Growth factor‐induced release of a glycosyl‐phosphatidylinositol (GPI)‐linked protein from the HEp‐2 human carcinoma cell line [PDF]
The release of a GPI‐linked oncofetal protein (PLAP) from HEp‐2 cells has been studied as an indicator of endogenous PI‐specific PLC activation. A non‐hydrolysable GTP analogue, EGF and insulin all produced a dose‐dependent release of PLAP from these cells.
Roberts, Julia M. +2 more
openaire +2 more sources
Genome-wide diversity and gene expression profiling of Babesia microti isolates identify polymorphic genes that mediate host-pathogen interactions [PDF]
Babesia microti, a tick-transmitted, intraerythrocytic protozoan parasite circulating mainly among small mammals, is the primary cause of human babesiosis.
Ben Mamoun, Choukri +31 more
core +3 more sources
PredGPI: a GPI-anchor predictor
Background Several eukaryotic proteins associated to the extracellular leaflet of the plasma membrane carry a Glycosylphosphatidylinositol (GPI) anchor, which is linked to the C-terminal residue after a proteolytic cleavage occurring at the so called ω ...
Casadio Rita +2 more
doaj +1 more source
Genome-wide prediction of the polymorphic Ser gene family in Tetrahymena thermophila based on motif analysis. [PDF]
Even though antigenic variation is employed among parasitic protozoa for host immune evasion, Tetrahymena thermophila, a free-living ciliate, can also change its surface protein antigens.
Patrath Ponsuwanna +2 more
doaj +1 more source
The trypanosomal transferrin receptor of trypanosoma brucei : a review [PDF]
Iron is an essential element for life. Its uptake and utility requires a careful balancing with its toxic capacity, with mammals evolving a safe and bio-viable means of its transport and storage. This transport and storage is also utilized as part of the
Kariuki, Christopher K. +2 more
core +2 more sources
Proteomic Analysis to Identify Tightly-Bound Cell Wall Protein in Rice Calli. [PDF]
Rice is a model plant widely used for basic and applied research programs. Plant cell wall proteins play key roles in a broad range of biological processes. However, presently, knowledge on the rice cell wall proteome is rudimentary in nature.
Chen, Xiong Yan +10 more
core +1 more source
Epididymosomes: transfer of fertility-modulating proteins to the sperm surface
A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation.
Patricia A Martin-DeLeon
doaj +1 more source
Lactoferrin efficiently counteracts the inflammation-induced changes of the iron homeostasis system in macrophages [PDF]
Human lactoferrin (hLf), an 80-kDa multifunctional iron-binding cationic glycoprotein, is constitutively secreted by exocrine glands and by neutrophils during inflammation. hLf is recognized as a key element in the host immune defense system.
Aisen +31 more
core +2 more sources
A transferrin-like GPI-linked iron-binding protein in detergent-insoluble noncaveolar microdomains at the apical surface of fetal intestinal epithelial cells. [PDF]
A GPI-anchored 80-kD protein was found to be the major component of detergent-insoluble complexes, prepared from fetal porcine small intestine, constituting about 25% of the total amount of protein. An antibody was raised to the 80-kD protein, and by immunogold electron microscopy of ultracryosections of mucosal tissue, the protein was localized to the
Danielsen, E M, van Deurs, B
openaire +2 more sources
Semaphorin 4C accelerates disease progression and enables disease detection in breast cancer
Semaphorins constitute a diverse family of widely expressed transmembrane, diffusible, and GPI-linked proteins with versatile physiologic functions in orchestrating nerve system development, immune homeostasis, angiogenesis, and cell metabolism ...
Li Huayi +5 more
doaj +1 more source

