Results 161 to 170 of about 34,963 (198)

Glycolytic Enzymes Are Part of an Oncogenic Network in AML. [PDF]

Cells
Nagel S, Meyer C, Pommerenke C.
europepmc   +1 more source

Diverse ancestral myosin motors generate and segregate distinct types of nanocluster-rich domains at the plasma membrane

Sil P, van Zanten TS, Jahnavi S, Bansal A, Saha S, Mahajan B, Kumar M, Singh PP, Rao M, Mayor S.   +9 more
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Deletion of the GPI pre-anchor sequence in human p97—a general approach for generating the soluble form of GPI-linked proteins

Protein Expression and Purification, 2004
Melanotransferrin, also named p97, belongs to the transferrin-like group of iron-binding proteins. Unlike the other members of this family, p97 exists in two forms-one soluble form and one attached to the cell membrane by a glycosylphosphatidylinositol (GPI) anchor.
Wilfred Jefferies
exaly   +3 more sources

POLARIZED SORTING OF GPI-LINKED PROTEINS IN EPITHELIA AND MEMBRANE MICRODOMAINS

Cell Biology International Reports, 1991
Taken together, our results with endogenous and transfected GPI-anchored proteins (summarized in Table 6) suggest that covalent attachment to GPI functions as an apical transport signal in polarized epithelial cells. This is the first example of a well-defined targeting signal for the post-Golgi sorting of plasma membrane proteins in polarized ...
M P, Lisanti, E, Rodríguez-Boulan
openaire   +2 more sources

Cellular Expression of a GPI-Linked T Cell Activation Protein

Cellular Immunology, 1994
A T cell activation protein was identified by generating a monoclonal antibody (anti-D2) against a gamma delta T cell receptor bearing gibbon ape T cell line (MLA144). Immunoprecipitation studies revealed three polypeptides of 180, 150, and 120 kDa. The antigen was also found to be expressed on endothelial cells in vivo and in vitro and on tumor cell ...
A, Haregewoin, K, Solomon, R C, Hom, G, Soman, J M, Bergelson, A K, Bhan, R W, Finberg   +6 more
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Ectodomain interactions of leukocyte integrins and pro-inflammatory GPI-linked membrane proteins

Journal of Pharmaceutical and Biomedical Analysis, 1997
Although glycosylphosphatidyl-inositol (GPI) linked membrane proteins do not possess transmembrane or cytosolic sequences they elicit transmembrane signals. Using microscopic fluorescence imaging and resonance energy transfer (RET) techniques we have shown that certain pro-inflammatory GPI-linked membrane proteins can interact with leukocyte beta 2 ...
H R, Petty, A L, Kindzelskii, Y, Adachi, R F, Todd   +3 more
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Lipid Rafts, Caveolae and GPI-Linked Proteins

2012
Lipid rafts and caveolae are specialized membrane microdomains enriched in sphingolipids and cholesterol. They function in a variety of cellular processes including but not limited to endocytosis, transcytosis, signal transduction and receptor recycling.
Reeves, V.L., Thomas, C.M.G., Smart, E.J.   +2 more
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The presence of GPI-linked protein(s) in an archaeobacterium, Sulfolobus acidocaldarius, closely related to eukaryotes

Biochimica et Biophysica Acta (BBA) - General Subjects, 1997
GPI-anchored proteins are distributed ubiquitously in eukaryotes, but not in procaryotes. By metabolic-labeling of Sulfolobus acidocaldarius cells, 14C-radiolabeled precursors of GPI and caldarchaetidylinositol were incorporated into 120, 143 and 185 kDa proteins.
T, Kobayashi, R, Nishizaki, H, Ikezawa
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Phase partitioning detects differences between phospholipase-released forms of alkaline phosphatase — a GPI-linked protein

Biochimica et Biophysica Acta (BBA) - General Subjects, 1993
A number of enzymes are known to release alkaline phosphatase and other glycan phosphatidylinositol-anchored proteins from membrane surfaces. We describe a novel approach to detect and measure these activities by partitioning in aqueous phase systems. The procedures avoid the complications of micelle-formation involving hydrophobic molecules that may ...
F D, Raymond, D W, Moss, D, Fisher
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Investigating the role of murine epididymosomes and uterosomes in GPI‐linked protein transfer to sperm using SPAM1 as a model

Molecular Reproduction and Development, 2008
AbstractSperm uptake of glycosyl phosphatidylinositol (GPI)‐linked proteins from luminal fluids has been shown to occur in male and estrous female reproductive tracts. In males, this is attributed to membranous vesicles secreted into the epididymis and prostate. While epididymosomes have been characterized, there have been no reports of the presence of
Genevieve S, Griffiths, Deni S, Galileo, Kristen, Reese, Patricia A, Martin-Deleon   +3 more
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