamic effects during follicular maturation. [PDF]

Front Endocrinol (Lausanne)
Perri C, Casarini L, Lazzaretti C.
europepmc   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, Volume 14, Issue 7, Page 1971-1987, October 2026.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

The extragonadal biology of gonadotropin hormones: should we rename these? [PDF]

Endocr Connect
Kim SM, Korkmaz F, Kang S, Sen F, Sims SL, Gimenez-Roig J, Cheliadinova U, Vasilyeva D, Barak O, Hutchison S, Macdonald A, Latif R, Goosens K, Frolinger T, Pallapati A, Rojekar S, Ryu V, Lizneva D, Yuen T, Zaidi M.   +19 more
europepmc   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, Volume 14, Issue 7, Page 1906-1928, October 2026.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente, Erica L. T. van den Akker, Metin Cetiner, Karine Clément, Elizabeth Forsythe, Alastair Garfield, Peter Kühnen, Gabriel Ángel Martos‐Moreno, David Meeker, Hermann L. Müller, Hanneke M. van Santen, Julia von Schnurbein, Bérénice Segrestin, Tomohiro Tanaka, Manuel Tena‐Sempere, Martin Wabitsch, Stefanie Zorn, I. Sadaf Farooqi   +17 more
wiley   +1 more source