Results 231 to 240 of about 61,419 (246)

Structure and function of a near fully-activated intermediate GPCR-Gαβγ complex. [PDF]

Nat Commun
Bi M, Wang X, Wang J, Xu J, Sun W, Adediwura VA, Miao Y, Cheng Y, Ye L.   +8 more
europepmc   +1 more source

Development and pharmacological characterization of novel multi‐ calcitonin gene‐related peptide and pituitary adenylate cyclase‐activating peptide receptor antagonists

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to provide proof‐of‐concept that multi‐receptor antagonist peptides can be generated by covalently linking independent antagonist peptides that block calcitonin gene‐related peptide (CGRP8‐37) or pituitary adenylate cyclase‐activating peptide (PACAP)/vasoactive intestinal peptide (VIP) (PACAP6‐38) activity ...
Zoe Tasma, Andrew Siow, Paul W. R. Harris, Margaret A. Brimble, Debbie L. Hay, Christopher S. Walker   +5 more
wiley   +1 more source

Role of GPCR Signaling in Anthracycline-Induced Cardiotoxicity. [PDF]

Cells
Biswal N, Harish R, Roshan M, Samudrala S, Jiao X, Pestell RG, Ashton AW.   +6 more
europepmc   +1 more source

The regenerative wound healing effects and molecular mechanism of Isaria cicadae Miquel rice fermentation extract. [PDF]

Appl Microbiol Biotechnol
Wang Q, Hao W, Guo C, Cao H, Wang B, Li X, Yu R, Xu L, Li J.   +8 more
europepmc   +1 more source

Dynamic regulation of <i>Rgs16</i> and its correlation with Neuregulin1 expression in acute and chronic nerve injury. [PDF]

Front Cell Dev Biol
García-Bejarano M, Aucello R, Zen F, El Soury M, Cordero F, de la Fuente JM, Perroteau I, Ronchi G, Gambarotta G.   +8 more
europepmc   +1 more source

Single‐cell genomics meets systems neuroscience: Insights from mapping the brain circuitry of stress

Journal of Neuroendocrinology, EarlyView.
Abstract Responses to external and internal dangers is essential for survival and homeostatic regulation. Hypothalamic corticotropin‐releasing hormone neurons (CRHNs) play a pivotal role in regulating neuroendocrine responses to fear and stress.
Naresh K. Hanchate
wiley   +1 more source

Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control

Journal of Neuroendocrinology, EarlyView.
Abstract Kisspeptin (KP) signaling in the brain is defined by the anatomical distribution of KP‐producing neurons, their fibers, receptors, and connectivity. Technological advances have prompted a re‐evaluation of these chemoanatomical aspects, originally studied in the early years after the discovery of KP and its receptor Kiss1r.
Limei Zhang, Vito Salvador Hernández, Mario Alberto Zetter, Oscar Rene Hernández‐Pérez, Rafael Hernández‐González, Ignacio Camacho‐Arroyo, Lee E. Eiden, Robert P. Millar   +7 more
wiley   +1 more source

Detection of Human GPCR Activity in Drosophila S2 Cells Using the Tango System. [PDF]

Int J Mol Sci
Salim E, Hori A, Matsubara K, Takano-Shimizu T, Pratomo AR, Marianne M, Syahputra A, Husori DI, Inoue A, Abdullah MA, Shamsudin NF, Rullah K, Kuraishi T.   +12 more
europepmc   +1 more source

Structural insights into KSHV-GPCR constitutive activation and CXCL1 chemokine recognition. [PDF]

Proc Natl Acad Sci U S A
Liu A, Liu Y, Llinàs Del Torrent Masachs C, Zhang W, Pardo L, Ye RD.   +5 more
europepmc   +1 more source

GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states. [PDF]

BMC Bioinformatics
Liu F, Zhou H, Li X, Zhou L, Yu C, Zhang H, Bu D, Liang X.   +7 more
europepmc   +1 more source