Results 41 to 50 of about 62,613 (212)
The Journal of Physiology, Volume 603, Issue 15, Page 4409-4432, 1 August 2025.Abstract figure legend PANX1 and PANX3 show opposite expression patterns in patient‐derived normal skin and cutaneous squamous cell carcinoma (cSCC) tumours, with PANX1 increased and PANX3 mRNA decreased in cSCC tumours compared to skin. Within the tumour PANX1 localizes to all regions, including tumour nests which house cSCC cancer cells and tumour ...
Brooke L. O'Donnell +11 more
wiley +1 more source
Peperomia pellucida (L.) Kunth: Traditional medicinal and its bioactivity [PDF]
, 2022 Peperomia pellucida (L.) Kunth (Piperaceae) has been long used as food ingredient and traditional medicine. This study aims to explain botany, utilization and bioactivity of P. pellucida.
Silalahi, Marina
core +1 more source
Gout and Cardiovascular Disease: Mechanisms, Risk Estimations, and the Impact of Therapies
Gout, Urate, and Crystal Deposition Disease, 2023 Gout is intimately associated with cardiovascular disease—especially in cases of an atherosclerosis origin, but also with others such as heart failure, atrial fibrillation, or aortic valve stenosis.
M. Andrés
semanticscholar +1 more source
Maternal Nutritional Environment and the Development of the Melanocortin System
Comprehensive Physiology, Volume 15, Issue 3, June 2025.Maternal metabolic impairments are related to an increased risk of obesity in the offspring throughout life, and changes in the development of the melanocortin system may be one of the mechanisms that promote increased food intake in the long term, leading to a positive energy balance and increased fat deposition.
Marina Galleazzo Martins +1 more
wiley +1 more source
Do centenarians die healthier than younger elders? A comparative epidemiological study in Spain [PDF]
, 2020 This study aims to describe the clinical course, drug use, and health services use characteristics during the last year of life of elders who die being centenarians and to identify key aspects differentiating them from elders who die at an earlier age ...
Aza-Pascual-Salcedo, M. +7 more
core +1 more source
, 2022 Additional file 1: Supplementary Figure 1. PLS-DA and RF analysis of serum metabolomic profiling at time zero. PLS-DA and RF analysis at time zero resulted in a good discrimination and prediction of the samples per BMI (A), but not per number of flares (B), or hyperuricemia (HU) > 8 mg/dL (C), or presence of tophi (D). Supplementary Figure 2.
Guma, Monica +11 more
openaire +1 more source
Colocalization Analysis Reveals Shared Genetic Loci Contributing to Gout and Metabolite Levels
Gout, Urate, and Crystal Deposition DiseaseGenetic association studies in gout have identified genetic variants in or near genes involved in the biosynthesis and transport of urate and in immunological pathways.
R. Takei +3 more
semanticscholar +1 more source
Association Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout.
Journal of the American Medical Association (JAMA), 2022 Importance Gout is associated with cardiovascular diseases. The temporal association between gout flares and cardiovascular events has not been investigated.
E. Cipolletta +5 more
semanticscholar +1 more source
Journal of Diabetes Research, Volume 2025, Issue 1, 2025.Purpose The purpose of this study is to explore the association between serum growth differentiation factor 15 (GDF15) and metabolic syndrome (MS), as well as its components in patients with Type 2 diabetes mellitus (T2DM). Patients and Methods Data on 125 patients with T2DM admitted to the Department of Endocrinology of the Second People′s Hospital of
Yiran Zhao +8 more
wiley +1 more source
Rheumatic conditions in human immunodeficiency virus infection [PDF]
, 2017 Many rheumatic diseases have been observed in HIV-infected persons. We, therefore, conducted a comprehensive literature search in order to review the prevalence, presentation and pathogenesis of rheumatic manifestations in HIV-infected subjects ...
Daikeler, T., Tyndall, A., Walker, U. A.
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