Results 51 to 60 of about 937 (121)

Time Trends and Predictors of Gout Remission Over 6 Years. [PDF]

open access: yesArthritis Care Res (Hoboken)
Tabi-Amponsah AD   +5 more
europepmc   +1 more source

Intra-articular sustained-release colchicine is efficacious in an inflammatory arthritis rat model. [PDF]

open access: yesRMD Open
Grassot J   +11 more
europepmc   +1 more source

Hyperuricemia as a Ninth Upstream Gate in the Selenoprotein Axis: Uric Acid-Mediated NRF2 Suppression, RAGE-NF-κB Hepcidin Amplification, and Ferroptosis-Driven Hyperuricemic Nephropathy as Three Convergent Mechanisms Connecting Gout to the Selenoprotein Axis Framework

open access: yes
This paper proposes that hyperuricemia represents a ninth upstream gate in the Selenoprotein Axis operating through three simultaneous and non-redundant mechanisms: (1) uric acid-mediated NRF2 suppression reducing GPx4 expression and enabling ferroptosis in renal proximal tubular cells; (2) RAGE-NF-kB activation by urate crystals elevating IL-6 and ...
openaire   +3 more sources

Improvements in Health-Related Quality of Life With Treat-to-Target Urate-Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial. [PDF]

open access: yesArthritis Care Res (Hoboken)
Barry A   +16 more
europepmc   +1 more source

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