Results 41 to 50 of about 78,942 (265)

DUSP1 Mitigates MSU-Induced Immune Response in Gouty Arthritis Reinforcing Autophagy

Frontiers in Bioscience-Landmark
Background: Persistent hyperuricemia can lead to the generation and deposition of monosodium urate (MSU) crystals. This can trigger gouty arthritis (GA), which in turn induces inflammation.
Jing Nie, Hongbin Qiu
doaj   +1 more source

Treatment of Gout with TCM Using Turmeric and Corn Silk: A Concise Review Article and Pharmacology Network Analysis [PDF]

, 2022
Haoyu Zhang, Huizhong Jiang, Mengya Zhao, Yan Xu, Jiabin Liang, Yufeng Ye, Hanwei Chen   +6 more
openalex   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Artificial sweeteners differentially activate sweet and bitter gustatory neurons in Drosophila

Scientific Reports
Artificial sweeteners are highly sweet, non-nutritive compounds that have become increasingly popular over recent decades despite research suggesting that their consumption has unintended consequences. Specifically, there is evidence suggesting that some
Christian Arntsen, Jake Grenon, Isabelle Chauvel, Stéphane Fraichard, Stéphane Dupas, Jérôme Cortot, Kayla Audette, Pierre-Yves Musso, Molly Stanley   +8 more
doaj   +1 more source

CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue

Cell Reports, 2023
Summary: Adipose-derived stem cells (ASCs) drive healthy visceral adipose tissue (VAT) expansion via adipocyte hyperplasia. Obesity induces ASC senescence that causes VAT dysfunction and metabolic disorders.
Zixin Zhou, Huiying Zhang, Yan Tao, Haipeng Jie, Jingyuan Zhao, Jinhao Zang, Huijie Li, Yalin Wang, Tianci Wang, Hui Zhao, Yuan Li, Chun Guo, Faliang Zhu, Haiting Mao, Lining Zhang, Fengming Liu, Qun Wang   +16 more
doaj   +1 more source

Onset of depression and anxiety among patients with gout after diagnosis: a population-based incident cohort study [PDF]

, 2022
Alyssa Howren, Eric C. Sayre, Hyon K. Choi, J. Antonio Aviña‐Zubieta, Kam Shojania, Jamie Yea Eun Park, Mary A. De Vera   +6 more
openalex   +1 more source

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

Arthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Management of Gout in the United States: A Claims‐based Analysis

ACR Open Rheumatology, 2020
Objective Gout is the most common inflammatory arthritis in the United States. Although numerous guidelines exist for the management of gout, they are not routinely implemented. This study evaluated the real‐world practice patterns in gout patients using
N. Lawrence Edwards, Naomi Schlesinger, Sanders Clark, Theresa Arndt, Peter E. Lipsky   +4 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Exploration of molecular biomarkers in ankylosing spondylitis transcriptomics

Frontiers in Immunology
BackgroundInflammation of the spine and sacroiliac joints is a hallmark of the chronic, progressive inflammatory illness known as ankylosing spondylitis (AS). The insidious onset and non-specific early symptoms of AS often lead to delays in diagnosis and
Yuanpiao Ni, Yuanpiao Ni, Linrui Zhong, Linrui Zhong, Yanhui Li, Yanhui Li, Zeng Zhang, Zeng Zhang, Bin Ming, Bin Ming, Yufeng Qing, Yufeng Qing, Quanbo Zhang, Quanbo Zhang   +13 more
doaj   +1 more source